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Senden-4 nanoemulsion and preparation method thereof
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A technology of nanoemulsion and senden, which is applied in the field of senden-4 nanoemulsion and its preparation, can solve the problems of unseen and unseen literature reports on external use of preparations, and achieve the effect of expanding the scope of use
Inactive Publication Date: 2021-11-16
内蒙古自治区国际蒙医医院
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The medicine is composed of 4 flavors, according to the order of the emperor, minister and assistant envoy, it is 15g of xanthus, 9g of toosendan, 3g of gardenia, and 3g of myrobalan. It has the function of clearing away heat and drying yellow water, and is used to treat gout, arthritis, edema, etc. Symptoms, the existing Chinese literature reports include traditional decoctions and capsules, but no other preparations have been reported, nor have there been any literature reports on the topical use of this preparation
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Embodiment 1
[0022] A kind of Sendon-4 nanoemulsion is prepared by the following method:
[0024] S2. Mix Tween-80 and ethyl acetate and stir evenly. After the water temperature is kept at 40-60 degrees, stop stirring, add anhydrous ethanol, continue stirring for 30 minutes, stop stirring, and add dropwise with a plastic tip dropper and heat it to 40 degrees in advance. -60 degrees of Sendeng-4 extract, after 3-8 hours of dropwise addition, keep it at 40-60 degrees for 1 hour, turn off the heating, reduce to room temperature, add other auxiliary materials, and stir evenly, that is, it is obtained.
Embodiment 2
[0026] A kind of Sendon-4 nanoemulsion is prepared by the following method:
[0028] S2. Mix Tween-80 and ethyl acetate and stir evenly. After the water temperature is kept at 40-60 degrees, stop stirring, add anhydrous ethanol, continue stirring for 30 minutes, stop stirring, and add dropwise with a plastic tip dropper and heat it to 40 degrees in advance. -60 degrees of Sendeng-4 extract, after 3-8 hours of dropwise addition, keep it at 40-60 degrees for 1 hour, turn off the heating, reduce to room temperature, add other auxiliary materials, and stir evenly, that is, it is obtained.
[0029] The nanoemulsion obtained in Example 1 and Example 2 was centrifuged at 12,000 r·min-1 for 20 min, and the nanoemulsion was still clear and uniform in appearance, ...
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Abstract
The invention discloses a Senden-4 nanoemulsion and a preparation method thereof. The nanoemulsion is prepared from ethyl acetate, anhydrous ethanol, Tween-80, an extract of Senden-4, a preservative, ascorbic acid and azone. to make. The invention innovatively prepares the traditional oral Mongolian medicine into a dermatological external preparation through new preparation work, which is used for treating skin diseases and being used as a skin care product, thereby expanding the application scope of the medicine.
Description
technical field [0001] The invention relates to the field of Mongolian medicine, in particular to a Senden-4 nanoemulsion and a preparation method thereof. Background technique [0002] The Mongolian medicine compound Sendeng-4 decoction is a commonly used anti-rheumatic medicine in Mongolian medicine, which is included in the "Inner Mongolian Mongolian Patent Medicine Standards". The medicine is composed of 4 flavors, according to the order of monarchs, ministers and assistants, they are Wenguanmu 15g, Sichuan neem 9g, gardenia 3g, myrobalan 3g. It has the functions of clearing heat and drying yellow water. It is used to treat gout, arthritis, edema, etc. Disease, the existing Chinese literature reports in addition to traditional decoction, there are capsules, no other preparation reports, and no literature reports on the external use of the preparation. SUMMARY OF THE INVENTION [0003] In order to solve the above problems, the present invention provides a Sendon-4 nano...
Claims
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Application Information
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