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Medicine composition for diuresis and preparation method and application thereof

A composition and drug technology, applied in the field of diuretic pharmaceutical composition and its preparation and application, can solve the problems of insignificant curative effect, water and electrolyte disorder, long course of treatment, etc., achieve broad market application prospects, increase compliance, long-lasting effects

Inactive Publication Date: 2019-07-26
SICHUAN ACAD OF CHINESE MEDICINE SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In recent years, studies at home and abroad have found that long-term use of diuretics has a variety of toxic and side effects on the human body, such as thiazide diuretics. Especially digitalis drug poisoning caused by hypokalemia in heart failure, severe cases can cause arrhythmia, arteriosclerosis, coronary heart disease and diabetes, etc.
However, studies at home and abroad have shown that some traditional Chinese medicines and traditional Chinese medicine compound preparations have obvious diuretic effects and do not cause electrolyte disturbances, and are favored by patients because of their small side effects and long-lasting drug effects. Currently, there are many studies on diuretic Chinese medicine compositions , but there is a long course of treatment, or the problem of insignificant curative effect

Method used

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  • Medicine composition for diuresis and preparation method and application thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Embodiment 1, the preparation of pharmaceutical composition of the present invention

[0022] 1. Take 30g white lentils, 40g red beans, 40g poria cocos, 15g lotus leaves, 10g cassia seeds, 40g radish seeds, 30g hemp seeds, 30g gorgon seeds, 30g yams, 40g coix seed, 50g wax gourd kernels, 20g mulberries, 15g ginseng, fried Suanzaoren 10g, black sesame 100g, fungus 60g, red dates 80g.

[0023] 2. Take the raw materials in the prescribed amount, and weigh the raw materials according to the weight ratio; except black sesame, soak the fungus for 2-3 hours, steam with other medicines, and dry at 60°C. Black sesame is roasted, mixed with other raw materials, powdered, and passed through a 100-mesh sieve. After all are mixed evenly, the medicinal powder is taken to prepare a powder. Packed in 40g per bag, sterilized by irradiation, and become powder.

[0024] How to use: Take it twice a day, one bag each time.

Embodiment 2

[0025] Embodiment 2, the preparation of pharmaceutical composition of the present invention

[0026] 1. Take 15g white lentils, 20g red beans, 20g poria cocos, 7.5g lotus leaves, 5g cassia seeds, 20g radish seeds, 15g hemp seeds, 15g gorgon seeds, 15g yams, 20g coix seed, 25g wax gourd kernels, 10g mulberries, 7.5g ginseng , Fried Suanzaoren 5g, black sesame 50g, fungus 30g, red dates 40g.

[0027] 2. Take the raw materials in the prescribed amount, and weigh the raw materials according to the weight ratio; except black sesame, soak the fungus for 2-3 hours, steam with other medicines, and dry at 60°C. Black sesame is roasted, mixed with other raw materials, powdered, and passed through a 100-mesh sieve. After all are mixed evenly, the medicinal powder is taken to prepare a powder. Packed in 40g per bag, sterilized by irradiation, and become powder.

[0028] How to use: Take it twice a day, one bag each time.

Embodiment 3

[0029] Embodiment 3, the preparation of pharmaceutical composition of the present invention

[0030] 1. Take 3g of white lentils, 4g of red beans, 4g of poria cocos, 1.5g of lotus leaves, 1g of cassia seeds, 4g of radish seeds, 3g of hemp seeds, 3g of gorgon, 3g of yams, 4g of coix seed, 5g of wax gourd kernels, 2g of mulberries, and 1.5g of ginseng 1. Stir-fried jujube kernels 1g, black sesame 10g, fungus 6g, red dates 8g.

[0031] 2. Take the raw materials of the prescription amount, add 10 times the volume of water, soak for hair, boil for 20 minutes, filter; add 5 times the volume of water for the filter residue, boil for 15 minutes; combine the two filtrates, and concentrate to 200ml.

[0032] 3. How to use: take twice a day, 100ml each time.

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Abstract

The invention provides a medicine composition for diuresis. The medicine composition is prepared from, by weight, 3-40 parts of semen lablab album, 4-50 parts of semen phaseoli, 4-50 parts of poria cocos, 1.5-25 parts of folium nelumbinis, 1-20 parts of semen cassiae, 4-50 parts of semen raphani, 3-40 parts of semen cannabis, 3-40 parts of semen euryales, 3-40 parts of rhizoma dioscoreae, 4-50 parts of semen coicis, 5-60 parts of fructus benincasae, 2-30 parts of fructus mulberry, 1.5-25 parts of radix ginseng, 1-20 parts of semen ziziphi spinosea, 10-110 parts of semen sesami nigrum, 6-70 parts of auricularia polytricha and 8-90 parts of fructus ziziphi jugubae. The medicine composition tonifies qi and blood, clears damp to promote diuresis, has diuresis effect due to matching of medicinal and edible traditional Chinese medicine and is free of causing electrolyte disorder, little in side effect, short in treatment course, lasting in efficacy, high in safety and wide in market application prospect.

Description

technical field [0001] The invention relates to a diuretic pharmaceutical composition and its preparation method and application. Background technique [0002] Diuretics can excrete sodium and diuresis, reduce blood volume, decrease cardiac blood output, and lower blood pressure. Studies have found that traditional Chinese medicine can cause a negative balance of sodium and water in the body through sodium excretion and diuresis, reduce cell fluid and blood volume, and then lower blood pressure. Edema and ascites caused by other diseases, widely used clinically. [0003] In recent years, studies at home and abroad have found that long-term use of diuretics has a variety of toxic and side effects on the human body, such as thiazide diuretics. Especially digitalis drug poisoning caused by hypokalemia in heart failure, severe cases can cause arrhythmia, arteriosclerosis, coronary heart disease and diabetes. However, studies at home and abroad have shown that some traditional...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8994A61P7/10
CPCA61K36/07A61K36/076A61K36/185A61K36/258A61K36/31A61K36/42A61K36/48A61K36/482A61K36/60A61K36/605A61K36/62A61K36/725A61K36/8945A61K36/8994A61P7/10A61K2300/00
Inventor 罗霞苏琛江南王罡姚珂鄢小君
Owner SICHUAN ACAD OF CHINESE MEDICINE SCI
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