Rheumatism bone pain plaster capable of being directly applied to surface of trauma skin

A plaster and wound technology, applied in the field of traditional Chinese medicine, can solve the problems of poor air permeability, high recurrence rate, and poor targeting of plaster transdermal plaster, and achieve the effects of obviously treating rheumatism pain, improving the number of swollen joints, and good transdermal absorption rate.

Inactive Publication Date: 2019-08-30
广西壮族自治区花红药业集团股份公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The shortcoming of the plaster of rheumatic bone disease on the market is that some plasters are poorly targeted, and a plaster treats multiple diseases, and the drug effect is not ideal; the curative effect is slow, the sticking treatment time is long, the drug effect time is short, and the recurrence rate is high; and its allergies The rate is high, and many patients cannot use it continuously; at the same time, transdermal plasters have poor air permeability, and most rheumatic bone pain medicines are contraindicated when used on wounds, that is, they cannot be used on new breaks in the skin, so the scope of application is narrow

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] In this embodiment, a rheumatic bone pain plaster that can be directly applied on the surface of the wounded skin is proposed, including the following raw materials in parts by weight: 200 parts of sesame oil, 10 parts of raw Aconitum aconiti, 20 parts of amber, 10 parts of Anonymous, and 25 parts of calcined gypsum , 20 parts of frankincense, 20 parts of Angelica dahurica, 30 parts of Fangji, 10 parts of Fangfeng, 15 parts of Yuanhu, 20 parts of pearl, 15 parts of lovage, 10 parts of Shenjincao, 25 parts of myrrh, 15 parts of cinnamon, 8 parts of musk, saffron 15 parts, calamine 15 parts;

[0022] Its preparation method comprises the following steps:

[0023] 1) Select 200 parts of high-quality sesame oil, 10 parts of raw Aconitum aconiti, 20 parts of amber, 10 parts of Wumingyi, 25 parts of calcined gypsum, 20 parts of frankincense, 20 parts of Angelica dahurica, and 30 parts of Fangji which conform to the 2015 edition of "Chinese Pharmacopoeia" , 10 parts of Fangfen...

Embodiment 2

[0025] In this embodiment, a rheumatic bone pain plaster that can be directly applied on the surface of the wounded skin is proposed, including the following raw materials in parts by weight: 350 parts of sesame oil, 20 parts of raw Aconitum aconiti, 30 parts of amber, 20 parts of Anonymous, and 35 parts of calcined gypsum , 30 parts of frankincense, 25 parts of Angelica dahurica, 40 parts of Fangji, 15 parts of Fangfeng, 20 parts of Yuanhu, 30 parts of pearl, 25 parts of lovage, 30 parts of Shenjincao, 35 parts of myrrh, 20 parts of cinnamon, 13 parts of musk, saffron 25 parts, calamine 25 parts;

[0026] The preparation method comprises the following steps: 1) selecting 350 parts of high-quality sesame oil, 20 parts of Shengchuanwu, 30 parts of amber, 20 parts of Wumingyi, 35 parts of calcined gypsum, 30 parts of frankincense, 25 parts of Angelica dahurica, 40 parts of Fangji, 15 parts of Fangfeng, 20 parts of Yuanhu, 30 parts of Pearl, 25 parts of Duhuo, 30 parts of Shenjin...

Embodiment 3

[0028] Propose a kind of plaster for rheumatic bone pain that can be directly applied on the surface of wounded skin in this embodiment, including the following raw materials in parts by weight: 275 parts of sesame oil, 14 parts of Aconitum aconiti, 24 parts of amber, 12 parts of anonymous, and 28 parts of calcined gypsum , 23 parts of Frankincense, 22 parts of Angelica, 33 parts of Fangji, 12 parts of Fangfeng, 16 parts of Yuanhu, 22 parts of Pearl, 17 parts of Duhuo, 15 parts of Shenjincao, 28 parts of Myrrh, 16 parts of Cinnamon, 10 parts of Musk, Saffron 18 parts, calamine 18 parts;

[0029] Its preparation method comprises the following steps:

[0030] 1) Select 275 parts of high quality sesame oil, 14 parts of Aconitum aconitum, 24 parts of amber, 12 parts of Anonymous, 28 parts of calcined gypsum, 23 parts of frankincense, 22 parts of Angelica dahurica, and 33 parts of Fangji which conform to the 2015 edition of "Chinese Pharmacopoeia" , 12 parts of Fangfeng, 16 parts ...

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PUM

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Abstract

The invention discloses a rheumatism bone pain plaster capable of being directly applied to surface of trauma skin. A formula comprises sesame oil, unprocessed radix aconiti, amber, pyrolusite, calcined gypsum, frankincense, angelica roots, mealy fangji roots, divaricate saposhnikovia roots, rhizoma corydalis, pearl, radix angelicae pubescentis, common clubmoss herb, myrrh, cassia bark, musk, saffron and calamine. The rheumatism bone pain plaster overcomes the defect that traditional plaster can only be applied to affected parts instead of skin wounds, can be directly applied to newly piercedskin surfaces and has good transdermal absorptivity and good plaster viscosity. Meanwhile, the plaster can significantly improve DAS28, VAS pain scores, erythrocyte sedimentation rate, C-reactive protein and other indexes, the life quality of a patient is improved, and a new thought is provided for treatment of rheumatism bone pain by the plaster.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a rheumatic bone pain plaster which can be directly applied on the surface of wounded skin. Background technique [0002] Plasters have a long history of application in our country. Vegetable or animal oils are added to make a jelly-like substance, which can be pasted on the affected area for a long time on one side of cloth, paper or leather. The medicine in the plaster is directly applied to the acupuncture points on the body surface. , the property of the medicine permeates the subcutaneous tissue from the surface to the inside through the fur. On the one hand, the relative advantage of the drug concentration is produced locally. So as to exert the greatest systemic pharmacological effect. Traditional injection and oral therapy damage nerves, blood vessels, muscles and other tissues, making it difficult for patients to accept, and these methods are easy ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A61K9/70A61P29/00A61P19/08A61P19/02A61P17/02A61K35/618A61K35/55A61K35/10A61K33/32A61K33/30A61K33/06
CPCA61K36/88A61K36/714A61K36/66A61K36/59A61K36/54A61K36/328A61K36/324A61K36/238A61K36/232A61K36/11A61K35/618A61K35/55A61K35/10A61K33/32A61K33/30A61K33/06A61K9/7023A61P29/00A61P19/08A61P19/02A61P17/02A61K2236/35A61K2300/00
Inventor 韦飞燕张伟张艳华刘春明张鹏
Owner 广西壮族自治区花红药业集团股份公司
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