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Composition capable of orifice-freeing and restoring consciousness and preparation thereof

A technology of invigorating and refreshing the brain and composition, which is applied in the direction of drug combination, active ingredients of hydroxyl compounds, non-active ingredients of polymer compounds, etc., which can solve problems such as excessive stimulation, unclear drug effect persistence, loss of volatile oil, etc., and achieve easy portability , good effect of clearing the mind and refreshing the brain, and quick effect

Inactive Publication Date: 2019-11-01
HAINAN MEDICAL COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Patent CN 108704111A discloses a refreshing external composition, which contains volatile oil of traditional Chinese medicine, but no clinical trials have proved its refreshing effect, and the composition needs to be prepared at high temperature, which is easy to cause loss of volatile oil and long-lasting drug effect Sex is more ambiguous
Volatile plasters currently available in the market are pungent and irritating, and when applied to the skin, there are excessive irritation and even allergies. The refreshing effect after nasal inhalation is not good and cannot last
And the market also lacks the refreshing preparation that takes nasal passage as a means

Method used

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  • Composition capable of orifice-freeing and restoring consciousness and preparation thereof
  • Composition capable of orifice-freeing and restoring consciousness and preparation thereof
  • Composition capable of orifice-freeing and restoring consciousness and preparation thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0029] Embodiment 1 composition preparation of the present invention

[0030] Recipe: menthol 0.2g: borneol 0.2g: pepper oil 0.9ml: clove oil 0.3ml: peppermint oil 0.5ml: frankincense oil 1ml

[0031] Preparation method: Mix borneol and menthol, then add pepper oil, clove oil, peppermint oil, frankincense oil and mix well to obtain the formula oil.

Embodiment 2

[0032] Embodiment 2 Nasal inhalation agent of the present invention

[0033] Example 1 0.5g of recipe oil, 0.6g of kaolin, 0.3g of sodium alginate, 0.2g of gum arabic, 1.0g of β-cyclodextrin, 0.5g of recipe oil, 0.2g of tartaric acid, 2.5g of purified water, sodium polyacrylate 0.2g, aluminum glycylate 0.1g, EDTA 0.1g, glycerin 12g.

[0034] Preparation:

[0035] 1) Weigh the raw and auxiliary materials according to the proportioning ratio;

[0036] 2) Take the recipe oil, grind it with β-cyclodextrin, then add kaolin, sodium alginate, and gum arabic to grind it evenly into phase A; mix sodium polyacrylate, aluminum glycolate, EDTA, and glycerin into phase B; Take tartaric acid, add water and dissolve it into phase C;

[0037] 3) Mix A and B well, then add phase C and mix evenly, and stir until it becomes thick.

[0038] The beneficial effects of the present invention will be specifically described below through test examples.

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PUM

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Abstract

The invention provides a composition capable of orifice-freeing and restoring consciousness. The composition is prepared is prepared from the following raw materials in parts by weight: 0.1-0.3 part of menthol, 0.1-0.3 part of borneol, and 0.6-1.2 parts of pepper oil, 0.1-0.5 part of clove oil, 0.2-0.7 part of peppermint oil and 0.8-1.2 parts of mastic oil. According to the composition capable ofrelieving stuffy nose and restoring consciousness, functional components are stable, strong irritating odor can be retained for long time, the effect of restoring consciousness and relieving stuffy nose can be achieved, and practical popularization and application value is achieved.

Description

technical field [0001] The invention relates to an orifice-relieving and brain-invigorating composition and its preparation. Background technique [0002] Volatile oils of traditional Chinese medicines are a large class of transdermal absorption enhancers with excellent properties, which can promote the transdermal absorption of drugs and produce synergistic effects with transdermally absorbed drugs. However, volatile oils of traditional Chinese medicines have poor solubility and poor stability. In life, the volatile oil of traditional Chinese medicine is often made into external aromatic ointment due to its aromatic smell, which is used to treat symptoms of nasal congestion and dizziness. [0003] Nasal inhalation drug delivery is a kind of inhalation drug delivery system. The inhalation drug delivery system is a drug delivery method that combines aerosol technology with the anatomical, physiological and histological characteristics of the respiratory system to exert local ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/67A61P25/26A61K31/045
CPCA61K9/007A61K31/045A61K36/324A61K36/534A61K36/61A61K36/67A61K47/40A61P25/26A61K2300/00
Inventor 陈晓娜盛琳罗海燕娄晓雪金琴符华丽徐章升
Owner HAINAN MEDICAL COLLEGE
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