Method for preparing floating swimming micromachine

A technology of machines and metal balls, which is applied in the field of preparation of floating micromachines, can solve the problems of poor biocompatibility of chemical fuels, difficulty in applying to living organisms, and insufficient driving force of movement, etc., and achieve uniform size and non-toxicity Good, long storage time effect

Inactive Publication Date: 2019-11-26
HARBIN INST OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] The purpose of the present invention is to solve the problems in the above-mentioned prior art, that is, the swimming micromachines driven by air bubbles have poor chemical fuel biocompatibility, harsh exercise conditions, complicated preparation, difficult to apply in vivo, and the exercise time Short, follow-up movement driving force is insufficient, etc., and then provide a preparation method and application of floating micromachines

Method used

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  • Method for preparing floating swimming micromachine
  • Method for preparing floating swimming micromachine
  • Method for preparing floating swimming micromachine

Examples

Experimental program
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Effect test

Embodiment 1

[0026] Embodiment one: if Figure 1-5 Shown, the preparation method of a kind of floating swimming micromachine involved in this embodiment, the optimum scheme of this method:

[0027] Step 1: Wash the magnesium spheres with an average size of 10 μm with acetone, isopropanol and ethanol three times respectively.

[0028] Step 2: Disperse the cleaned magnesium balls into water, drop a solution containing metal balls at a concentration of 2mg / ml on the glass slide with a pipette gun, and then dry it on a slope with an inclination angle of 45 degrees.

[0029] Step 3: Decorate gold with a thickness of 10 nm on the surface of the glass sheet by electron beam evaporation.

[0030] Step 4: Spray the polyethylene terephthalate onto the surface of the glass sheet.

[0031] Step 5: The metal balls are separated from the surface of the glass sheet by ultrasonic or mechanical means, then added to the gelatin solution, and the solution is slowly heated to 60°C.

[0032] Step 6: Inject ...

Embodiment 2

[0038] Embodiment two: if figure 2 Shown, the application of the preparation method of a kind of floating swimming micromachine involved in this embodiment, figure 2 The direction of the middle arrow is the movement direction of the floating robot. Putting the prepared floating micromachine into the water can control the movement direction and speed of the floating micromachine in the water. The movement mode in the water is driven by air bubbles.

Embodiment 3

[0039] Embodiment three: as Figure 3-5 As shown, the preparation method and application of a kind of floating and swimming micromachine involved in this embodiment, the time series photos of the photoacoustic imaging motion of the floating and swimming micromachine obtained in this test example are as follows image 3 shown, from image 3 It can be seen that this floating micromachine can move upwards in water driven by air bubbles.

[0040] The scanning electron micrograph of the floating micromachine that this test example obtains is as follows: Figure 4 As shown, the diameter of the floating and swimming micromachines is 10-20 μm, and the surface modification of the floating and swimming micromachines has the characteristics of asymmetric distribution.

[0041] The floating and swimming micromachine obtained in this test example is placed in a salt solution to adjust the pH value to realize the movement of the swimming machine.

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Abstract

The invention provides a method for preparing a floating swimming micromachine, and belongs to the technical field of preparation of self-driven micromachines and application of self-driven micromachines. The method for preparing the floating swimming micromachine comprises the steps that 1, metal balls are pretreated; 2, the surfaces of the metal balls are coated with gold by an electronic beam evaporation method; 3, polyterephthalate is sprayed on the metal balls; 4, the metal balls are wrapped with gelatin; and 5, the outermost layers of the metal balls are modified with paraffin' the application of the method for preparing a floating swimming microcomputer of the present; according to the application of the method for preparing the floating swimming micromachine, the floating swimmingmicromachine is put into water, self-driven movement of the floating swimming micromachine can be achieved by bubble driving, the movement conditions are easy to meet, the preparation is simple, and experiment repeatability is high; and the prepared floating swimming micromachine has wide application prospects in the field of biomedicine.

Description

technical field [0001] The invention relates to a preparation method and application of a floating micromachine, and belongs to the technical field of preparation of a self-driven micromachine and application of the self-driven micromachine. Background technique [0002] Swimming micromachines made of different materials are a hot field of nanoscience in recent years, and the materials used to make them determine their different movement modes and mechanisms. The driving mechanism of existing swimming micromachines can be divided into bubble driving, self-electrophoresis, diffusion electrophoresis and so on. Hydrogen peroxide is the most widely used fuel among the fuels used in the bubble drive of swimming micromachines. However, as a fuel, hydrogen peroxide has poor biocompatibility and certain toxicity, so it cannot be used in organisms, so there is an urgent need for an alternative fuel with low toxicity to organisms and good biocompatibility for potential biomedical app...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M37/00B22F1/00B22F1/02B82Y5/00B82Y40/00C23C14/16C23C14/24
CPCA61M37/00B82Y5/00B82Y40/00C23C14/16C23C14/24A61M2207/00B22F1/102B22F1/17
Inventor 王金梦吴志光贺强
Owner HARBIN INST OF TECH
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