New application of fibrinogen gamma chain in the field of tooth regeneration and its kit

A technology of fibrinogen and kits, which is applied in the direction of peptide/protein components, medical preparations containing active ingredients, drug combinations, etc., can solve the problems of undisclosed application of fibrinogen γ chains, etc., and achieve significant tooth regeneration, The effect of improving efficiency
CN110664993BActive Publication Date: 2020-09-29NANFANG HOSPITAL OF SOUTHERN MEDICAL UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
NANFANG HOSPITAL OF SOUTHERN MEDICAL UNIV
Publication Date
2020-09-29

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Abstract

The invention discloses an application of a fibrinogen gamma chain as a dental pulp dentin regeneration reagent, and provides a kit for promoting dental pulp dentin regeneration. The kit comprises thefibrinogen gamma chain as a growth factor for promoting odontoblast differentiation of dental pulp stem cells, can significantly improve an efficiency of the dentin differentiation of the dental pulpstem cells, provides a new method for promoting dental pulp dentin regeneration, and has a significant tooth regeneration effect.
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Description

technical field

[0001] The invention belongs to the application field of biological reagents, and in particular relates to the application field of new uses of proteogen cells. Background technique

[0002] Pulp and periapical infection is one of the most common clinical diseases in the oral cavity, and root canal therapy is a routine treatment for infected pulp in clinical practice. Despite its satisfactory clinical efficacy in terms of infection control and pain relief, traditional treatment modalities only seal the space of the root canal system without restoring original pulp tissue function and vitality. Without the blood, nerve and nutritional support provided by the pulp tissue, teeth after root canal treatment are more prone to various complications such as crown discoloration, root fracture and reinfection. Long-term studies have shown that the rate of tooth loss after root canal treatment is much higher than that of untreated teeth. Therefore, it is an urgent cli...

Claims

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