Full-automatic full-closed multi-target nucleic acid detection device

Abstract

The invention discloses a full-automatic full-closed multi-target nucleic acid detection device. The full-automatic full-closed multi-target nucleic acid detection device comprises a card box, a cardbox heater, a transmission structure and a barcode reader, wherein the card box comprises a box body; a sample inlet is formed in the top of the box body, a seal cover is arranged at the sample inlet,and the seal cover and the box body are in magnetic adsorption through a magnetic part; the bottom of the box body is provided with a sample pool, a reagent bin and a hybrid tank; a chip is arrangedat the bottom of the hybrid tank, and is provided with a detection probe which can be specifically hybridized with a PCR product; a sampling needle is arranged in the box body; the card box heater isprovided with a nucleic acid extraction magnet; the transmission structure is used for controlling the sampling needle to move in the box body; the card box is inserted into an instrument and is identified through the barcode reader, and analysis results are directly gathered into a computer. The technical scheme aims at realizing extraction, amplification and detection into a whole, is full automatic, full closed and pollution-proof, and enables the connection of the seal cover to be firm.

Description

technical field [0001] The invention relates to the technical field of nucleic acid detection, in particular to a fully automatic fully enclosed multi-target nucleic acid detection device. Background technique [0002] There are three main steps in molecular diagnostics: nucleic acid extraction, amplification, and detection. There are many methods for each step, each method has different reagents to choose from, and each method has some manufacturers that have produced different automated instruments. Therefore, a challenge for clinical users is how to select and integrate these Reagents and instruments, so that each step has the most optimized results. [0003] An optimal molecular differential diagnosis solution should be: extraction, amplification, detection, trinity; fully automatic, fully enclosed, anti-pollution, triathlon. The necessity of amplification: the purpose of amplification is to increase the signal-to-noise ratio. All diagnostics seek the best signal-to-n...

AI Technical Summary

Problems solved by technology

Solving the problem of pollution not only reassures users, but also solves the problems of space shortage and high infrastructure costs for grassroots hospitals

At the same time, the sealing cover of the injection port of the existing box body still has the problems of being relatively easy to lose and not being securely connected.

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