SNP loci related to spleen weight on chromosome 6 of meat Simmental cattle and its application
A technology of Simmental cattle and chromosomes, which is applied in the direction of recombinant DNA technology, microbial measurement/inspection, DNA/RNA fragments, etc., can solve the problems of large confidence region and limit the application of molecular markers for complex traits, so as to improve spleen weight, The effect of increasing market competitiveness
Active Publication Date: 2021-05-18
INST OF ANIMAL SCI OF CHINESE ACAD OF AGRI SCI
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Problems solved by technology
Although the candidate gene method has the advantages of simple method and convenient operation, it can only target genes with known biological functions; while the confidence region of the candidate gene identified by the QTL mapping method is also large, which greatly limits the ability of complex trait molecules Application of markers in livestock genetics and breeding
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[0021]1, experimental animals
[0022]The experimental cattle population of the present invention is from the Inner Mongolian Xilin Gol League Ulagu Management District Ranch, China Meat, Ximen Tariu 1093, which is the meat of the Chinese Academy of Agricultural Sciences Beijing Animal Husbandry and Veterinary Research Institute, Simmental Cow resource population.
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Abstract
The present invention provides the SNP site on chromosome 6 of meat Simmental cattle related to spleen weight and its application. The site of the SNP marker is the 38852378th nucleoside on chromosome 6 of UMD3.1 version of the international bovine reference genome Acid site, the base of this site is G or A. By optimizing the dominant allele of the SNP, the invention can increase the frequency of the dominant allele generation by generation, increase the spleen weight of meat Simmental cattle, accelerate the progress of cattle genetic improvement, and effectively improve the economic benefits of beef cattle breeding.
Description
Technical field[0001]The present invention relates to the SNP site and application of the meat in chromosome and spleen heavy correlation.Background technique[0002]Meat Siemetal Cattle is the most popular cattle of China. It has the characteristics of fast growth, high productivity, so it is often used as terminal parent in breeding production. The spleen is often used as Chinese medicine in China. Currently, the breeding of meat Simmental cattle is mainly based on increasing the growth of the product, the growth rate, etc., and the breeding of the spleen is concerned. In addition, the spleen weight is subject to a number of genetically controlled mass control, and there is a large number of quantative trait loci, qtls thereof. Therefore, it is difficult to rapidly improve the breeding progress of the target traits using conventional breeding methods. The rapid development of molecular marking technology provides possible selection for this type of character.[0003]In the past, it wa...
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Patent Type & Authority Patents(China)
IPC IPC(8): C12Q1/6888C12N15/11
CPCC12Q1/6888C12Q2600/124C12Q2600/156C12Q2600/172
Inventor 朱波刘影李俊雅徐玲庄站伟徐凌洋张路培高会江高雪陈燕蔡文涛
Owner INST OF ANIMAL SCI OF CHINESE ACAD OF AGRI SCI
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