Solid-state fermented traditional Chinese medicinal additive with function of preventing and controlling parasites of livestock and poultry

A solid-state fermentation and parasite technology, applied in anti-infective drugs, drug combinations, pharmaceutical formulations, etc., can solve the problems of poor treatment effect, high toxicity of livestock and poultry, and many drug residues, and achieve short production cycle and high bioavailability. , the effect of easy absorption

Inactive Publication Date: 2020-05-08
六安恒佳生物科技有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to provide a solid-state fermentation traditional Chinese medicine additive for the prevention and control of livestock and poultry parasites, which solves the problems of high toxicity to livestock and poultry, many drug residues, high drug resistance and poor therapeutic effect of existing antiparasitic drugs

Method used

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  • Solid-state fermented traditional Chinese medicinal additive with function of preventing and controlling parasites of livestock and poultry
  • Solid-state fermented traditional Chinese medicinal additive with function of preventing and controlling parasites of livestock and poultry
  • Solid-state fermented traditional Chinese medicinal additive with function of preventing and controlling parasites of livestock and poultry

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Embodiment 1

[0034] This embodiment provides a solid-state fermentation traditional Chinese medicine additive for preventing and controlling livestock and poultry parasites, which is made by the following preparation method:

[0035] S1: In parts by weight, take 35 parts of Sophora flavescens extract, 30 parts of capillary extract, 30 parts of Agrimony extract, 30 parts of Changshan extract, 25 parts of Guanzhong extract, 25 parts of betel nut extract, 25 parts of extract, 20 parts of pumpkin seed extract and 20 parts of licorice extract form a mixed powder;

[0036]S2: after mixing the mixed powder and fermentation medium, inoculate probiotics, and ferment for 36 hours at 36°C-38°C, pressure 0.05kPa, stirring speed 20r / min, pH value 6.5, Obtain a liquid traditional Chinese medicine fermentation mixture, spray and dry it at 60°C to obtain a fermentation mixture powder; wherein, the addition ratio of the mixture powder to the fermentation medium is 15g:1L;

[0037] S3: Packing the solid fe...

Embodiment 2

[0044] This embodiment provides a solid-state fermentation traditional Chinese medicine additive for preventing and controlling livestock and poultry parasites, which is made by the following preparation method:

[0045] S1: In parts by weight, take 30 parts of Sophora flavescens extract, 35 parts of capillary extract, 25 parts of Agrimony extract, 35 parts of Changshan extract, 20 parts of Guanzhong extract, 30 parts of betel nut extract, 20 parts of extract, 25 parts of pumpkin seed extract and 15 parts of licorice extract form a mixed powder;

[0046] S2: after mixing the mixed powder and fermentation medium, inoculate probiotics, and ferment for 48 hours at 36°C-38°C, pressure 0.02kPa, stirring speed 30r / min, pH value 6.0, Obtain a liquid traditional Chinese medicine fermentation mixture, spray and dry it at 50°C to obtain a fermentation mixture powder; wherein, the addition ratio of the mixture powder to the fermentation medium is 20g:1L;

[0047] S3: Packing the solid f...

Embodiment 3

[0054] This embodiment provides a solid-state fermentation traditional Chinese medicine additive for preventing and controlling livestock and poultry parasites, which is made by the following preparation method:

[0055] S1: In parts by weight, take 40 parts of Sophora flavescens extract, 25 parts of capillary extract, 35 parts of Agrimony extract, 25 parts of Changshan extract, 30 parts of Guanzhong extract, 20 parts of betel nut extract, Torreya chinensis 30 parts of extract, 15 parts of pumpkin seed extract and 25 parts of licorice extract form a mixed powder;

[0056] S2: after mixing the mixed powder and fermentation medium, inoculate probiotics, and ferment for 24 hours at 36°C-38°C, pressure 0.1kPa, stirring speed 10r / min, pH value 7.0, The liquid traditional Chinese medicine fermentation mixture was obtained, and sprayed and dried at 65°C to obtain the fermentation mixture powder; wherein, the addition ratio of the mixture powder to the fermentation medium was 8g:1L; ...

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Abstract

The invention discloses a solid-state fermented traditional Chinese medicinal additive with a function of preventing and controlling parasites of livestock and poultry and belongs to the technical field of fermented traditional Chinese medicinal additives. A preparation method of the solid-state fermented traditional Chinese medicinal additive comprises the following steps: preparing mixed powderfrom a sophora flavescens extract, a capillary wormwood herb extract, a hairyvein agrimonia herb extract, an antifeverile dichros extract, a rhizoma dryopteris extract, an areca nut extract, a torreyanucifera extract, a pumpkin seed extract and a licorice root extract; uniformly mixing the mixed powder with a fermentation medium, inoculating the mixture with probiotics, and performing fermentation and spray-drying to obtain fermented mixture powder; and performing package and warehousing. According to the preparation method, the traditional Chinese medicinal extracts are used as fermenting raw materials, intermediate substances are biologically transformed by utilizing optimized saccharomyces cerevisiae and bacillus licheniformis, the traditional microecological preparation with no toxicity, no residue, environmental friendliness, easy absorption and remarkably enhanced antibacterial activity is prepared, and the medicinal effect is remarkably improved.

Description

technical field [0001] The invention relates to the technical field of fermented traditional Chinese medicine additives, in particular to a solid-state fermented traditional Chinese medicine additive for preventing and controlling livestock and poultry parasites. Background technique [0002] Livestock and poultry parasitic diseases are diseases caused by various pathogenic parasites that parasitize animals, livestock and poultry. Including: ①Diseases caused by worms parasitic on livestock and poultry are called helminthiasis. Fasciolasis, gastrointestinal nematodes, taeniasis, syphilis, cysticercosis (commonly known as rice star meat) and pulmonary filariasis often occur in cattle and sheep. ②External parasites mainly refer to some insects, such as mosquitoes, sandflies, lice, fleas, ticks, etc. When these insects sting and suck blood, they come into contact with the host's body surface, and then leave after sucking blood. ③Diseases caused by protozoa parasitic on livest...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/889A61P33/02A61P33/10A61P33/14A61K35/742
CPCA61K35/742A61K36/064A61K36/12A61K36/13A61K36/185A61K36/282A61K36/42A61K36/484A61K36/489A61K36/73A61K36/889A61K2236/19A61P33/02A61P33/10A61P33/14A61K2300/00
Inventor 王学善
Owner 六安恒佳生物科技有限公司
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