Deep eutectic solvent and method for extracting flavone di-C-glycoside from premna fulva

Abstract

The invention discloses a deep eutectic solvent and a method for extracting flavone di-C-glycoside from premna fulva. The deep eutectic solvent consists of choline chloride and any one of 1,3-propylene glycol, levulinic acid, glycollic acid and DL-lactic acid in a mole ratio of 1:(1-3). The method for extracting flavone di-C-glycoside from premna fulva comprises a step of obtaining a premna fulvaextracting solution, namely by taking premna fulva as a raw material, performing extraction by using a mixture consisting of the deep eutectic solvent and water, performing solid-liquid separation, and collecting a liquid, namely the premna fulva extracting solution, wherein the volume ratio of the deep eutectic solvent to the water is (2-4):1. Compared with the prior art, the deep eutectic solvent disclosed by the invention is not only convenient to prepare, but also capable of efficiently and selectively extracting five main flavone di-C-glycoside compounds in a premna fulva plant, and compared with a conventional organic solvent, namely ethanol, the deep eutectic solvent has greatly improved extraction efficiency, in addition, is small in environment protection toxicity, and greatly reduces damage to human bodies and the environment.

Description

Technical field [0001] The invention relates to a deep eutectic solvent and a method for extracting flavone diglycoside from war bones, and belongs to the technical field of chemical extraction. Background technique [0002] Zhangu, a plant of the Verbenaceae family Premna fulva Craib, also known as Tubawang and Chuanyunjian. Its dried stems are commonly used in folk to treat low back pain, bruises and sprains, rheumatoid arthritis and rheumatoid arthritis, liver area Pain, etc., are authentic medicinal materials in Guangxi. At present, many Zhangu related products have been developed, such as Jiangu injection (such as the invention patent with publication number CN1098004A), compound Zhangu liniment (Pan Hongping, the experimental research on skin irritation of compound Zhangu liniment. Chinese Journal of Traditional Chinese Medicine, 2005(08):625-626.). [0003] The existing solvents for extracting battle bones are mostly concentrated in 20-70% ethanol (for example, 20% ethanol...

AI Technical Summary

Problems solved by technology

As an extraction solvent, ethanol is volatile and causes potential safety hazards, and the use of low-concentration ethanol will lead to high recovery costs and serious waste

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