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A traditional Chinese medicine compound for treating primary Sjögren's syndrome and its preparation method and application

A Sjögren's syndrome, primary technology, applied in pharmaceutical formulations, medical preparations containing active ingredients, antipyretics, etc., can solve problems such as difficulty in obtaining satisfactory curative effects

Active Publication Date: 2021-09-14
JIANGSU PROVINCIAL HOSPITAL OF TCM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is still no specific drug for the treatment of SS, and it is difficult to obtain satisfactory curative effect by simply starting with nourishing yin and moistening dryness.

Method used

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  • A traditional Chinese medicine compound for treating primary Sjögren's syndrome and its preparation method and application
  • A traditional Chinese medicine compound for treating primary Sjögren's syndrome and its preparation method and application
  • A traditional Chinese medicine compound for treating primary Sjögren's syndrome and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] 1. A traditional Chinese medicine compound for preventing and treating primary Sjögren's syndrome, which comprises the following raw materials in parts by mass:

[0030] Pseudostellaria 10g, red dates 5g, roasted licorice 3g, cinnamon twigs 5g, white peony root 10g, Cimicifuga 3g, raw Atractylodes macrocephala 10g, dendrobium 10g, ebony plum 10g, lily 30g, light bamboo leaves 10g, anemarrhena 10g, red peony root 10g, Lulu Pass 10g.

[0031] 2, a kind of preparation method with the Chinese medicine compound prescription of prevention and treatment of primary Sjögren's syndrome of the present invention, it comprises the following steps:

[0032] According to the number of parts by mass, take 10g of heterophylla, 5g of red dates, 3g of roasted licorice, 5g of cassia twig, 10g of white peony root, 3g of Cimicifuga, 10g of raw Atractylodes macrocephala, 10g of dendrobium, 10g of black plum, 25g of lily, 10g of light bamboo leaves, 10g of anemarrhena, Paeoniae 10g, Passepart...

Embodiment 2

[0034] Take the extract prepared in the above Example 1, add cornstarch and lubricant magnesium stearate, mix evenly, granulate, and then compress into tablets to make tablets.

Embodiment 3

[0036] 1. A traditional Chinese medicine compound for preventing and treating primary Sjögren's syndrome, which comprises the following raw materials in parts by mass:

[0037] 5 parts of heterophylla, 3 parts of red dates, 1 part of roasted licorice, 3 parts of cassia twig, 5 parts of white peony root, 1 part of cohosh, 5 parts of raw Atractylodes rhizome, 5 parts of dendrobium, 5 parts of ebony plum, 15 parts of lily, 5 parts of light bamboo leaves , 5 copies of Anemarrhena, 5 copies of Chishao, and 5 copies of Passepartout.

[0038] 2, a kind of preparation method with the Chinese medicine compound prescription of prevention and treatment of primary Sjögren's syndrome of the present invention, it comprises the following steps:

[0039] (1) Take 5 parts of heterophylla, 3 parts of red dates, 1 part of roasted licorice, 3 parts of cassia twig, 5 parts of white peony, 1 part of Cimicifuga, 5 parts of raw Atractylodes macrocephala, 5 parts of dendrobium, 5 parts of dark plum, 15...

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Abstract

The invention discloses a compound traditional Chinese medicine for preventing and treating primary Sjögren's syndrome and its preparation method and application. Lily, light bamboo leaves, Anemarrhena, red peony and Passepartout. The present invention screens through a large number of experiments, adopts syndrome differentiation and treatment of traditional Chinese medicine to select raw material composition and dosage ratio scientifically, each component can coordinate with each other and promote each other, and has a synergistic effect, and has a good effect of invigorating the spleen and replenishing qi. The effect of nourishing yin and moisturizing dryness, promoting blood circulation and dredging collaterals can not only improve symptoms such as dry mouth and eyes, muscle and joint pain, and fatigue in patients with primary Sjogren's syndrome, but also have obvious effects in increasing saliva flow and tear flow, and can effectively control the development of the disease , and no obvious adverse reactions, has achieved good technical progress.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine compound, and in particular relates to a traditional Chinese medicine compound capable of preventing and treating primary Sjögren's syndrome, a preparation method and application thereof. Background technique [0002] Sjogren's syndrome ( Syndrome (SS) is a chronic autoimmune disease, second only to rheumatoid arthritis (RA), characterized by dry mouth mainly caused by salivary gland and lacrimal gland dysfunction , dry eye symptoms and possible systemic multi-organ manifestations, divided into primary Sjogren's syndrome (primary syndrome, pSS) and secondary Sjogren's syndrome (Secondary syndrome, sSS), the incidence is mostly middle-aged and elderly women. Dryness, fatigue, and pain are major factors reducing quality of life in patients with pSS, which is generally considered a chronic, non-life-threatening disease in the lay medical setting, but with multisystem invol...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61P37/02A61P29/00A61P1/02A61P27/02
CPCA61K36/185A61K36/284A61K36/36A61K36/484A61K36/54A61K36/65A61K36/71A61K36/725A61K36/736A61K36/8964A61K36/8967A61K36/8984A61K36/899A61K2236/331A61K2236/333A61K2236/39A61P1/02A61P27/02A61P29/00A61P37/02A61K2300/00
Inventor 何晓瑾金实王瑞瑞印秀珉
Owner JIANGSU PROVINCIAL HOSPITAL OF TCM
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