Spectinomycin hydrochloride soluble powder capable of being directly dissolved in oil seedlings and preparation method thereof
A guanlincomycin and soluble technology, which is applied in medical preparations with non-active ingredients, medical preparations containing active ingredients, powder delivery, etc., can solve the problems of low bioavailability, high cost of use, poor dissolution effect, etc. problem, to achieve the effect of improving potency, reducing use cost and simplifying operation
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Embodiment 1
[0023]
[0024] Preparation:
[0025] Mix sodium lauryl sulfate and sodium stearate with anhydrous glucose according to the formula ratio, crush them and pass through a No. 5 sieve, weigh them for later use; mix cholesterol, lecithin and cocoa butter according to the formula ratio, fully After grinding, pass through a No. 5 sieve, and weigh for later use; weigh spectinomycin hydrochloride, lincomycin hydrochloride, and astragalus polysaccharide, and crushed and sieved sodium lauryl sulfate, sodium stearate, anhydrous glucose and ground, The sieved cholesterol, lecithin and cocoa butter are uniformly mixed by a three-dimensional mixer to obtain the product.
Embodiment 2
[0027]
[0028]
[0029] Preparation:
[0030] Mix Poloxamer 188, sodium stearate and anhydrous glucose according to the formula ratio, crush them and pass through a No. 5 sieve, and weigh them for later use; mix cholesterol, lanolin and cocoa butter After grinding, pass through a No. 5 sieve, and weigh for later use; weigh spectinomycin hydrochloride, lincomycin hydrochloride, soybean polysaccharide, and crushed and sieved Poloxamer 188, sodium stearate, anhydrous glucose and ground , and the sieved cholesterol, lanolin and cocoa butter are evenly mixed by a three-dimensional mixer to obtain the product.
Embodiment 3
[0032]
[0033] Preparation:
[0034] Mix sodium stearate with anhydrous glucose according to the formula ratio, crush it and pass it through a No. 5 sieve, and weigh it for later use; mix cholesterol, lecithin and cocoa butter according to the formula ratio, grind it in a mortar and pass it through a No. 5 sieve , weighed for later use; Weigh spectinomycin hydrochloride, lincomycin hydrochloride, soybean polysaccharide, astragalus polysaccharide, and crushed and sieved sodium stearate and anhydrous glucose as well as ground and sieved cholesterol, egg Phospholipids and cocoa butter are uniformly mixed by a three-dimensional mixer to obtain the product.
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