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Application of angstrom silver antiviral solution in the preparation of anti-covid-19 virus medicine

A COVID-19, anti-virus technology, applied in the field of medicine, can solve problems such as femoral head necrosis, and achieve the effect of simple process, simple preparation process and strong anti-virus ability

Active Publication Date: 2022-03-18
SHENZHEN AMCAN MEDICAL BIOTECH LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is currently no effective antiviral drug, and high-dose hormone therapy has the risk of inducing severe sequelae such as femoral head necrosis. Some new antiviral drugs and vaccines also require a long period of research and development and clinical trials

Method used

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  • Application of angstrom silver antiviral solution in the preparation of anti-covid-19 virus medicine
  • Application of angstrom silver antiviral solution in the preparation of anti-covid-19 virus medicine
  • Application of angstrom silver antiviral solution in the preparation of anti-covid-19 virus medicine

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0029] Fruit-free sugar is medicinal fruit-free sugar. Angstrom silver material is made of metal silver and other silver-containing compounds by physical or chemical methods. The particle size is mostly below 100 angstroms, so it is called For emmy silver. Obtaining flow process is roughly as follows: Angstrom silver of the present invention, its preparation method comprises the following steps:

[0030] (1) Fill the explosion chamber with inert gas argon to keep the air pressure in the explosion chamber at 1×10 6 Pa, and stabilize the working temperature at 8-12°C.

[0031] (2) Continuously push a silver wire with a diameter of 0.5mm and a length of 8-12cm into the explosion chamber. When the silver wire contacts the positive plate, a high voltage of 25kV is generated, causing the silver wire to explode and instantly evaporate the silver wire into silver. vapor plasma.

[0032] (3) The silver vapor accompanied by argon gas is pumped into the quenching chamber whose tempera...

Embodiment 1

[0037] An angstrom silver antiviral solution of the present invention comprises: 0.5g / L angstrom level elemental silver powder; 5g / L medicinal fruit sugar-free; 994.5g / L high-purity distilled water. Its preparation method comprises the following steps:

[0038] (1) Be that 1~30Ang angstrom level elemental silver powder is added to high-purity distilled water by particle diameter, obtain the concentration and be the angstrom silver solution of 0.5g / L.

[0039] (2) The angstrom silver solution obtained in step (1) was ultrasonically dispersed using an ultrasonic oscillator, the ultrasonic power was 5KW, the frequency was 60KHz, and the dispersion time was 60s to obtain the angstrom silver dispersion.

[0040] (3) Add fructose in the angstrom silver dispersion, so that the fructose concentration is 5g / L, use an ultrasonic oscillator to carry out ultrasonic dispersion, the ultrasonic power is 15KW, the frequency is 150KHz, and the time is 20s; obtain the angstrom silver dispersion...

Embodiment 2

[0043] The application of the angstrom silver antiviral solution of a kind of embodiment 1 in anti-COVID-19 virus, its application method is:

[0044] (1) Grouping:

[0045] Control group: distilled water;

[0046] Angstrom silver antiviral solution group 1: 1ng / μL Angstrom silver antiviral solution;

[0047] Angstrom silver antiviral solution group 2: 5ng / μL Angstrom silver antiviral solution;

[0048] Angstrom silver antiviral solution group three: 10ng / μL Angstrom silver antiviral solution.

[0049] (2) After stably culturing Vero cells, infect the cells with SARS-CoV-2 virus. The infected cells were divided into four groups, and the distilled water, medium containing 1ng / μL, 5ng / μL and 10ng / μL of Angstrom silver antiviral solution were replaced in each group, and after continuous culture for 48h, RT-qPCR The replication rate of SARS-CoV-2 virus in the collected samples was detected by the method; the cytotoxicity was detected by the CCK-8 kit.

[0050] (3) Results:

[...

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Abstract

The invention discloses the application of an angstrom silver antiviral solution in the preparation of anti-COVID-19 virus medicine. The angstrom silver antiviral solution includes angstrom silver simple substance, no fruit sugar and distilled water, and the concentration of angstrom silver simple substance is 0.5 ~1.0g / L; the concentration of fructose is 5.0~10.0g / L. The angstrom silver antiviral solution of the present invention has an inhibitory effect on the COVID-19 virus, and can be applied to the preparation of anti-COVID-19 virus medicaments.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to the application of an angstrom silver antiviral solution in the preparation of anti-COVID-19 virus drugs. Background technique [0002] The COVID-19 virus belongs to the genus Beta coronavirus, which has an envelope, and the particles are round or oval, generally pleomorphic, with a diameter of about 60 to 140 nanometers. When isolated and cultured in vitro, the COVID-19 virus can be found in human respiratory epithelial cells in about 96 hours. [0003] The source of infection seen so far is mainly COVID-19 infected patients, and asymptomatic infected persons may also be contagious. Transmission through respiratory droplets and close contact is the main route of transmission. Its incubation period is 1-14 days. With fever, dry cough. Fatigue is the main manifestation. A small number of patients are accompanied by symptoms such as nasal congestion, runny nose, sore throat, ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/08A61K33/38A61K47/26A61P31/14
CPCA61K33/38A61K9/08A61K47/26A61P31/14
Inventor 谢辉张文艳司徒伟怡王振兴陈春媛王杨
Owner SHENZHEN AMCAN MEDICAL BIOTECH LTD
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