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Rhizoma atractylis lancea and hyperforin perforatum mixed extract as well as preparation method and application thereof

A Hypericum perforatum, mixed extraction technology, applied in the field of daily chemicals, to achieve the effect of controlling excessive secretion, gentle on the skin, and improving the removal of mites

Active Publication Date: 2020-08-07
广州智尚生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the prior art, there is little research on the inhibitory effect of the mixed extract of Atractylodes atractylodes root and Hypericum perforatum on chitinase, so as to achieve the effect of removing mites

Method used

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  • Rhizoma atractylis lancea and hyperforin perforatum mixed extract as well as preparation method and application thereof
  • Rhizoma atractylis lancea and hyperforin perforatum mixed extract as well as preparation method and application thereof

Examples

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Effect test

Embodiment 1

[0029] The preparation method of the mixed extract of Atractylodes atractylodes Rhizome and Hypericum perforatum in this embodiment comprises the following steps:

[0030] (1) Raw material pretreatment: clean the roots of Atractylodes atractylodis and Hypericum perforatum respectively, drain off the water, dry, pulverize and pass through an 80-mesh sieve, and mix them according to the mass ratio of 3:1 for later use;

[0031] (2) Enzymolysis: the mixed powder in step (1) is added to the aqueous solution according to the ratio of material to liquid 1g:15mL, then a compound enzyme is added to carry out enzymolysis, the weight of the added compound enzyme is 0.5% of the weight of the mixed powder, and after the enzyme is eliminated, it is obtained enzymatic solution;

[0032] The compound enzyme is composed of cellulase and glucoamylase in a mass ratio of 4:1, wherein the enzyme activity of cellulase is 70,000 U / g, and the enzyme activity of glucoamylase is 50,000 U / g; the enzyme...

Embodiment 2

[0040] The preparation method of the mixed extract of Atractylodes atractylodes Rhizome and Hypericum perforatum in this embodiment comprises the following steps:

[0041] (1) Raw material pretreatment: clean the roots of Atractylodes atractylodis and Hypericum perforatum respectively, drain off the water, dry, pulverize and pass through a 100-mesh sieve, and mix them according to the mass ratio of 5:1 for later use;

[0042] (2) Enzymolysis: add the mixed powder in step (1) to the aqueous solution according to the ratio of material to liquid 1g:20mL, then add the compound enzyme to carry out enzymolysis, the weight of the added compound enzyme is 0.5% of the weight of the mixed powder, after the enzyme is eliminated, the obtained enzymatic solution;

[0043] The compound enzyme is composed of cellulase and glucoamylase in a mass ratio of 2:1, wherein the enzyme activity of cellulase is 70,000 U / g, and the enzyme activity of glucoamylase is 50,000 U / g; the enzyme The hydrolys...

Embodiment 3

[0051] The preparation method of the mixed extract of Atractylodes atractylodes Rhizome and Hypericum perforatum in this embodiment comprises the following steps:

[0052] (1) Raw material pretreatment: clean the roots of Atractylodes atractylodis and Hypericum perforatum respectively, drain off the water, dry, pulverize and pass through a 120-mesh sieve, and mix them according to the mass ratio of 9:1 for later use;

[0053] (2) Enzymolysis: Add the mixed powder in step (1) to the aqueous solution according to the ratio of material to liquid 1g:25mL, then add the compound enzyme for enzymolysis, the weight of the added compound enzyme is 0.5% of the weight of the mixed powder, and get enzymatic solution;

[0054] The compound enzyme is composed of cellulase and glucoamylase in a mass ratio of 5:1, wherein the enzyme activity of cellulase is 70,000 U / g, and the enzyme activity of glucoamylase is 50,000 U / g; the enzyme The hydrolysis conditions are: enzymatic hydrolysis for 1....

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Abstract

The invention discloses a mixed extract of rhizoma atractylodis lancea and hyperforin perforatum as well as a preparation method and application of the mixed extract. The method comprises: (1) raw material pretreatment; (2) enzymolysis; (3) high-pressure homogeneous extraction; (4) concentrating; (5) purification. The rhizoma atractylodis lancea and hyperforin perforatum mixed extract contains bioactive molecules, can effectively inhibit the biological activity of chitinase, achieves good acarus killing and inhibiting effects, and is mild and non-irritant to the skin. When the acaricide is applied to daily chemicals, skin acarid breeding can be prevented, symptoms such as pruritus, acne and epifolliculitis caused by acarid of the skin can be improved, and the healthy skin state can be recovered.

Description

technical field [0001] The invention relates to the technical field of daily chemicals, in particular to a mixed extract of Atractylodes atractylodis root and Hypericum perforatum and its preparation method and application. Background technique [0002] Demodex is a kind of small permanent parasitic mite that parasitizes in the hair follicles and sebaceous glands of humans and mammals. It is mainly divided into two types: Demodex follicularis and Demodex sebaceousis. It causes local itching, pityriasis pilaris, blepharitis, seborrheic dermatitis, etc., and is closely related to rosacea, acne, boils and other diseases, endangering skin health and mental health. With the improvement of living standards, people pay more and more attention to facial beauty and mental health issues, and the prevention and treatment of facial demodicosis has gradually become a public health problem to be solved urgently. And judging from the domestic anti-mite skin care products market in recent ...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61K8/04A61Q19/10A61Q19/00A61Q17/02A61Q17/00A61K36/634A61P17/00A61P17/04A61P17/10A61P33/14
CPCA61K8/9789A61K8/042A61Q19/00A61Q17/02A61Q17/005A61Q19/008A61Q19/10A61K36/284A61K36/634A61P17/10A61P33/14A61P17/04A61P17/00A61K2800/5922A61K2800/10A61K2800/805A61K2800/782A61K2300/00Y02A50/30
Inventor 龙君杨思敏王猛
Owner 广州智尚生物科技有限公司
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