Bifidobacterium lactis Probio-M8 capable of relieving and treating coronary heart disease and application of bifidobacterium lactis Probio-M8

A technology for Bifidobacterium lactis and coronary heart disease, applied in the field of microorganisms, can solve the problems of lack of can effectively relieve and treat coronary heart disease anxiety and depression, and achieve the effect of lowering cholesterol levels, huge application prospects, and reducing anxiety.

Pending Publication Date: 2020-08-28
BEIJING SCITOP BIO TECH CO LTD
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The embodiment of the present application provides a strain of Bifidobacterium lactis Probio-M8 that can alleviate and treat coronary heart disease and its application to solve the problem of lack of probiotics that can effectively alleviate and treat coronary heart disease, improve patient anxiety and depression, and lower cholesterol levels question

Method used

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  • Bifidobacterium lactis Probio-M8 capable of relieving and treating coronary heart disease and application of bifidobacterium lactis Probio-M8
  • Bifidobacterium lactis Probio-M8 capable of relieving and treating coronary heart disease and application of bifidobacterium lactis Probio-M8
  • Bifidobacterium lactis Probio-M8 capable of relieving and treating coronary heart disease and application of bifidobacterium lactis Probio-M8

Examples

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Effect test

experiment example 1

[0068] Experimental example 1 Clinical trial of treating coronary heart disease with Bifidobacterium lactis Probio-M8

[0069] The human trial of Bifidobacterium lactis Probio-M8 in the treatment of coronary heart disease was carried out for 6 months, and 60 volunteers were recruited. The test was divided into a probiotic group and a placebo group. The probiotic group took basic treatment drugs for coronary heart disease (aspirin, statins, metoprolol, isosorbide dinitrate, etc.) + Bifidobacterium lactis Probio-M8 (3.00 ×10 10 CFU / day), the placebo group took basic drugs for the treatment of coronary heart disease (aspirin, statin lipid-lowering drugs, metoprolol, isosorbide dinitrate, etc.) + placebo.

[0070] Clinical data include anxiety and depression survey, angina pectoris survey and six blood indicators of low-density lipoprotein cholesterol, serum interleukin-6, alanine aminotransferase, blood urea nitrogen, creatinine and white blood cell count. Clinical data were ...

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Abstract

The invention discloses bifidobacterium lactis Probio-M8 capable of relieving and treating coronary heart disease and application of the bifidobacterium lactis Probio-M8. Clinical population tests indicate that the bifidobacterium lactis Probio-M8 is good in safety, and can reduce anxiety and depressive emotions of patients with coronary heart disease, relieve angina pectoris symptoms of the patients and reduce the content of low-density lipoprotein cholesterol in blood. The bifidobacterium lactis Probio-M8 has obvious effects of relieving and treating the coronary heart disease and anxiety and reducing cholesterol level, and has a huge application prospect in preparation of products and functional products for relieving and treating the coronary heart disease.

Description

technical field [0001] The application relates to the technical field of microorganisms, in particular to a strain of Bifidobacterium lactis Probio-M8 capable of alleviating and treating coronary heart disease and its application. Background technique [0002] Coronary atherosclerotic heart disease, referred to as coronary heart disease, is one of the common causes of death in cardiovascular diseases. As the incidence of coronary heart disease continues to increase worldwide, the research on its pathogenesis and treatment measures has become more and more in-depth. Hyperlipidemia, characterized by high levels of total cholesterol, triglycerides, and low-density lipoproteins, and low levels of high-density lipoproteins, leads to atherosclerosis, which in turn leads to coronary heart disease. Usually, patients with recessive coronary heart disease or coronary heart disease have ups and downs in mood, and mild depression or anxiety are common. In the occurrence and developmen...

Claims

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Application Information

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IPC IPC(8): A23L29/00A23L33/135A23L2/39A23G3/36A23L11/00A23C9/123A23L19/00A61K35/745A61P9/10A61P3/06A61P25/22A61P25/24C12N1/20C12R1/01A23L11/50
CPCA23L29/065A23L33/135A23L2/39A23G3/366A23C9/1234A23L19/00C12N1/20A61K35/745A61P9/10A61P3/06A61P25/22A61P25/24A23V2002/00A23L11/50C12R2001/01C12N1/205A23V2400/531A23V2200/30A23V2200/3262
Inventor 刘晓军马杰张凌宇张建军其木格苏都杨慧娟
Owner BEIJING SCITOP BIO TECH CO LTD
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