3 results about "Low cholesterol levels" patented technology

The invention relates to the technical field of molecular breeding, and discloses a molecular marker related to the LDL-C level of porcine serum, a detection reagent and a breeding method. The invention also discloses a primer group for identifying the molecular marker, and the primer group is used for amplifying the following SNP sites: SNP01, which are obtained on the basis of a pig reference genome Sscrofa11.1 and are positioned on 112bp, 008bp and 261bp of a third chromosome, and the genotype is A / G; sNP02 is located at 112bp, 008bp and 354 bp of a third chromosome, and the genotype of SNP02 is A / G; sNP03 is located at 112bp, 008bp and 583bp of the third chromosome, and the genotype of SNP03 is A / G. The primer group for identifying the molecular marker can quickly and effectively identify the LDL-C level of pig serum, and is used for assisting in breeding pig strains with low cholesterol or specific lipid metabolism characteristics.

The present invention relates to a composition for preventing, alleviating or treating metabolic diseases, the composition comprising a rosuvastatin and ursodeoxycholic acid conjugate or a pharmaceutically acceptable salt thereof, in which the statin conjugates to an ursodeoxycholic acid transporter and has the effects of function inhibition, cholesterol level reduction, antilipid toxicity, body weight reduction, blood lipid reduction, fatty liver alleviation, inflammation alleviation, and kidney damage alleviation. The composition, in the form of a single formulation, has the characteristics of maintaining the therapeutic effects of rosuvastatin and ursodeoxycholic acid while reducing the side effects of existing statins, and thus can be widely used as a substitute for complex formulations in the treatment of metabolic diseases.

The present application relates to the technical field of bioengineering, and particularly relates to a kind of extraction method of Panax quinquefolium seed natural oil body and application thereof.The method comprises the following steps: after Panax quinquefolium seed is crushed, it is mixed with buffer solution to obtain homogenate liquid; the homogenate liquid is subjected to solid-liquid separation, and filtrate is collected; the filtrate is subjected to high-speed centrifugation under low-temperature conditions, and upper oil body phase is collected, to obtain Panax quinquefolium seed natural oil body. 16 kinds of fatty acid compositions in the Panax quinquefolium seed oil body are identified by GC-MS system, and it is found that the proportion of unsaturated fatty acids is extremely high, wherein the content of linoleic acid is as high as 76.34%, and the Panax quinquefolium seed oil body is rich in polyunsaturated fatty acids such as gamma-linolenic acid, alpha-linolenic acid and arachidonic acid, and no trans fatty acids and short-chain saturated fatty acids are detected. The characteristics make it have multiple nutritional functions such as regulating lipid metabolism, reducing cholesterol and antioxidant, and have broad prospects for developing high-nutrition edible oil or functional food additive.