The invention provides a self-heal health-care oral solution capable of reducing blood fat, which comprises the following raw medicines in parts by weight: 10-50 parts of self-heal, 10-20 parts of cape jasmine, 10-20 parts of pollen typhae, 10-20 parts of purslane, 10-20 parts of rehmannia root, 10-20 parts of baikal skullcap root, 10-20 parts of kudzu root, 10-20 parts of gynostemma pentaphylla, 10-20 parts of sophora fruit, 10-20 parts of dried orange peel, 10-20 parts of corn silk, 10-20 parts of oriental wormwood, 10-20 parts of hawthorn, 10-20 parts of trichosanthes root, 10-20 parts of burdock fruit, 10-20 parts of lysimachia, 10-20 parts of tribulus terrestris, 10-20 parts of oldenlandia and 10-20 parts of centella. The oral solution provided by the invention is capable of preventing absorption of cholic acid or cholesterol from the intestinal tract, promoting cholic acid or cholesterol to be discharged with feces, inhibiting in vivo synthesis of cholesterol, or promoting conversion of cholesterol, promoting LDL receptor expression on a cell membrane, and accelerating lipoprotein decomposition.