A pharmaceutical composition for preventing and treating sequelae of deep vein thrombosis of lower extremities, its preparation method and application

Abstract

The invention provides a pharmaceutical composition for preventing and treating sequelae of deep vein thrombosis of lower extremities, a preparation method and application thereof, and belongs to the field of traditional Chinese medicines. The pharmaceutical composition is a preparation prepared from raw materials in the following weight proportions: 30-50 parts of astragalus, 5-20 parts of peach kernel, 5-20 parts of safflower, 10-20 parts of Chuanxiong, and 10-20 parts of angelica tail , 10-20 parts of Radix Paeoniae Rubra, 20-40 parts of Motherwort, 10-30 parts of Poria Cocos, 10-20 parts of Cortex Moutan, 10-30 parts of Salvia Miltiorrhiza, 10-20 parts of Clematis, 5-10 parts of Notopterygium, 1-10 parts of Leech 10 parts, 1-10 parts of Panax notoginseng, 10-30 parts of Codonopsis pilosula, 10-20 parts of Atractylodes macrocephala. The medicines in the composition are properly compatible, can replenish qi, activate blood circulation, and clear channels, and can effectively treat the sequelae of deep vein thrombosis of the lower extremities. The drug has little damage to the liver and kidney, and the incidence of adverse reactions is low, so it can be used for long-term treatment. The invention adopts pills to prepare, which is more convenient for decocting and carrying, and is beneficial to long-term taking, and the pills are milder in nature and better in safety.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a pharmaceutical composition for preventing and treating sequelae of deep vein thrombosis of lower extremities, a preparation method and application thereof. Background technique [0002] Lower extremity deep venous thrombosis (LDVT, also known as lower extremity deep venous thrombosis) is a common clinical disease, which belongs to the category of "joint swelling" in traditional Chinese medicine, major surgery, trauma, long-term bed rest, limb immobilization, etc. are common Predisposing factors can lead to pulmonary embolism, post-thrombotic syndrome, seriously affect the quality of life of patients, and even lead to death. The disease is divided into acute phase (within 14 days), protracted phase (14 days to March) and sequelae phase (after 3 months). The treatment of this disease is currently mainly focused on the acute phase and the persistent phase,...

AI Technical Summary

Problems solved by technology

Although this formula nourishes qi and activates blood circulation, its main effect is to prevent postoperative deep vein thrombosis of the lower extremities, and there is no support for its application in the sequelae of deep vein thrombosis of the lower extremities; at the same time, from the perspective of compatibility, it is combined with Coptis chinensis, Cortex Phellodendron, Honeysuckle, and Papaya and other heat-clearing and damp-damp drugs, and occupy a certain proportion of the original prescription, the medicinal properties are slightly cold and cool, and are more suitable for people with qi deficiency and blood stasis, and dampness and heat, but not completely suitable for all patients with thrombosis

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