Pharmaceutical composition for preventing and treating sequela stage of lower extremity deep venous thrombosis as well as preparation method and use of pharmaceutical composition

Abstract

The invention provides a pharmaceutical composition for preventing and treating a sequela stage of lower extremity deep venous thrombosis as well as a preparation method and use of the pharmaceuticalcomposition, and belongs to the traditional Chinese medicine field. The pharmaceutical composition is a preparation prepared from the following raw material drugs in parts by weight: 30-50 parts of radix astragali, 5-20 parts of semen persicae, 5-20 parts of safflower carthamus, 10-20 parts of rhizoma chuanxiong, 10-20 parts of radix angelicae sinensis, 10-20 parts of radix paeoniae rubra, 20-40 parts of herba leonuri, 10-30 parts of poria cocos, 10-20 parts of cortex moutan, 10-30 parts of radix salviae miltiorrhizae, 10-20 parts of radix clematidis, 5-10 parts of angelica polyclada, 1-10 parts of hirudo, 1-10 parts of pseudo-ginseng, 10-30 parts of radix codonopsis and 10-20 parts of rhizoma atractylodis macrocephalae. The compatibility of the components of the composition is precise andproper, the composition is capable of benefiting vital energy, activating blood circulation, dredging channels of arteries and veins and effectively treating the sequela stage of the lower extremitydeep venous thrombosis, the effects of the composition are equal to the effects of a clinical common Western medicine, namely Rivaroxaban, and the cost of the composition is lower than that of the Rivaroxaban; and meanwhile, the composition has little injury to livers and kidneys, is low in occurrence rate of adverse reactions and can be applied to long-term treatment. The pharmaceutical composition is prepared into a pill, is convenient to decoct and carry, is suitable for long-term drinking, and the pill has a relatively gentle property and relatively good safety.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a pharmaceutical composition for preventing and treating sequelae of deep vein thrombosis of lower extremities, a preparation method and application thereof. Background technique [0002] Lower extremity deep venous thrombosis (LDVT, also known as lower extremity deep venous thrombosis) is a common clinical disease, which belongs to the category of "joint swelling" in traditional Chinese medicine, major surgery, trauma, long-term bed rest, limb immobilization, etc. are common Predisposing factors can lead to pulmonary embolism, post-thrombotic syndrome, seriously affect the quality of life of patients, and even lead to death. The disease is divided into acute phase (within 14 days), protracted phase (14 days to March) and sequelae phase (after 3 months). The treatment of this disease is currently mainly focused on the acute phase and the persistent phase,...

AI Technical Summary

Problems solved by technology

Although this formula nourishes qi and activates blood circulation, its main effect is to prevent postoperative deep vein thrombosis of the lower extremities, and there is no support for its application in the sequelae of deep vein thrombosis of the lower extremities; at the same time, from the perspective of compatibility, it is combined with Coptis chinensis, Cortex Phellodendron, Honeysuckle, and Papaya and other heat-clearing and damp-damp drugs, and occupy a certain proportion of the original prescription, the medicinal properties are slightly cold and cool, and are more suitable for people with qi deficiency and blood stasis, and dampness and heat, but not completely suitable for all patients with thrombosis

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