Medicinal and edible composition for improving age-related macular degeneration and preparation method and application of medicinal and edible composition

A dual-use technology for macular degeneration, medicine and food, applied in the direction of medical preparations containing active ingredients, drug combinations, applications, etc., to achieve the effects of protecting retinal damage, increasing expression, and protecting from damage

Active Publication Date: 2020-09-15
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For wet AMD, clinically, the American Association of Ophthalmology (AAO) 2019 AMD clinical guidelines recommend the use of anti-vascular endothelial growth factor (VEGF) drugs (Ranibizumab, Aflibercept, Brolucizumab) for intravitreal injection as the first-line treatment; For the treatment of dry AMD, there is no clinically approved drug in the world

Method used

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  • Medicinal and edible composition for improving age-related macular degeneration and preparation method and application of medicinal and edible composition
  • Medicinal and edible composition for improving age-related macular degeneration and preparation method and application of medicinal and edible composition
  • Medicinal and edible composition for improving age-related macular degeneration and preparation method and application of medicinal and edible composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Example 1 A method for preparing a medicinal and edible composition for improving age-related macular degeneration, comprising the following steps:

[0037] (1) Take 1 part of medlar, 2 parts of hawthorn, 2 parts of astragalus, 1 part of Yizhiren, 2 parts of Dendrobium candidum, 2 parts of oyster, and 1 part of chrysanthemum, and mix them. Add water in an amount 8 times the weight of the medicinal material, reflux for extraction for 120 minutes, filter, and collect the filtrate and filter residue.

[0038] (2) Take the medicinal dregs in step (1), add water with a volume 10 times the weight of the medicinal material, extract under reflux for 120 minutes, filter, and collect the filtrate.

[0039] (3) Merge the filtrate obtained in step (1) and step (2), concentrate under reduced pressure to obtain extract, add 0.01 part of grape seed proanthocyanidin, 0.01 part of lutein, and 0.01 part of taurine, and prepare the extract under low temperature and reduced pressure .

Embodiment 2

[0040] Example 2 A method for preparing a medicinal and edible composition for improving age-related macular degeneration, comprising the following steps:

[0041] (1) Take 4 parts of medlar, 7 parts of hawthorn, 7 parts of astragalus, 4 parts of Yizhiren, 4 parts of Dendrobium candidum, 9 parts of oyster, and 4 parts of chrysanthemum, and mix them. Add water in an amount 8 times the weight of the medicinal material, reflux for extraction for 120 minutes, filter, and collect the filtrate and filter residue.

[0042] (2) Take the medicinal dregs in step (1), add water with a volume 10 times the weight of the medicinal material, extract under reflux for 120 minutes, filter, and collect the filtrate.

[0043] (3) Merge the filtrate obtained in step (1) and step (2), concentrate under reduced pressure to obtain extract, add 0.08 part of grape seed proanthocyanidin, 0.08 part of lutein, and 0.08 part of taurine, and prepare the extract under low temperature and reduced pressure . ...

Embodiment 3

[0044] Example 3 A method for preparing a medicinal and edible composition for improving age-related macular degeneration, comprising the following steps:

[0045] (1) Take 3 parts of medlar, 6 parts of hawthorn, 6 parts of astragalus, 3 parts of Yizhiren, 3 parts of Dendrobium candidum, 8 parts of oyster, and 3 parts of chrysanthemum, and mix them. Add water in an amount 8 times the weight of the medicinal material, reflux for extraction for 120 minutes, filter, and collect the filtrate and filter residue.

[0046] (2) Take the medicinal dregs in step (1), add water with a volume 10 times the weight of the medicinal material, extract under reflux for 120 minutes, filter, and collect the filtrate.

[0047] (3) Merge the filtrate obtained in step (1) and step (2), concentrate under reduced pressure to obtain extract, add 0.05 part of grape seed proanthocyanidin, 0.05 part of lutein, and 0.05 part of taurine, and prepare the extract under low temperature and reduced pressure . ...

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Abstract

The invention discloses a medicinal and edible composition for improving age-related macular degeneration and a preparation method and application of the medicinal and edible composition. The medicinal and edible composition is prepared from the raw materials in parts by weight: 1-5 parts of fructus lycii, 4-8 parts of fructus crataegi, 4-8 parts of radix astragali, 1-5 parts of fructus alpiniae oxyphyllae, 1-5 parts of dendrobium officinale, 5-10 parts of oysters, 1-5 parts of chrysanthemum flowers, 0.01-0.1 part of grape seed procyanidine, 0.01-0.1 part of xanthophyll and 0.01-0.1 part of taurine. The medicinal and edible composition can improve age-related macular degeneration, is good in safety and can be used for preparing common food or healthcare products or medicines for improvingage-related macular degeneration.

Description

technical field [0001] The invention relates to a medicinal and edible composition, in particular to a medicinal and edible composition capable of improving age-related macular degeneration and its preparation method and application. Background technique [0002] Various sources show that China has entered an aging society and is developing at an accelerated pace. China's existing elderly population has exceeded 160 million, and the number is increasing at a rate of nearly 8 million every year. It is estimated that by 2050, China's elderly population will reach one-third of the total population. With the rapid increase of the elderly population, especially the average annual growth rate of 1 million elderly people over 80 years old and the disabled elderly, the demand for life care, rehabilitation care, medical care, spiritual culture, etc. of the elderly has become increasingly prominent, and the problem of providing for the aged has become increasingly severe . [0003]...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9062A61P27/02A61P39/06A23L33/00A61K35/618A61K31/352A61K31/047A61K31/185
CPCA23V2002/00A61K31/047A61K31/185A61K31/352A61K35/618A61K36/287A61K36/481A61K36/734A61K36/815A61K36/8984A61K36/9062A61K2236/331A61K2236/39A61K2236/51A23L33/00A61P27/02A61P39/06A61K2300/00A23V2250/21A23V2200/318A23V2250/2042
Inventor 段金廒朱悦郭盛钱大玮
Owner NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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