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Application of sinomenine hydrochloride to preparation of drug for treating pain caused by rib fracture

A technology for sinomenine hydrochloride and rib fracture, applied in the field of medicine, can solve problems such as many adverse reactions, and achieve the effects of less adverse reactions, good therapeutic effect and simple operation

Pending Publication Date: 2020-09-18
通道侗族自治县民族中医医院
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The invention provides an application of sinomenine hydrochloride in the preparation of medicines for treating rib fracture pain, so as to solve the problem of many adverse reactions of existing painkillers in treating rib fracture pain

Method used

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  • Application of sinomenine hydrochloride to preparation of drug for treating pain caused by rib fracture
  • Application of sinomenine hydrochloride to preparation of drug for treating pain caused by rib fracture

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0022] The following takes the rib fracture cases of 30 cases in the Department of Orthopedics and Traumatology of a certain hospital as a case to describe the therapeutic effect of sinomenine hydrochloride in the present application.

[0023] 1. Case source

[0024] 30 cases of patients with rib fractures, aged 35-55 years, with a course of 2h-3d, admitted to the Department of Orthopedics and Traumatology of a traditional Chinese medicine hospital from October 2018 to March 2020; among them, there were 23 male patients and 7 female patients, all without other diseases .

[0025] 2. Diagnostic criteria

[0026] The patient had a clear history of chest trauma, local swelling, pain, tenderness after injury, increased pain after speaking loudly, coughing, sneezing or activities, and a positive chest squeeze test. Chinese name: computerized tomography) examination, a rib fracture was clearly diagnosed, and the fracture location and displacement were checked according to CT, as a...

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Abstract

The present invention provides an application of sinomenine hydrochloride to the preparation of a drug for treating pain caused by rib fracture. The sinomenine hydrochloride may be used for preparingthe drug for treating pain caused by rib fracture. Compared with an opioid drug, a general anesthesia drug and a non-steroidal pain relieving drug, the sinomenine hydrochloride provided by the presentapplication has fewer adverse reactions. Compared with a method such as an intravenous injection method or a whole-body oral administration method, a local ashi-point injection method is higher in local drug concentration and better in pain relieving effect; and the sinomenine hydrochloride has a better treatment effect clinically in combination with an acupoint effect while taking a drug effect.The sinomenine hydrochloride provided by the present application is simple and convenient to operate due to no need of help from other people or equipment and instruments during treatment.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to the application of sinomenine hydrochloride in the preparation of medicine for treating rib fracture pain. Background technique [0002] There are 12 pairs of ribs in the human body, which are divided equally on both sides of the chest. They are connected with the sternum and thoracic vertebrae to form a complete thorax. Under the action of external violence, the ribs of the human body will be fractured, and the fracture ends will be broken inward, causing damage to the internal organs of the chest. Because of the support of the upper and lower ribs and intercostal muscles at both ends of the rib fracture, dislocation or movement after the fracture is rare, and most of them can heal automatically. However, rib fractures can irritate the intercostal nerves, resulting in chest pain, especially with deep breathing, coughing, or turning, which seriously affects quality of life. In...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/485A61K45/06A61K31/167A61P29/00A61P19/08
CPCA61K31/485A61K45/06A61K31/167A61P29/00A61P19/08A61K2300/00
Inventor 周松成
Owner 通道侗族自治县民族中医医院
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