Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A kind of emulsion with hair growth effect and preparation method thereof

A technology of emulsion and efficacy, applied in the field of emulsion with hair growth effect and its preparation, can solve the problems of poor transdermal absorption, large solubility difference, low utilization rate of active ingredients, etc., and achieve high transdermal absorption rate and hair growth effect Obvious and safe effect

Active Publication Date: 2022-01-14
PROYA COSMETICS
View PDF5 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the solubility of each component varies greatly. Ligusticum chuanxiong oil and tocopheryl nicotinate are oil-soluble components, while glucosyl rutin, epigallocatechin gallate glucoside, and diglucosyl gallic acid are water-soluble components. Stable complex cannot be obtained by mixing, and the transdermal absorption is poor when used directly, resulting in low utilization rate of active ingredients and difficulty in exerting hair growth effect

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of emulsion with hair growth effect and preparation method thereof
  • A kind of emulsion with hair growth effect and preparation method thereof
  • A kind of emulsion with hair growth effect and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0058] Embodiment 1: A kind of preparation method of bicontinuous phase liquid crystal emulsion with hair growth effect, adopts the following steps:

[0059] 步骤1:按质量比3:1:1:0.5:0.5称取川芎油、葡糖基芦丁、生育酚烟酸酯、表棓儿茶酚棓酸葡糖苷、二葡糖基棓酸,混合 later as a hair growth active substance;

[0060] Step 2: Weigh according to the following mass ratio: 5% hair growth active substance obtained in step 1, 30% PEG-8 glyceryl isostearate, 5% PEG-7 glyceryl cocoate, 1% cetearyl alcohol, 20%鲸蜡醇乙基己酸酯、8%丁二醇、5%双丙甘醇、26%去离子水;

[0061] Step 3: Mix the hair growth actives described in step 2, PEG-8 glyceryl isostearate, PEG-7 glyceryl cocoate, cetearyl alcohol, and cetyl ethyl hexanoate, and heat to 60°C, as the initial oil phase; mix butylene glycol, dipropylene glycol, and deionized water evenly, and heat to 60°C, as the initial water phase;

[0062] Step 4. Slowly add the initial water phase obtained in step 3 into the initial oil phase described in step 3, and stir while adding dropwise, the dropping speed is 5ml / mi...

Embodiment 2

[0065] A preparation method of a bicontinuous phase liquid crystal emulsion with hair growth effect, adopts the following steps:

[0066] Step 1: Weigh Chuanxiong oil, glucosyl rutin, tocopheryl nicotinate, epigallocatechin gallic acid glucoside, diglucosyl gallic acid according to the mass ratio of 2:1:1:0.3:0.3, mix 后作为生发活性物;

[0067] Step 2: Weigh according to the following mass ratio: 10% hair growth active substance obtained in step 1, 20% PEG-8 glyceryl isostearate, 20% PEG-7 glyceryl cocoate, 2% cetearyl alcohol, 18% Cetyl Ethylhexanoate, 3% Butylene Glycol, 6% Glycerin, 21% Deionized Water;

[0068] Step 3: Mix the hair growth actives described in step 2, PEG-8 glyceryl isostearate, PEG-7 glyceryl cocoate, cetearyl alcohol, and cetyl ethyl hexanoate, and heat to 70°C, as the initial oil phase; mix butylene glycol, glycerin, and deionized water evenly, and heat to 70°C, as the initial water phase;

[0069] 步骤4、将步骤3所得初始水相缓慢滴加到步骤3所述初始油相中,边滴加边搅拌,滴加速度1ml / min,搅拌速度为600rpm,温...

Embodiment 3

[0072] A preparation method of a bicontinuous phase liquid crystal emulsion with hair growth effect, adopts the following steps:

[0073] 步骤1:按质量比6:1:1:0.5:0.5称取川芎油、葡糖基芦丁、生育酚烟酸酯、表棓儿茶酚棓酸葡糖苷、二葡糖基棓酸,混合 later as a hair growth active substance;

[0074] 步骤2:按以下质量比称取:10%步骤1所得生发活性物、5% PEG-8 甘油异硬脂酸酯、30%PEG-7 甘油椰油酸酯、1%鲸蜡硬脂醇、 15% Cetyl Ethylhexanoate, 5% Dipropylene Glycol, 4% Propylene Glycol, 30% Deionized Water;

[0075] 步骤3:将步骤2所述生发活性物、PEG-8 甘油异硬脂酸酯、PEG-7 甘油椰油酸酯、鲸蜡硬脂醇、鲸蜡醇乙基己酸酯混合均匀,加热至 72°C, as the initial oil phase; mix dipropylene glycol, propylene glycol, and deionized water evenly, and heat to 72°C, as the initial water phase;

[0076] 步骤4、将步骤3所得初始水相缓慢滴加到步骤3所述初始油相中,边滴加边搅拌,滴加速度2ml / min,搅拌速度为300rpm,温度保持在72℃,得到双连续相微乳液;

[0077] 步骤5:将步骤4所得双连续相微乳液,以25000rpm速度均质5分钟,再利用循环砂磨机研磨1小时,所述循环砂磨机选用1mm锆珠、装填量为容腔体积的60 %, cooled to room temperature to obtain a bicontinuous phase emulsion containing liquid crystal structure with an average particle size of 75nm.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to an emulsion with hair growth effect and a preparation method thereof, which is characterized in that: it contains 0.5-10% mass fraction of hair growth active substances, and the hair growth active substances are composed of Chuanxiong oil, glucosyl rutin, and tocopherol nicotinic acid The ester, epigallocatechin gallate glucoside, and diglucosyl gallate are composed in a mass ratio of 2-6:1:1:0.1-0.5:0.1-0.5. The invention has the characteristics of good stability, high transdermal absorption rate, good safety and obvious hair growth effect.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to an emulsion with hair growth effect and a preparation method thereof. Background technique [0002] The advancement of science and technology and the development of economy have accelerated the pace of our life. Factors such as increasing competitive pressure, environmental pollution, irregular life, and changes in eating habits have made the rate of hair loss continue to rise, so hair growth products have always had huge demand and development prospects. Seborrheic alopecia is a common disease in dermatology, androgen secretion disorder, excessive sebum secretion, causing blockage of hair follicles, insufficient blood supply to dermal papilla, nutritional deficiencies, metabolic disorders, leading to necrosis of hair follicles, and microbial infection will accelerate the process of hair loss. Among the commercially available hair growth products, hair growth ingredients such ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/92A61K8/60A61K8/67A61K8/02A61K8/06A61P17/14A61Q7/00
CPCA61K8/922A61K8/602A61K8/678A61K8/0295A61K8/06A61Q7/00A61P17/14A61K2800/5922A61K2800/592
Inventor 李昊李欣航杨盼盼薛绘韩丹吕旭阳蒋丽刚
Owner PROYA COSMETICS
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com