A composition for use in the treatment of conditions caused by calcium deficiency

A composition and calcium deficiency technology, applied in drug combination, drug delivery, bone diseases, etc., can solve the problem of inoperable calcium and vitamin D supplementation

Pending Publication Date: 2020-12-11
艾匹赛特制药公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, calcium and vitamin D supplementation through current regimens is inoperable

Method used

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  • A composition for use in the treatment of conditions caused by calcium deficiency
  • A composition for use in the treatment of conditions caused by calcium deficiency
  • A composition for use in the treatment of conditions caused by calcium deficiency

Examples

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Embodiment Construction

[0033] Certain exemplary embodiments will now be described to provide a thorough understanding of the principles and function of the invention. Those skilled in the art will appreciate that the described exemplary embodiments are non-limiting and that the scope of the invention is defined by the claims.

[0034] As indicated above, the present invention relates to compositions comprising

[0035] a) at least one bile acid or a salt thereof,

[0036] b) at least one fatty acid or a salt thereof,

[0037] c) calcium, and

[0038] d) Vitamin D.

[0039] The composition is intended for use as a medicine.

[0040] Surprisingly, it was observed according to the present invention that a composition comprising at least one bile acid or a salt thereof, at least one fatty acid or a salt thereof, vitamin D and calcium synergistically induces the expression of the vitamin D receptor coactivator Hsp90β.

[0041] By inducing the expression of vitamin D receptor coactivators, vitamin D-...

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PUM

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Abstract

The present invention is related to a composition comprising at least one bile acid; at least one fatty acid or salt thereof, calcium, and vitamin D, for use as a medicament, and especially in inducing expression of vitamin D-receptor co-activator Hsp90[beta] for increasing vitamin D-induced calcium uptake in a mammal. The invention is also related to a dietary or nutritional supplement comprisinga composition as described above and comprising additionally conventional components for dietary or nutritional supplements.

Description

technical field [0001] The present invention relates to compositions comprising at least one bile acid or a salt thereof, at least one fatty acid or a salt thereof. The composition may also comprise calcium and vitamin D and be used as a medicament, especially for the treatment and / or prophylaxis of conditions associated with insufficient intestinal calcium uptake. Background technique [0002] It has been calculated that the global obesity epidemic affected more than 1.5 billion people in 2003, and the global incidence is constantly increasing. Increased prevalence of obesity and obesity comorbidities (e.g. type 2 diabetes, hyperlipidemia, hypertension, ischemic heart disease, stroke, asthma, back and lower extremity joint degenerative problems, various cancers, depression etc.) associated with increased prevalence. Obesity is estimated to cause approximately 320 000 deaths per year in Western Europe. Thus, the loss of life expectancy due to obesity is profound. A 25-ye...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/567A61K31/19A61K31/593A61K33/06A61P19/00
CPCA61K31/19A61P19/00A61K33/06A61K45/06A61K31/592A61K31/201A61K31/575A61K2300/00A23L33/16A23L33/155A61K9/0019A61K9/0053
Inventor 拉尔斯·芬德里克斯维尔·瓦伦纽斯
Owner 艾匹赛特制药公司
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