25 results about "Calcium uptake" patented technology

The invention relates to the technical field of yoghourt preparation, in particular to normal-temperature cheese yoghourt capable of promoting calcium absorption and a preparation method of the normal-temperature cheese yoghourt. The normal-temperature cheese yoghurt mainly comprises the following raw materials in parts by weight: 60-70 parts of concentrated milk, 10-15 parts of distilled water, 5-10 parts of single cream, 2-10 parts of cream cheese, 2-10 parts of xylitol, 1-6 parts of starch, 0.1-0.5 part of tricalcium phosphate, 0-0.05 part of mogroside, 0.001-0.005 part of a leavening agent, 0.001-0.006 part of vitamin A and 0.001-0.006 part of vitamin D. The cheese yoghurt is reasonable in component matching, simple and stable in preparation process, free of preservatives and colloids, low in production cost and suitable for industrial production. The prepared product is uniform and stable, tastes fine and smooth, can be stably stored for a long time at normal temperature (at least 6 months at normal temperature), maximally retains the rich flavor and high nutrition density of cheese and the refreshing taste and digestibility of yoghourt, and meets the requirements of consumers on healthy, safe, delicious and convenient high-quality dairy products.

Disclosed in the present invention is a monodisperse nanocalcium carbonate-based foliar calcium fertilizer, comprising the following raw materials in parts by mass: 1-20 parts of a monodisperse nanocalcium carbonate filter cake, 0.05-0.9 parts of ethoxy-modified polytrisiloxane, 0.01-0.8 parts of modified casein, 0.01-0.8 parts of an enzyme, 0.05-0.9 parts of a sugar alcohol, and 10-180 parts of water. After being diluted by means of water such that the solid content of calcium carbonate is 0.5-2%, the foliar calcium fertilizer is used for foliar calcium supplementation of various crops and fruit and vegetable crops. The novel foliar calcium fertilizer is safe and non-toxic, can be directly sprayed onto foliar and fruit surfaces of crops and fruits and vegetables, effectively ensures calcium absorption and utilization in crops, achieves the effect of increasing yield and increasing income, and can also improve the yield of fruits and vegetables.

The invention belongs to the technical field of high-calcium dairy products, and particularly relates to low-sodium high-calcium long-term stable vitamin-containing cheese. The vitamin A and the vitamin D are added into the casein milk, calcium absorption and utilization are promoted, inorganic calcium salt does not need to be additionally added, the content of primary milk calcium is increased through a concentration technology, the high-calcium and low-sodium standard is achieved, and therefore the absorption advantage of the primary milk calcium is brought into play. Through improvement and deep coupling of three aspects of processes of secondary differential homogenization, steam direct injection instantaneous sterilization and reduced pressure flash evaporation, the shelf life, the stability and the flavor coordination of the plateau raw milk calcium cheese are obviously prolonged unexpectedly, and the product is good in fluidity and suitable for being sucked.

The invention discloses a cultivation method for enhancing the total amount of bio-available calcium of edible parts of pakchoi, and relates to the technical field of Chinese cabbage cultivation, and the method comprises the following steps: variety screening, seedling raising, transplanting, foliar fertilizer spraying, cultivation and picking. Through the design of high-calcium variety screening, calcium nutrition pretreatment in the seedling raising period, foliar calcium supplement and potassium fertilizer synergistic application, the calcium content of the edible part of the pakchoi is increased, more importantly, the absorption, transport and accumulation process of calcium in the plant body is optimized, the total amount of bio-available calcium which can be actually absorbed and utilized by the human body in the edible part is increased, and the yield of the pakchoi is increased. The problem that an existing calcium fertilizer application and biological enhancement technology cannot guarantee effective calcium absorption of a human body is solved. Aiming at the problems of low absorption efficiency of traditional soil calcium fertilizer application and lack of systematicness of a foliar calcium fertilizer technology, through pretreatment of an EDTA calcium complex in a seedling raising period, precipitation which is difficult to absorb and formed by combination of calcium and other substances in soil or a matrix is avoided, and an efficient calcium absorption basis is constructed for seedlings.

The invention discloses a preparation method of a high-absorptivity calcium supplement of vitamin D3 (VD3) and casein phosphopeptide chelated calcium (CPP-Ca), which comprises the following steps: firstly, dissolving casein phosphopeptide (CPP) in ultrapure water, adding calcium chloride, adjusting the pH value, stirring and reacting at a certain temperature to generate CPP-Ca, then precipitating by using ethanol, washing for multiple times to remove free calcium ions, and drying to obtain the high-absorptivity calcium supplement of vitamin D3 (VD3) and casein phosphopeptide chelated calcium (CPP-Ca). Centrifuging, collecting the precipitate, and freeze-drying to obtain purified CPP-Ca; the preparation method comprises the following steps: preparing CPP-Ca into a solution, adjusting the pH value, dropwise adding VD3 dissolved in ethanol into the solution, stirring and mixing at room temperature under a certain concentration to finally form the VD3 and CPP-Ca compound, and the compound prepared by the method can significantly promote calcium absorption and effectively improve the stability of VD3 and CPP.

The invention relates to the field of biological medicine, in particular to an endoplasmic reticulum targeting peptide, an agonist, a preparation method and application. Wherein the agonist comprises an endoplasmic reticulum targeting peptide, and further comprises a mitochondrial membrane disturbing sequence and a sequence with cathepsin B response, the mitochondrial membrane disturbing sequence is KLAKLAK 2, and the sequence with cathepsin B response is GFLG; the endoplasmic reticulum targeting peptide comprises a KKKAA peptide sequence, and chlorin e6 and R8 peptide are connected to the KKKAA peptide sequence; the mitochondrial membrane disturbing sequence is connected to the R8 peptide through a sequence with cathepsin B response. According to the scheme, the characteristics of biochemical information interaction and tumor growth regulation of the mitochondria and the endoplasmic reticulum are utilized, excessive stress of the endoplasmic reticulum and a mitochondria calcium uptake channel are activated at the same time in a safe and controllable mode, free Ca < 2 + > in the endoplasmic reticulum rapidly flows into the mitochondria, the steady states of the endoplasmic reticulum and the mitochondria of tumor cells are damaged, and the tumor growth is controlled. And the two synergistically induce cells to start an apoptosis procedure, so that the aim of treating diseases is fulfilled.

The invention belongs to the technical field of citrus reiculata Blanco planting, and particularly relates to a nanometer calcium fertilizer foliage application method for preventing sunburn and improving calcium absorption and coloring effects of citrus reiculata Blanco, which comprises the following steps: S1, selecting a citrus reiculata Blanco orchard, and performing ploughing, soil preparation, fertilization and watering by a conventional method; s2, adding 6-10 times by mass of clear water into the nano calcium carbonate fertilizer; s3, from June to August, uniformly spraying the nano calcium carbonate fertilizer solution to the fruit surfaces and the leaf surfaces of the citrus reiculata Blanco; and S4, other management is carried out according to a conventional method. Whole-plant spraying is adopted, the spraying period covers the whole summer high-temperature period, the sunburn fruit rate can be reduced, the yield can be increased, and normal growth of fruit trees is guaranteed; in addition, the calcium element of fruits can be supplemented, fruit dropping is reduced, the fruit value is improved, meanwhile, the peel brightness can be reduced, the red chromaticity is improved, and the fruit commodity value is improved. Therefore, the method has great application potential in expanding calcium fertilizer functions and improving citrus reiculata Blanco benefits.

This invention provides a nutritional composition rich in A2-β-casein that promotes calcium absorption, belonging to the field of functional foods. The invention obtains A2-β-casein through genotyping and purification, and then combines it with colostrum basic protein and a small amount of milk-derived calcium to form compositions with different ratios. This invention utilizes a Caco-2 cell model to study the fluorescence imaging of calcium ion influx into Caco-2 cells, the calcium absorption-promoting activity, and the absorption pathway, thereby comprehensively evaluating the calcium absorption characteristics of this composition and obtaining a nutritional composition rich in A2-β-casein that promotes calcium absorption.

This invention belongs to the field of biomedical and health care technology. Specifically, this invention relates to a composition of metabiotics and calcium salts and its application. Our unit unexpectedly discovered, through extensive research, that *Lactobacillus delbrueckii* subsp. bulgaricus Lb-87 (… Lactobacillus delbrueckii subsp. Bulgaricus Lb-87 (a metabiotic) can synergistically work with calcium salts to significantly improve the absorption rate of calcium ions in the body, thereby effectively promoting calcium utilization and maintaining normal physiological functions. This discovery provides a new technical path and solution for developing foods, pharmaceuticals, health foods, and dietary supplements with highly efficient calcium absorption-promoting functions and multiple effects.

The present application relates to a kind of ammonium chloride calcium stick, belong to the technical field of feed.The ammonium chloride calcium stick includes the following components: calcium chloride, calcium sulfate, ammonium chloride, vitamin B6, modified cysteine, syringaldehyde, vitamin D3, sodium tripolyphosphate and solvent.Sodium tripolyphosphate maintains the stability of vitamin D3 and vitamin B6, wherein vitamin B6 inhibits prolactin synthesis, vitamin D3 promotes calcium absorption, prevents low blood calcium and excessive mammary secretion.The present application modifies cysteine by eugenol, increases its stability and dispersibility, and forms electrostatic interaction with sodium tripolyphosphate, forms a stable crosslinking network structure, increases the binding force between the coating layer and the raw material, prevents the loss of effective dry milk ingredients, and achieves better dry milk effect.

Disclosed herein are micro-sized aragonite compositions and methods for enhancing calcium uptake and overall plant health. The disclosure provides calcium compositions comprising particles of aragonite, preferably oolitic aragonite, that are mechanically reduced to micron or sub-micron dimensions to generate a highly bioavailable, rapidly dissolving calcium source suitable for foliar or soil application. The compositions may be incorporated into liquid suspensions, granules, coated fertilizers, seed treatments, or nutrient delivery systems, and may optionally include biologically active agents, growth stimulants, humates, or surfactants to further promote uptake. Methods of using the compositions to treat calcium deficiency, strengthen cell walls, reduce blossom-end rot, increase stress tolerance, and improve yield are also provided.

The invention provides a nutrition preparation for promoting calcium absorption and a preparation method thereof. The nutrition preparation for promoting calcium absorption comprises the following raw materials: egg yolk frenum; the preparation method of the nutrition preparation for promoting calcium absorption comprises the following steps: S1, carrying out preheating treatment on a yolk frenum solution to obtain a preheated yolk frenum solution; the temperature of the preheating treatment is 52-58 DEG C; s2, mixing the preheated yolk lace solution with carboxymethyl cellulose to obtain a mixed solution; s3, adjusting the pH value of the mixed solution, and heating to obtain the nutrition preparation for promoting calcium absorption. The egg yolk frenum is applied to the nutrition preparation for promoting calcium absorption, so that calcium absorption can be remarkably promoted, and bones can be strengthened; the egg yolk lace solution is preheated and then mixed with carboxymethyl cellulose, and then the pH value is adjusted, so that the swallowing difficulty of the nutrition preparation for promoting calcium absorption can be reduced, a product with good uniformity and stability can be formed, and the effects of promoting calcium absorption and enhancing the mechanical property of bones can be guaranteed.

The invention belongs to the technical field of biological material preparation, and particularly discloses a mackerel tetrapeptide-calcium nano-composite as well as a preparation method and application thereof. The preparation method comprises the following steps: mixing mackerel flesh homogenate with an organic degreasing fluid, stirring in a constant-temperature water bath, carrying out suction filtration, air-drying and powdering to obtain mackerel protein powder; preparing a reaction solution, heating, cooling, preserving heat, carrying out alkaline enzymolysis, inactivating protease, centrifuging, taking supernatant, and freeze-drying to obtain lyophilized powder of the mackerel protein hydrolysate; identifying a polypeptide sequence, and screening a mackerel tetrapeptide amino acid sequence; the mackerel tetrapeptide is obtained by solid-phase synthesis of macromolecular resin and amino acid. The preparation method comprises the following steps: dissolving mackerel tetrapeptide in ultrapure water, adding a CaCl2 solution, heating under an alkaline condition, adding absolute ethyl alcohol, centrifuging and freeze-drying to obtain the mackerel tetrapeptide-calcium nanocomposite. The invention discloses a mackerel tetrapeptide-calcium nano-composite as well as a preparation method and application thereof. The mackerel tetrapeptide-calcium nano-composite has a self-assembly capability and a calcium absorption promoting effect.

The invention discloses a calcium formate and calcium carbonate compound feed additive as well as a preparation method and application thereof. Based on the total mass of the additive, the total mass content of calcium formate and calcium carbonate is not lower than 97%, and the balance is trace water and inevitable trace impurities. The mass of the calcium carbonate is 12%-16% of the mass of the calcium formate; the preparation method comprises the following steps: adding a certain amount of formic acid into a reaction tank; starting stirring, adding calcium carbonate into the formic acid, keeping the formic acid to be excessive, and fully reacting for 2-3 hours; adding excessive calcium hydroxide, and continuously reacting for 2-3 hours; putting the reaction liquid into a liquid storage tray, and standing until the reaction liquid is completely solidified; crushing and drying the solid product under carbon dioxide low-temperature airflow; and sieving the dried product to obtain the calcium formate and calcium carbonate compound feed additive. The feed additive disclosed by the invention is slowly dissolved in water, can effectively improve the palatability, and slowly releases formic acid in animal digestive tracts to achieve the effects of continuously inhibiting bacteria and promoting calcium absorption.

The invention discloses a pure steel calcium treatment spherical bomb feeding device which comprises a steel platform, a bomb dropping mechanism and a controller electrically connected with the bomb dropping mechanism, the steel platform is located above a steel ladle, a heat insulation fireproof layer is arranged at the lower end of the steel platform, and a plurality of vertical through holes which are distributed in rows and columns and used for allowing spherical bombs to pass through are formed in the steel platform; the horizontal positions of the vertical through holes are all within the range of the horizontal position of the inner ladle cavity of the steel ladle, and the bomb dropping mechanism is provided with a plurality of bomb dropping ends which are used for dropping bombs to the vertical through holes synchronously. According to the invention, after the bomb dropping mechanism is controlled, a plurality of spherical bombs are synchronously and uniformly dropped into a steel ladle through a plurality of vertical through holes which are distributed in rows and columns, so that the time of a calcium treatment process can be shortened, calcium absorption is promoted, and automation, high efficiency and large scale of calcium treatment can be realized; the heat insulation and fire prevention layer can insulate heat and prevent fire, so that the bomb dropping mechanism is not exposed in molten steel heat radiation baking any more, the bomb dropping mechanism does not deform for a long time, and then reliability is improved.

The invention discloses a layered slow-release composition for promoting calcium absorption and a preparation method thereof, and belongs to the technical field of food, the composition has a core-shell-suspension three-layer embedding structure: a core layer is an oil phase core formed by dissolving fat-soluble vitamins in caprylic and capric triglyceride; a shell layer is a compact protective film formed by Arabic gum on the surfaces of oil drops through interfacial polymerization, calcium ions are preferentially adsorbed through electrostatic interaction to form a Ca < 2 + >-COO <-> complexing layer, and the calcium ions are prevented from migrating into an oil phase; the suspension layer is of a three-dimensional network structure synergistically constructed by xanthan gum and natural pectin in a fruit concentrated solution, the composition realizes spatial isolation and sequential release of vitamins and calcium, the vitamins are quickly released in the gastrointestinal tract 15 minutes before, the calcium is slowly released in 30-60 minutes, the vitamin D can play a role in promoting calcium absorption only after being activated, and the vitamin D can play a role in promoting calcium absorption after being activated. The vitamin D of the composition is released in advance and activates calcium binding protein in intestinal tracts, preparation is made for calcium absorption, the bioavailability of the vitamin D is improved by 35-45%, and the calcium absorption rate reaches 45-52%.

The invention discloses an application of a calcium-reinforced layered network structure emulsion in preparation of a product for promoting calcium absorption and enhancing bone mineral density, and aims to solve the technical bottlenecks of low absorption rate and insufficient bone targeting of a traditional calcium supplement. According to the emulsion, the insoluble calcium salt is uniformly dispersed in an oil phase by utilizing the density difference between the insoluble calcium salt and the oil phase, and is embedded into a layered network structure formed by proteoglycan. Hydrophobic molecules or hydrophobic chain segments spontaneously gather to form a hydrophobic region, and free diffusion of water molecules and water-soluble ions is effectively prevented, so that solubilization and stable dispersion of insoluble calcium salt are realized. The obtained emulsion has good processing stability and tolerance, the absorption rate of calcium is remarkably improved, and the bone mineral density is favorably enhanced. The system can be used as a calcium fortifying preparation to realize on-line addition, the process is simple and convenient, the system is suitable for various foods such as dairy products, biscuits, ice cream and plant milk, and preparation and application of high-calcium nutritious foods are realized.

Methods and compositions use a galactooligosaccharide (GOS) for increasing absorption of calcium, such as calcium naturally present in ingredients of the composition and / or present in a food product, a meal or a diet, wherein the food product, meal or diet is combined with the composition and / or consumed separately from the composition. Some embodiments are directed to a milk-based composition comprising calcium intrinsically present in the milk, further comprising milk protein, and further comprising a mixture of lactose, glucose, galactose and the galactooligosaccharide (GOS). In some embodiments, the milk-based composition does not contain exogeneous calcium, such that the only calcium in the composition is the calcium intrinsically present in the milk.

The invention belongs to the technical field of biology, and particularly relates to a phosphorylated oil tea meal peptide calcium chelate and application thereof in a calcium enhancer. Oil-tea meal is used as a raw material to extract protein, oil-tea meal active peptide is prepared through a biological enzymolysis method, oil-tea meal polypeptide AHW is screened out through bioinformatics analysis, and the calcium chelation rate of the oil-tea meal polypeptide AHW is 34.8% + / -1.65%. The chelating effect of phosphorylated oil-tea meal polypeptide P-AHW and Ca is further explored, and when the mass ratio of P-AHW to Ca is 1: 6, the chelating rate of the chelate P-AHW-Ca is increased to 61.67% + / -0.71%. The invention also verifies that the P-AHW-Ca chelate has good stability under the influence of different pH values, different temperatures and different food additives, and simulates gastric juice and intestinal juice to prove that the P-AHW-Ca chelate has good gastrointestinal tract adaptability. The invention is applied to preparation of calcium absorption promoting products, or preparation of calcium enhancer products, or preparation of calcium nutritional supplement products.

The invention discloses a micron-sized liquid calcium composition for promoting calcium absorption and a preparation method of the micron-sized liquid calcium composition, and belongs to the technical field of calcium supplements. The composition comprises the following raw materials: calcium citrate, milk mineral salt, calcium gluconate, casein peptide, hydrolyzed yolk peptide, L-lysine, vitamin D microcapsule powder, natto powder, xanthan gum, L-malic acid, xylitol, fructo-oligosaccharide, concentrated fruit juice, edible essence and water. The preparation method comprises the following steps: weighing, premixing, pretreating, preparing liquid, suspending, homogenizing and emulsifying, fixing volume, filling and sealing, and sterilizing. Practice verifies that the technology is advanced, the scheme is systematic, the benefit is remarkable, the industrial pain points that a traditional calcium agent is difficult to dissolve, poor in absorption and poor in taste are thoroughly solved, the economic and social benefits are huge, and great significance is achieved for promoting the high-quality development of the nutrition and health industry in China.

The application discloses a milk powder formula containing hydrolyzed whey protein and calcium-phosphorus matching and a preparation method, relates to the technical field of milk powder preparation, and contains core components such as whole milk powder, skim milk powder, hydrolyzed whey protein and compound adjuvants according to the percentage by weight, the molar ratio of calcium to phosphorus is 1.8-2.0:1, the milk solid content is greater than or equal to 70%, and the product meets the requirements of the national standard GB19644-2024, the preparation method comprises the following steps: raw material pretreatment, step-by-step dry powder mixing, optional dry granulation, drying and screening and the like, and the whole process is suitable for the dry production process of a factory. Through the cooperation of accurate formula design and fine dry process, the application improves the protein digestion and absorption rate and the calcium absorption and utilization rate, guarantees the stability of functional components, has strong product compliance and high practicability, can provide targeted nutritional support for the growth and development of children and adolescents, and has a wide application prospect.

The application discloses a system and method for capturing CO2 by indirect mineralization of desulfurization gypsum, and the system comprises a desulfurization gypsum leaching device for leaching Ca in desulfurization gypsum by an ammonium salt solution 2+ , obtaining a calcium-rich leaching solution; a calcium silicate generating device for generating calcium silicate by reacting the calcium-rich leaching solution with a silicate; a CO2 absorption device for absorbing CO2 by an alkali solution, generating a carbonate solution; and a calcium carbonate generating device for converting calcium silicate into calcium carbonate and regenerating the alkali solution by reacting the calcium silicate with the carbonate solution. The application can make the desulfurization gypsum be resourceized and utilized, and meanwhile, can mineralize and store CO2.

The invention discloses a glucosamine chondroitin capsule and a preparation method thereof, relates to the technical field of health-care food, and aims to improve the calcium absorption efficiency and protect articular cartilage through the synergistic effect of multiple components so as to realize preventive intervention and symptom improvement on osteoporosis. The capsule comprises the following components in parts by weight: 160-190 parts of calcium carbonate, 230-270 parts of glucosamine sulfate, 30-70 parts of chondroitin sulfate, 15-25 parts of casein phosphopeptides and 1-3 parts of magnesium stearate, preferably 175 parts of the components, 250 parts of the components, 50 parts of the components, 23 parts of the components and 2 parts of the components, and the dosage form is a hard capsule of which the total weight of each capsule is 0.5 g. The preparation method comprises the following steps: sieving the raw materials through a 60-mesh sieve, crushing the glucosamine sulfate, sieving, mixing twice, respectively controlling the rotating speeds of a mixer at 20-25r / min and 15-20r / min, filling into a No. 0 capsule shell, polishing, internally packaging, externally packaging and the like. According to the invention, multiple components synergistically supplement calcium and protect joints, step-by-step mixing and particle size control ensure quality, the raw materials are safe and compliant, and both effectiveness and safety are achieved.

The application provides a preparation method of Chlorella pyrenoidosa protein peptide-calcium chelate, and the preparation method comprises the following steps: S1, Chlorella pyrenoidosa protein is dissolved in deionized water, the pH is adjusted to 2-13, stirring is carried out for 1-5 hours, centrifugation is carried out, the supernatant is taken, and a Chlorella pyrenoidosa protein treatment solution is obtained; S2, calcium chloride is added to the Chlorella pyrenoidosa protein treatment solution, water bath chelation is carried out at 35-38 DEG C for 1.8-2.2 hours, centrifugation is carried out, anhydrous ethanol is added to the supernatant, standing is carried out, centrifugation is carried out again, the precipitate is collected, and freeze-drying is carried out, and the Chlorella pyrenoidosa protein peptide-calcium chelate is obtained. The preparation process is simple, no toxic side reagent is used, energy consumption is low, the prepared product is verified to have a calcium absorption promoting effect through animal experiments, and solid theoretical support is provided for the development and application of the Chlorella pyrenoidosa protein peptide-calcium chelate as a new bone health promoter.