Pharmaceutical preparation containing chitosan, drug transdermal patch and preparation method thereof

Abstract

The invention relates to the field of medicine, in particular to a pharmaceutical preparation, a drug transdermal patch containing the pharmaceutical preparation and a preparation method thereof. The pharmaceutical preparation includes encapsulated medicine and unencapsulated medicine, and the encapsulated medicine includes medicine A and an inclusion material encapsulating the medicine A, and the inclusion material contains chitosan and / or its derivatives ; the unencapsulated drug is drug B; the drug A is the same as or different from the drug B; The pharmaceutical preparation and the drug transdermal patch of the present invention can release effective dose of drug persistently (up to 7 days) and stably, and have strong controllability to meet the drug needs of patients of different degrees.

Description

technical field

[0001] The invention relates to the field of medicine, in particular to a pharmaceutical preparation, a drug transdermal patch containing the pharmaceutical preparation and a preparation method thereof. Background technique

[0002] External treatment is a commonly used method in clinical practice. In the early days, it was mostly in the form of Chinese herbal plasters, which were used to apply acupoints or local injuries to achieve therapeutic effects. This treatment method is simple and easy to operate, and has a high degree of patient acceptance.

[0003] In addition, for Western medicines that are traditionally taken orally or injected, transdermal patches have appeared in recent years to replace oral or injected. On the other hand, it can increase patient acceptance. However, it is still difficult for the drug to release an effective dose through the stratum corneum of the skin, and the penetration dose, stability and duration have not been ideal. In t...

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