Color spot-removing and repairing composition containing tea polyphenol and stem cell active ingredients as well as preparation method and application of color spot-removing and repairing composition

A technology of active ingredients and compositions, applied in the field of cosmetics and external pharmaceuticals, can solve problems such as limited repairing effect, excessive harmful substances, poor freckle removal effect, etc., and achieve the effect of broad market prospects, wide application and wide applicability

Pending Publication Date: 2020-12-29
DALIAN INNOVATION INST OF STEM CELL & PRECISION MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, most freckle products on the market use excessive chemical raw materials, harmful substances exceed the standard, and the freckle effect is not good. Most of them do not have the e

Method used

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  • Color spot-removing and repairing composition containing tea polyphenol and stem cell active ingredients as well as preparation method and application of color spot-removing and repairing composition
  • Color spot-removing and repairing composition containing tea polyphenol and stem cell active ingredients as well as preparation method and application of color spot-removing and repairing composition
  • Color spot-removing and repairing composition containing tea polyphenol and stem cell active ingredients as well as preparation method and application of color spot-removing and repairing composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] A freckle-removing and repairing mask liquid containing tea polyphenols and stem cell active ingredients, which consists of the following components by weight:

[0048]

[0049] A freckle-removing and repairing facial mask liquid containing tea polyphenols and stem cell active ingredients is prepared by the following method:

[0050] 1) Extraction of exosome vesicles derived from stem cells: Human umbilical cord mesenchymal stem cells (BNCC100383) in good growth state were selected and cultured in human umbilical cord mesenchymal stem cell medium without fetal bovine serum. Collect the culture supernatant at 70%-80%. At 4°C, centrifuge at 300g for 10min to remove cells and collect the supernatant; centrifuge at 2000g for 10min to remove cell debris and collect the supernatant; then centrifuge at 10000g for 30min to collect the supernatant; ultracentrifuge at 140000g for 90min to collect the exosomes derived from stem cells Vesicles were stored at -80°C for future us...

Embodiment 2

[0058] Temperature stability experiment of freckle-removing and repairing facial mask liquid containing tea polyphenols and active ingredients of stem cells:

Embodiment 3

[0062] Centrifugation experiment of freckle-removing and repairing facial mask liquid containing tea polyphenols and active ingredients of stem cells:

[0063] Take 10ml of the facial mask solution in Example 3 and place it in a 15ml centrifuge tube, centrifuge it at 2000r / min for 30min, after taking it out, it will not separate, and will be uniform and stable. Restorative Mask Fluid is centrifugally stable.

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Abstract

The invention discloses a color spot-removing and repairing composition containing tea polyphenol and stem cell active ingredients as well as a preparation method and application of the color spot-removing and repairing composition, and belongs to the field of cosmetics and external medicines. The invention provides three color spot-removing and repairing composition formulas containing tea polyphenol and stem cell active ingredients and a preparation method thereof, wherein the three color spot-removing and repairing composition formulas are shown in three dosage forms of mask liquid, essencewater or spray and cream respectively, and the composition has the advantages of uniformity, stability, wide application and the like; according to the formula, the traditional Chinese medicine extract and the stem cell active factors which have antioxidant and repairing effects on skin color spots are selected as main functional components, so that the composition can be used for repairing the skin color spots and can also be used for daily skin care and the like.

Description

technical field [0001] The invention belongs to the field of cosmetics and external medicaments, and in particular relates to a freckle-removing and repairing composition containing tea polyphenols and stem cell active ingredients, a preparation method and application thereof. Background technique [0002] Spots are pigment spots, which refer to spots that are different in color from the surroundings. Including freckles, dark spots, chloasma and age spots, etc., which belong to pigmented disordered skin diseases. It is a common skin disease with brown or hyperpigmentation and disfigurement on the face due to the increase of skin melanin. It mainly occurs on the cheeks and forehead, and is aggravated after sun exposure. It is more common in women. One of the effective treatment methods currently used to treat pigmentation is the application of antioxidants, which gradually restore the darker oxidized pigments to a light or even colorless state. [0003] More and more studie...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61K8/49A61K8/99A61K8/67A61K8/9794A61Q19/02A61Q19/08A61Q19/00A61Q17/04A61Q17/00
CPCA61K8/9789A61K8/498A61K8/99A61K8/676A61K8/9794A61Q19/02A61Q19/08A61Q19/00A61Q17/04A61Q17/005A61K2800/522
Inventor 刘晶夏俊豪刘路宽
Owner DALIAN INNOVATION INST OF STEM CELL & PRECISION MEDICINE
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