Pharmaceutical composition with kidney protection effect

A composition and drug technology, applied in the field of pharmacy, can solve problems affecting the quality of life of patients, and achieve the effects of protecting the kidneys, lowering the dosage of drugs, and reducing the level of proteinuria
CN112438976AActive Publication Date: 2021-03-05SHENZHEN AUSA PHARM CO LTD +1
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SHENZHEN AUSA PHARM CO LTD
Publication Date
2021-03-05

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Abstract

The invention relates to a pharmaceutical composition with a kidney protection effect. The pharmaceutical composition consists of an endothelin inhibitor, enalapril, folic acid substances and a pharmaceutically acceptable carrier, wherein the endothelin inhibitor comprises atrasentan. The invention provides application of the pharmaceutical composition to preparation of medicines for preventing, treating or delaying chronic kidney diseases and diabetic nephropathy. Through the implementation of the application, the pharmaceutical composition is provided for patients, the curative effect can beimproved, the treatment compliance is increased, and the medical cost is reduced.
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Description

technical field

[0001] The invention relates to a pharmaceutical composition combined with an endothelin inhibitor, enalapril and folic acid substances and its application, belonging to the field of pharmacy. Background technique

[0002] Chronic kidney disease (CKD) is a chronic kidney structure and dysfunction caused by various reasons. It is estimated that about 500 million people in the world have different degrees of kidney disease. Therefore, CKD has become a global health problem. . The cost of medical services for CKD patients is 1.8 times that of people without chronic kidney disease, and the average cost of medical services for dialysis patients is 10.3 times that of people without chronic kidney disease. This brings a huge economic burden to patients and seriously affects their quality of life. In addition, the morbidity and mortality of cardiovascular diseases in CKD patients are significantly higher than those in the general population, and they appear early an...

Claims

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