Anti-inflammatory, anti-allergy and itching-relieving plant composition as well as preparation method and application thereof

A composition and antipruritic technology, applied in the directions of drug combinations, anti-inflammatory agents, antibacterial drugs, etc., can solve the problems of inability to fall asleep easily, slow onset of antipruritic effect, difficult to quickly relieve itching, etc. Effective time, prevent excessive accumulation of melanin, inhibit the effect of melanin synthesis

Pending Publication Date: 2021-04-09

上海加新生物科技有限公司

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AI-Extracted Technical Summary

Problems solved by technology

[0004] In view of the related technologies mentioned above, the inventor believes that although the natural plant ingredients have anti-allergic and anti-inflammatory effects, the antipruritic ef...

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Method used

Added hydrolyzed eggshell membrane, Angelica dahurica, Glabridin and nicotinamide in embodiment 8-10, compared with embodiment 1-7, the antipruritic effect and antipruritic effect of the plant composition prepared by embodiment 8-10 The onset time of itching is further improved, and after the plant composition prepared in Examples 8-10 is applied, the melanin content is reduced, which can effectively inhibit the synthesis and deposition of m...

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Abstract

The invention relates to the technical field of cosmetics and particularly discloses an anti-inflammatory, anti-allergy and itching-relieving plant composition and a preparation method thereof. The anti-inflammatory, anti-allergy and itching-relieving plant composition is prepared from the following components: herba portulacae, radix sophorae flavescentis, honeysuckle flower, folium artemisiae argyi, folium perillae, cacumen platycladi, herba salviae miltiorrhizae, fructus chaenomelis and cortex magnoliae officinalis. The preparation method comprises the following steps of: (1) crushing the radix sophorae flavescentis, the cacumen platycladi and the cortex magnoliae officinalis and extracting to obtain a first extracting solution; (2) extracting the herba portulacae, the honeysuckle flower, the folium artemisiae argyi, the folium perillae and the herba salviae miltiorrhizae by utilizing supercritical carbon dioxide to obtain a second extracting solution; (3) crushing the fructus chaenomelis and adding zymophyte to prepare fructus chaenomelis fermentation liquid; and (4) after uniformly mixing the first extracting solution, the second extracting solution and the fructus chaenomelis fermentation liquid, preparing the anti-inflammatory, anti-allergy and itching-relieving plant composition. The anti-inflammatory, anti-allergy and itching-relieving plant composition provided by the invention can be used for preparing cosmetics and has the advantages of rapid itching-relieving effect, good anti-inflammatory and anti-allergy effects, capability of preventing local melanin accumulation after allergy and non-uniform skin color.

Application Domain

Antibacterial agentsCosmetic preparations +10

Technology Topic

Anti-inflammatoryPlant composition +7

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Examples

Experimental program(13)
Comparison scheme(6)
Effect test(4)

Example Embodiment

[0037]Preparation of hydrolyzed eggshell membrane

[0038]Preparation Example 1: The 10kg egg shell is pulverized, and a 240 L concentration of water is added, then a 24 l concentration of 36% acetic acid is added, and the temperature is allowed to stand for 24 h at 45 ° C for 24 h, filtration, water washing, drying at 60 ° C for 1.5H. , Chopped, 10 l concentration of 20% sulfuric acid, heated to 80 ° C reflux extraction 5 h, add 3 kg of calcium carbonate, filtration, spray drying, pulverized to 1 um, and prepared a hydrolyzed shell film.

Example Embodiment

[0041]Example 1: An anti-inflammatory anti-sensitive antimoding plant composition, as shown in Table 1, the preparation method of the anti-inflammatory anti-itching plant composition, including the following steps:

[0042](1) Pull the bitter ginseng, side cypresses and thickness to 400 mesh, plus three times the total weight of the total weight, ultrasonic treatment, with a concentration of 60% ethanol, to obtain the first extract, the ultrasonic frequency is 25000 Hz The time is 30 min, the amount of ethanol is 3 times the total weight of the two, and the three times of the three, the thickness of the three, and the Tween 80 is added to ethanol, and the amount of Tween 80 is added 20% of ethanol.;

[0043](2) Crushing the horse teeth, honeysuckle, Ai Ye, purple, mouse, and papaya, extract with supercritical carbon dioxide, extracting pressure is 34 MPa, temperature is 40 ° C, carbon dioxide flow is 20 l / h, extract 10h, the second extract;

[0044](3) Crushing papaya, adding fermented bacteria, mixing uniform, adding 5 times weight deionized water, fermenting at 25 ° C, 0.2H of fermentation liquid at 95 ° C, adding papain to 2 times ethanol , Sealing extraction, produce papaya fermentation broth, fermented bacteria is a yeast, and the addition is 20% of papaya.

[0045](4) After mixing the first extract, the second extract, and papaya fermentation mixture, centrifugation, concentrated, and anti-inflammatory antipyr-sensitive antiplasmic plant compositions were obtained.

[0046]Table 1 Example 1-5 Substrate amount of anti-inflammatory anti-itch plant composition

[0047]

Example Embodiment

[0048]Example 6: An anti-inflammatory anti-itching plant composition, as shown in Table 1, the preparation method of the anti-inflammatory anti-itching plant composition, including the following steps:

[0049](1) Pull the bitter ginseng, side cypresses and mugs to 600 mesh, plus three of the total weight of 3.5 times the water, ultrasonic treatment, extraction with a concentration of 60% ethanol, resulting in the first extract, the ultrasonic frequency is 28000 Hz Time is 25 min, and the amount of ethanol is 3 times the total weight of the three, and the total weight of the three, the amount of Tween 80 is added to ethanol, and the addition of Tween 80 is 25% of ethanol.;

[0050](2) Crushing the horse teeth, honeysuckle, Ai Ye, purple, and papaya, extract with supercritical carbon dioxide, extracting pressure of 37 MPa, temperature is 38 ° C, carbon dioxide flow is 25 l / h, extraction 8h, the second extract;

[0051](3) Crushing papaya, adding fermented bacteria, mixing uniform, add 4 times weight deionized water, fermentation at 35 ° C, 0.5 times of a fermentation liquid at 100 ° C, adding papaya to ethanol , Sealing extraction, resulting papaya fermentation broth, fermented bacteria is a yeast, and the amount of adding amount is 25% of papaya;

[0052](4) After mixing the first extract, the second extract, and papaya fermentation mixture, centrifugation, concentrated, and anti-inflammatory antipyr-sensitive antiplasmic plant compositions were obtained.

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Description & Claims & Application Information

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Classification and recommendation of technical efficacy words

Soothes the skin
Suppress itching

Anti-inflammatory, anti-allergy and itching-relieving plant composition as well as preparation method and application thereof

AI-Extracted Technical Summary

Problems solved by technology

Method used

Abstract

Image

Examples

Example Embodiment

Example Embodiment

Example Embodiment

PUM

Description & Claims & Application Information

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