Rosa roxburghii active extract with anti-depression effect and application

Abstract

The invention relates to a rosa roxburghii active extract with an anti-depression effect and application. The active extract is obtained from rosa roxburghii fruits or rosa roxburghii fruit residues by adopting a chemical extraction or membrane separation technology, wherein the chemical extraction technology comprises the following steps of: performing alcohol reflux extraction on freshly squeezed rosa roxburghii fruit residues or rosa roxburghii fruits, filtering, concentrating to remove ethanol, adding water to disperse water-insoluble precipitates, filtering, washing the precipitates by using water and petroleum ether or n-hexane in sequence, removing water-soluble substances and grease, and drying, thereby obtaining the active extract. The active extract contains triterpene and flavone components, and the research finds that the active extract is obvious in anti-depression activity, can be used for preparing anti-depression medicines and auxiliary medicines or serving as a healthy food additive and has high application values and market prospects. The active extract disclosed by the invention has significance for high-value utilization and sustainable development of the rosa roxburghii industry, an intermediate or additive raw material is provided for the anti-depression medicines or health foods, and the preparation method is simple and feasible, low in cost and capable of realizing industrial production.

Description

technical field [0001] The invention relates to an extract of roxburghii fruit or pomace, in particular to an active extract of roxburghii with antidepressant properties and its application. Background technique [0002] Depression is a mental disorder, clinically manifested as chronic, recurrent attacks, and the main symptoms are negative manifestations such as depressed mood, loss of appetite, and mood dysfunction. Depression also has the characteristics of high morbidity, high disability rate, and high suicide rate, which seriously affects the physical and mental health and quality of life of patients, and can even be life-threatening. Studies have reported that depression has become the second largest mental illness in my country, and about one-fifth of the people in the country suffer from depression to varying degrees. The main manifestations of depression patients are: heavy mood, loss of basic interest in work and life, mental fatigue, and always feeling powerless t...

AI Technical Summary

Problems solved by technology

At present, the pharmacological effects of Rosa roxburghii mainly include the following aspects: anti-oxidation, anti-aging, regulating immune function, anti-tumor, lowering blood sugar, detoxification and sedation, hangover and liver protection, treatment of oral ulcer, treatment of gastric ulcer and promotion of digestion, anti-inflammatory Atherosclerosis, anti-renal fibrosis and radiation protection, etc., but there is no research on the antidepressant activity of Rosa roxburghii

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