MEDA biological chip copyright protection method based on logic encryption

Abstract

The invention relates to an MEDA biological chip copyright protection method based on logic encryption. The method comprises the steps: S1, acquiring mixed separation operation used in a biochemical protocol operated by an MEDA biological chip; s2, calculating an influence factor of each mixing separation operation; s3, for each hybrid separation operation, if the influence factor of the hybrid separation operation is greater than or equal to a threshold value, replacing the hybrid separation operation with a logic encryption module, and allocating a gold input key to the logic encryption module; s4, combining the gold input secret keys of the logic encryption modules in sequence to serve as gold activation secret keys required by activation of the MEDA biochip; s5, constructing a key coupling enhancement module according to the length of the gold activation key; s6, taking an output result of the gold activation key passing through the key coupling enhancement module as a gold decryption key of the logic encryption module; and S7, performing security evaluation on the currently constructed logic encryption system. According to the method, the safety of the MEDA biochip in the production process is improved, and a biochemical protocol of the MEDA biochip is protected from being stolen by an attacker.

Description

technical field [0001] The invention belongs to the field of biochip security, and in particular relates to a method for protecting copyrights of MEDA biochips based on logic encryption. Background technique [0002] Digital microfluidic biochips (DMFBs) are an emerging platform that has revolutionized the procedures for preparing biochemical reagents in biochemical laboratories. Compared with the preparation of biochemical reagents in traditional biochemical laboratories, digital microfluidic biochips have the advantages of high automation, low reagent consumption, large-scale production and fast analysis speed. [0003] Thanks to recent industry advances in materials, applications, and design automation, digital microfluidic biochips have transitioned to a commercially exploitable market in the past few years. Illumina in the United States has launched a product called NeoPrep NGS Library Prep based on a digital microfluidic biochip platform. The U.S. Department of Agric...

AI Technical Summary

Problems solved by technology

Since the horizontal supply chain production model requires the holder of the intellectual property to send the intellectual property to a third-party foundry, the intellectual property is vulnerable to intellectual property piracy or excessive manufacturing attacks

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