A vibrio parahaemolyticus lyase, its coding gene and its application

A technology of Vibrio hemolyticus and encoding gene, applied in the directions of lyase, application, genetic engineering, etc., can solve problems such as reducing effectiveness, and achieve the effects of high specificity, wide host spectrum, and high lysis efficiency
CN112813058BActive Publication Date: 2022-03-08湖北小胡鸭酱卤食品研究院有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
湖北小胡鸭酱卤食品研究院有限公司
Publication Date
2022-03-08

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Abstract

The invention relates to a Vibrio parahaemolyticus lyase, the amino acid sequence of which is shown in SEQ ID NO:1. The present invention also relates to a Vibrio parahaemolyticus lyase encoding gene, which encodes a protein having the sequence shown in SEQ ID NO:1. The present invention also provides the application of the above Vibrio parahaemolyticus lyase in lysing Vibrio parahaemolyticus. The vibrio parahaemolyticus lyase can lyse the vibrio parahaemolyticus, has high specificity for the vibrio parahaemolyticus, high lysis efficiency, and the host spectrum of the vibrio parahaemolyticus is wide.
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Description

technical field

[0001] The invention relates to the field of biotechnology, in particular to a Vibrio parahaemolyticus lyase, its coding gene and its application in lysing Vibrio parahaemolyticus. Background technique

[0002] Vibrio parahaemolyticus (V.parahaemolyticus) is a halophilic Gram-negative bacterium, which is an important food-borne pathogen worldwide, mainly distributed in the marine environment. Consumption of seafood contaminated by Vibrio parahaemolyticus can cause gastrointestinal disturbances resulting in symptoms of diarrhea, nausea and, in severe cases, death. Vibrio parahaemolyticus has become a biohazard in aquaculture, and humans use antibiotics to prevent contamination. Antibiotics work again as antibiotic use leads to the rapid spread of multi-antibiotic resistance in bacteria. With the emergence of extensively drug-resistant bacterial pathogens, phage therapy and other alternative or additional treatment modalities have received renewed attention. ...

Claims

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