Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Preparation method of 3D electrode for non-enzymatic blood glucose detection

A blood sugar detection and electrode technology, applied in the field of non-enzymatic glucose sensors, can solve the problems of narrow linear range and low sensitivity, and achieve the effect of solving low sensitivity and improving performance

Active Publication Date: 2021-06-01
NORTHEASTERN UNIV
View PDF7 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

When the obtained material is applied in the field of non-enzymatic glucose sensor, it exhibits excellent performance, solving the problem of traditional Cu 2 Low sensitivity and narrow linear range of O-based non-enzymatic glucose sensor

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation method of 3D electrode for non-enzymatic blood glucose detection
  • Preparation method of 3D electrode for non-enzymatic blood glucose detection
  • Preparation method of 3D electrode for non-enzymatic blood glucose detection

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] A 3D Cu / Cu for Non-enzymatic Blood Glucose Detection 2 The preparation method of O / NiO electrode comprises the steps:

[0030] (1) Configure the reaction solution

[0031] First weigh 0.5 millimoles of copper sulfate, and then weigh the ingredients according to the molar ratio, copper sulfate: sodium dodecylbenzenesulfonate: sodium hydroxide: sodium ascorbate = 1: 4.5: 90-110: 15-25, Add copper sulfate and sodium dodecylbenzene sulfonate together to a beaker containing 50ml of deionized water, add sodium hydroxide and sodium ascorbate to a beaker containing 50ml of deionized water respectively, and stir thoroughly to obtain a uniform solution;

[0032] (2) Preparation of Cu 2 O-packed octahedra

[0033] Add the mixed solution of copper nitrate and sodium dodecylbenzene sulfonate into 5 25ml beakers according to 10, 9, 9, 9, 9ml respectively, and mark them as A-E respectively; take 0.2ml of sodium ascorbate solution and add it dropwise Put into beaker A, after shaki...

Embodiment 2

[0039] A 3D Cu / Cu for Non-enzymatic Blood Glucose Detection 2 The preparation method of O / NiO electrode comprises the steps:

[0040] (1) Configure the reaction solution

[0041] First weigh 0.5 millimoles of copper sulfate, then weigh the ingredients in molar ratio, copper sulfate: sodium dodecylbenzenesulfonate: sodium hydroxide: sodium ascorbate = 1:5:100:20, and mix copper sulfate and Sodium dodecylbenzenesulfonate was added to a beaker containing 50ml of deionized water, sodium hydroxide and sodium ascorbate were respectively added to a beaker containing 50ml of deionized water, and fully stirred to obtain a uniform solution;

[0042] (2) Preparation of Cu 2 O-packed octahedra

[0043] Add the mixed solution of copper nitrate and sodium dodecylbenzene sulfonate into 5 25ml beakers according to 10, 9, 9, 9, 9ml respectively, and mark them as A-E respectively; take 0.25ml of sodium ascorbate solution and add dropwise Put into beaker A, after shaking for 10s, add 0.5ml o...

Embodiment 3

[0050] A 3D Cu / Cu for Non-enzymatic Blood Glucose Detection 2 The preparation method of O / NiO electrode comprises the steps:

[0051] (1) Configure the reaction solution

[0052] First weigh 0.5 millimoles of copper sulfate, then weigh the ingredients in molar ratio, copper sulfate: sodium dodecylbenzenesulfonate: sodium hydroxide: sodium ascorbate = 1: 5.5: 110: 25, and mix copper sulfate and Sodium dodecylbenzenesulfonate was added to a beaker containing 50ml of deionized water, sodium hydroxide and sodium ascorbate were respectively added to a beaker containing 50ml of deionized water, and fully stirred to obtain a uniform solution;

[0053] (2) Preparation of Cu 2 O-packed octahedra

[0054] Add the mixed solution of copper nitrate and sodium dodecylbenzene sulfonate into five 25ml beakers according to 10, 9, 9, 9, 9ml respectively, and mark them as A-E respectively; take 0.3ml of sodium ascorbate solution and add it dropwise Put into beaker A, after shaking for 10s, a...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to the technical field of non-enzymatic glucose sensors, in particular to a preparation method of a 3D electrode for non-enzymatic blood glucose detection. According to the method, a Cu2O stacked octahedron is prepared by using a seed mediation method, then NiO quantum dots are deposited on the surface of the obtained Cu2O stacked octahedron by using an electrochemical deposition technology, and a Cu layer appears between contact surfaces of a sensing material and a signal receiving electrode due to partial reduction of Cu2O occurring in the deposition process, so that the 3D Cu / Cu2O / NiO mixed electrode is obtained. When the obtained material is applied to the field of non-enzymatic glucose sensors, excellent performance is shown, and the problems that a traditional Cu2O-based non-enzymatic glucose sensor is low in sensitivity and narrow in linear range are solved.

Description

technical field [0001] The invention relates to the technical field of non-enzymatic glucose sensors, in particular to a method for preparing a 3D electrode for non-enzymatic blood sugar detection. Background technique [0002] Diabetes often leads to a range of life-threatening complications such as blindness, high blood pressure, kidney failure, and more. The onset of diabetes is usually associated with high glucose levels in a person's blood. Therefore, it is necessary to study a glucose sensor that can be used to measure blood glucose levels in real time. Currently commonly used glucose sensors are mainly divided into two categories: one is an enzyme sensor based on biologically active proteins such as glucose oxidase; the other is mainly a non-enzymatic glucose sensor based on gold, platinum and other precious metals. The former, as a typical biologically active molecule, can easily lose its activity under unfavorable conditions of temperature, humidity and pH, which ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): G01N27/30G01N27/327
CPCG01N27/308G01N27/327
Inventor 祁阳刘文彬
Owner NORTHEASTERN UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com