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Composition of rhodomyrtus tomentosa extract and surface active substance

A technology of surface active substances and compositions, which is applied in the field of extraction and application of natural extracts, and can solve problems such as solubility limitations

Pending Publication Date: 2021-06-11
妙弋(广州)贸易有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] Myrtle (Rhodomyrtus tomentosa) root, stem, and leaf extracts, especially leaf extracts, have high antibacterial and anti-inflammatory activities, but the use of these extracts is limited by their solubility

Method used

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  • Composition of rhodomyrtus tomentosa extract and surface active substance

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Example 1: Preparation of a myrtle essential oil dissolved in polyoxyethylene (20) sorbitan monooleate: 10 g of myrtle (Myrtaceae Myrtle) was distilled by steam The essential oil obtained from fresh leaves is mixed with 90g of polyoxyethylene (20) sorbitan monooleate, stirred and dissolved in a conventional stirring manner to form a transparent and uniform solution state, and obtained by dissolving in polyoxyethylene (20) sorbitan monooleate Myrtle essential oil dissolved in monooleate. The myrtle essential oil content of the composition is 10%, has good water solubility (water dispersibility), can be used for beauty and skin care products, scalp care products, oral care products, and has antibacterial, anti-inflammatory, whitening and lightening effects effect. Used as a chewing gum additive, it can reduce tongue coating, thereby reducing bad breath. It can also be used as a food additive and has antiseptic effect.

Embodiment 2

[0037] Example 2: Preparation of myrtleone (mixed) dissolved in polyoxyethylene (20) sorbitan monooleate: 100.0 grams of ethanol extract of myrtle leaves (total phenols 26.2%) Purified by one-step molecular distillation to obtain 31.7 grams of mixed myrtleone (72.1% based on total phenols) with higher purity, take 10 grams of myrtle extract with a total phenol content of 72.1% and 90 grams of polyoxyethylene ( 20) Mix sorbitan monooleate, stir and dissolve into a transparent and uniform solution state with conventional stirring, and obtain myrtone completely dissolved in polyoxyethylene (20) sorbitan monooleate (mix). The composition has a myrtle extract content of 10% and a total phenolic content of approximately 7.2%. The composition has good water solubility (water dispersibility), can be used in beauty and skin care products, scalp care products, and oral care products, and has very antibacterial effect. Used as a chewing gum additive, it can reduce tongue coating, there...

Embodiment 3

[0038] Example 3: Determination of the inhibitory effect of polyoxyethylene (20) sorbitan monooleate-myrtonone (mixed) composition with a total phenol content of 7.2% on melanocytes, tyrosinase and melanin Composite Effects:

[0039] In DMEM medium containing 8% FCS, 10 4 / 3ml, 3ml / well (6-well plate), culture B16 melanoma cells in vitro, add 0 μg / ml, 10μg / ml, 50μg / ml, 200μg / ml respectively (based on total phenol content, each group has 4 replicate wells ) The above-mentioned polyoxyethylene (20) sorbitan monooleate-myrtonone (mixed) preparation with a total phenol content of 7.2%, at 37 ° C, 5% CO 2 After culturing for 72 hours under the same conditions, the growth number of B16 melanoma cells and the content of melanin in the cells were measured respectively.

[0040] Determination of the growth of melanoma cells: add 5 mg / ml S tetramethylazolazolium blue (MTT) 10 μl / ml to the sample to be tested, discard the supernatant after continuing to cultivate for 72 hours, add 2 ml...

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Abstract

The invention discloses a composition of a rhodomyrtus tomentosa extract and a surface active substance, and relates to the field of extraction and application of natural extracts. The invention discloses a stable and uniform composition formed by mixing and dissolving the rhodomyrtus tomentosa extract, a rhodomyrtus tomentosa extract purified product and a surface active substance, and an application of the stable and uniform composition in the daily chemical fields of whitening, bacteriostasis and the like and the field of food additives. The composition has very excellent formula usability, and shows excellent dual effects of inhibiting melanin and inhibiting bacteria at the same time. The composition also has the detergency brought by the surfactant.

Description

technical field [0001] The invention relates to the field of extraction and application of natural extracts, in particular to a preparation method and application of a water-soluble or dispersible composition of myrtle (Rhodomyrtus tomentosa) extract and surfactant. Background technique [0002] Myrtle (Rhodomyrtus tomentosa) is a plant of the genus Myrtle in the family Myrtaceae, also known as twister, mountain twister, hill twister, etc. It is mainly distributed in the south and southeast of China, especially in the Lingnan area, and is an indicator plant for acidic soil. . Myrtle (Rhodomyrtus tomentosa) is a traditional folk medicinal plant in my country. The roots, stems, leaves, and fruits can be used as medicine or edible. Deficiency cough, stems and leaves can cure toothache, and tender tips are mainly used to treat carbuncles, toxins and tuberculosis. Its flowers are rose-red, the fruit is delicious, and can be used for wine making, and the nuts can be used for oil ...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61K8/92A61K8/86A61Q11/00A61Q19/02A61Q19/00A61Q5/02A61Q17/00A61Q5/00A61K36/61A61K47/46A61K47/14A61K47/22A61P1/02A23L3/3472A23L33/105A23L21/10A23G4/06A23G3/48
CPCA23G3/48A23G4/068A23L3/3472A23V2002/00A61K8/375A61K8/86A61K8/922A61K36/61A61K47/14A61K47/22A61K47/46A61K2800/49A61K2800/782A61Q5/006A61Q5/008A61Q5/02A61Q11/00A61Q17/005A61Q19/00A61Q19/02A23L21/10A23L33/105A61K8/9789A61P1/02A23V2200/10A23V2200/312A23V2200/30A23V2250/21
Inventor 弗里德里希莱赫曼其他发明人请求不公开姓名
Owner 妙弋(广州)贸易有限公司
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