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A kind of calcium iron zinc solid preparation and preparation method thereof

A solid preparation, calcium-iron-zinc technology, applied in the field of pharmaceutical preparations, can solve the problems of severe gastrointestinal reactions, gastrointestinal function degradation, preparation incompatibility, etc., to achieve the protection of iron smell, promote absorption, and improve solubility Effect

Active Publication Date: 2022-08-09
海而思(郑州)科技有限公司
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  • Abstract
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  • Claims
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AI Technical Summary

Problems solved by technology

[0005] Most calcium, iron and zinc products on the market have a single process and have not been processed, and the iron supplements used are all compounds with an iron smell and severe gastrointestinal reactions. Toddler, difficult to accept
However, the gastrointestinal function of the elderly is further degraded due to the degeneration of the body, and they are not suitable for preparations with strong gastrointestinal reactions.

Method used

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  • A kind of calcium iron zinc solid preparation and preparation method thereof

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Effect test

Embodiment 1

[0037] In parts by weight, the formula of the present embodiment calcium iron zinc particles is:

[0038] 45 parts of maltodextrin (DE value 20), 15 parts of beta-cyclodextrin, 17 parts of sweet orange powder, 0.12 parts of ferrous glycinate, 0.065 parts of zinc glycinate, 10 parts of calcium aspartate, 8 parts of xylitol, 3.6 parts of white sugar, 0.215 parts of steviol glycosides, 1 part of vitamin C, 1 part of citric acid.

[0039] Preparation:

[0040] Mixing and grinding cyclodextrin with ferrous glycinate, zinc glycinate and calcium aspartate to obtain cyclodextrin calcium iron zinc inclusion complex;

[0041] After mixing cyclodextrin calcium iron zinc inclusion complex, maltodextrin, fruit powder, xylitol, white sugar, stevioside, vitamin C and citric acid, spray an appropriate amount of binder (4 parts of 50% alcohol), After boiling, drying for 1 hour, drying at 60° C. for 90 minutes, until the moisture content is below 2%, and discharging to obtain granules.

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Abstract

The invention relates to the technical field of pharmaceutical preparations, in particular to a calcium iron zinc solid preparation and a preparation method thereof. In parts by weight, the raw and auxiliary materials of the calcium iron zinc solid preparation include: 1-50 parts of maltodextrin, 1-30 parts of cyclodextrin, 1-35 parts of fruit powder, 0.05-10 parts of iron source, and 0.001-8 parts of zinc source , 1-30 parts of calcium source, 1-30 parts of xylitol, 1-20 parts of white sugar, 0.01-4.0 parts of stevioside, 0.1-2 parts of vitamin C, 0.1-5 parts of citric acid; iron source is glycine iron and / or iron aspartate; zinc source is zinc glycinate and / or zinc aspartate; calcium source is calcium aspartate and / or calcium glycinate. The calcium iron zinc solid preparation of the invention has better bioavailability and good palatability.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to a calcium iron zinc solid preparation and a preparation method thereof. Background technique [0002] Calcium, iron, and zinc are important constituent elements of the human body, with special nutritional value and special physiological functions. Calcium-iron-zinc deficiency is a series of diseases caused by calcium-iron-zinc deficiency, especially in special populations such as the elderly, infants and pregnant women. It has become a serious social health problem all over the world. Calcium deficiency is mainly manifested in children with stunted growth, abnormal cartilage structure, poor bone calcification and rickets (multiple bone deformation, dysplasia of teeth, etc.). Calcium deficiency in pregnant women can cause fetal growth retardation and affect postnatal growth, causing children to be prone to convulsions, X-shaped legs, and O-shaped legs, as wel...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23L2/39A23L33/165A23L29/30A23L19/00A23L2/52A23L2/42A23L3/3562A23P10/30
CPCA23L2/39A23L33/165A23L29/35A23L19/09A23L2/52A23L2/42A23L3/3562A23P10/30A23V2002/00A23V2200/30A23V2250/032A23V2250/1578A23V2250/1592A23V2250/1642A23V2250/262A23V2250/5114A23V2250/5112A23V2250/6422A23V2250/708A23V2250/082
Inventor 秦和平张风洁刘宁
Owner 海而思(郑州)科技有限公司
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