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Social identification and evaluation system based on social conditioned reflex and application of social identification and evaluation system

A technology for evaluating systems and social objects, applied in the field of social recognition evaluation systems, which can solve problems such as stimulation and inability to detect specific identity information of social objects

Pending Publication Date: 2021-09-10
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] (2) The three-box social experiment can only detect whether the tested mice are familiar with the social object, but cannot detect the specific identity information of the social object
No reports of using social objects as conditioned stimuli

Method used

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  • Social identification and evaluation system based on social conditioned reflex and application of social identification and evaluation system
  • Social identification and evaluation system based on social conditioned reflex and application of social identification and evaluation system
  • Social identification and evaluation system based on social conditioned reflex and application of social identification and evaluation system

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Embodiment 1 Social Recognition Evaluation System Based on Social Conditioning

[0041] The invention provides a social recognition evaluation system based on social conditioning for test animals. The test animals can be rats or mice. The social recognition evaluation system is used to evaluate and detect the social response of the test animal to the social object animal, such as its reaction behavior, and to train the test animal based on social conditioning.

[0042] figure 1 It is a three-dimensional schematic diagram of an exemplary social recognition evaluation system based on social conditioning of the present invention. figure 2 is a schematic side view cross-sectional view of an exemplary social recognition evaluation system based on social conditioning of the present invention. image 3 is a schematic top view of another exemplary social recognition evaluation system based on social conditioning of the present invention.

[0043] like figure 1 , figure ...

Embodiment 2

[0059] Example 2 Social Recognition Response Behavior Detection and Training

[0060] The social recognition evaluation system based on social conditioning described in Example 1 was used to detect and train the social recognition response behavior of the mice.

[0061] The test mice were fixed on the fixtures in the fixed cabin, and multiple social object mice were respectively placed on the fixtures in each cabin of the rotating cabin. The head fixing part is connected with the fixing sheet installed on the head of the mouse to fix the head of the mouse. Make the head of the subject mouse face the head of the social object mouse. The distance between the nose of the test mouse and the edge of the open end of the fixed cabin, and the distance between the nose of the social object mouse and the edge of the rotating cabin is about 25 mm.

[0062] Set the position of the rotating cabin where different social objects are located in the host computer, and the valence of the coup...

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Abstract

The invention provides a social identification and evaluation system based on social conditioned reflex for a tested animal. The system comprises a fixed cabin and a rotating cabin, wherein the rotating cabin comprises two or more separated cabin chambers and can rotate to a position where any one of the two or more separated cabin chambers is independently connected with the fixed cabin, so that the tested animal in the fixed cabin receives the information of the social object animal in the cabin chamber of the rotating cabin, and the information comprises one or more of visual information, olfactory information or auditory information. The invention also provides a method for evaluating and detecting the social reaction of the tested animal and training the social conditioned reflex of the tested animal by coupling unconditioned stimulus of the tested animal and different social individuals through the social identification and evaluation system.

Description

technical field [0001] The present invention relates to the field of biological methods and devices. In particular, the present invention relates to a social recognition assessment system for the study of animal behavior and its use. Background technique [0002] Social recognition refers to the ability to recognize different social individuals and is a basic component of social behavior. Therefore, how to detect social recognition is an important issue in the fields of animal behavior and social neurobiology. Mice are a classic model animal, and the traditional paradigm for testing social recognition ability is the three-box social experiment. In the experiment, familiar mice and unfamiliar mice were placed on both sides of the three boxes. The social recognition ability of the tested mice was evaluated by the time difference between the tested mice approaching the familiar mice and the unfamiliar mice. However, the three-box social experiment has the following problems...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01K15/02A01K15/04
CPCA01K15/027A01K15/04
Inventor 倪哲一薛超予谭日升周安琪胡海岚
Owner ZHEJIANG UNIV
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