Quantification method of microvessel distribution symmetry in gastric mucosal staining and magnification imaging

Abstract

The invention discloses a microvessel distribution symmetry quantification method for gastric mucosa dyeing amplification imaging, which comprises an image segmentation method, a centroid eccentric distance method, a centroid eccentric angle method and a density method. The image segmentation method is used to extract the clear area and the whole picture of microvessels in the gastroscope image; the centroid eccentricity method quantifies the symmetry of the whole microvessel distribution from the angle of centroid eccentricity; the centroid eccentric angle method quantifies the symmetry of the whole microvessel distribution from the perspective of centroid eccentricity angle ; The density method quantifies the distribution symmetry of microvessels in the whole map from the perspective of density. Finally, by weighting the symmetry score of centroid eccentricity distribution, centroid eccentricity angle distribution symmetry score, and density distribution symmetry score, the final symmetry coefficient of microvessel distribution in the whole map is obtained, and then according to the symmetry coefficient of the distribution of microvessels in the whole map, the distribution The symmetry level is judged.

Description

technical field

[0001] The invention relates to the technical field of image processing in the medical field, in particular to a method for quantifying the symmetry of microvessel distribution in gastric mucosa staining and magnifying imaging. Background technique

[0002] Gastrointestinal tumors are one of the most common malignant tumors. In 2015, the number of patients with esophageal cancer, gastric cancer, and colorectal cancer in my country was nearly 1.5 million, and the death toll was more than 1 million, accounting for 1 / 3 of the total cancer deaths. The fundamental reason why malignant tumors endanger human health is that they cannot be detected early. Gastrointestinal endoscopy is the most commonly used powerful method for screening and diagnosing early-stage tumors of the digestive tract. The advent of chromoendoscopy established the endoscopic diagnosis method of early gastric cancer. The combined application of magnifying gastroscopy and electronic chromoend...

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