Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Traditional Chinese medicine composition for treating type II diabetes and application

A technology for diabetes and composition, applied in the field of traditional Chinese medicine composition, can solve the problem of inability to restore insulin sensitivity and the like, and achieve the effects of good curative effect, fast absorption and strong effect

Active Publication Date: 2021-10-22
北京精医和生医药科技有限公司
View PDF0 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the treatment of type II diabetes is only limited to the treatment of these symptoms, and cannot restore insulin sensitivity in insulin-sensitive tissues. Western medicines often use hypoglycemic drugs with different mechanisms according to the cause of the disease, but most of them have contraindications and adverse reactions, such as many Studies have reported some side effects related to conventional treatment: hypoglycemia caused by sulfonylureas and insulin injections, and hepatotoxicity after specific administration of thiazolidinedione drugs. Efforts to seek treatment and ideal methods and drugs for hypoglycemia are still the current world medical problems

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Traditional Chinese medicine composition for treating type II diabetes and application
  • Traditional Chinese medicine composition for treating type II diabetes and application
  • Traditional Chinese medicine composition for treating type II diabetes and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] Clinical research on the treatment of type 2 diabetes mellitus by Shenling Jiangtang decoction of embodiment 1

[0046] (1) Objects: Diabetic patients diagnosed at Dongzhimen Hospital of Beijing University of Traditional Chinese Medicine from April 2019 to April 2021 were retrospectively analyzed and divided into group A, group B, and group C. The patients in group A took XiaoXianxiong decoction, the patients in group B took Fangji Fuling and XiaoXianxiong formula, and the patients in group C took Shenling Jiangtang formula. A total of 121 patients were treated with Shenling Jiangtang Prescription and related formulations for more than 3 months, including 40 cases in the A prescription group, 38 cases in the B prescription group, and 43 cases in the C prescription group. There were no statistically significant differences in gender and age between the groups.

[0047] (2) Grouping and pharmacy: According to the sources of prescriptions, group A (Huanglian 15-40g, Pinel...

Embodiment 2

[0090] Example 2 Experiment of efficacy of water extract of Shenling Jiangtang Recipe in treating type II diabetic mice

[0091] The diabetes model fed with high-fat feed is a classic type II diabetes model, which has the characteristics of simplicity, easy film formation, long-term maintenance of high blood sugar, and stable disease. The main symptoms are abnormal glucose tolerance and metabolic disorder, which are related to the etiology and pathological process of human diabetes. Similarly, the high-fat diet-induced diabetes model can therefore be used as an experimental type II diabetes model. In this example, type II diabetes induced by high-fat feed was used as an experimental disease model to explore whether Shenling Jiangtang decoction could delay the progression of type II diabetes, and compared the efficacy maintenance of the two with Xiaoxianxiong decoction after drug withdrawal.

[0092] 1. Experimental materials

[0093] (1) Experimental animals

[0094] 40 clea...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a traditional Chinese medicine composition for treating type II diabetes and application. The traditional Chinese medicine composition comprises the following components: 10-25 parts of cocculus orbiculatus, 15-50 parts of cassia twig, 15-40 parts of coptis chinensis, 20-80 parts of poria cocos, 20-50 parts of radix glehniae and 20-50 parts of trichosanthes kirilowii maxim (kernel). The traditional Chinese medicine composition can be used for preparing a preparation for treating type II diabetes. The traditional Chinese medicine composition has a good curative effect on high fasting blood glucose, postprandial blood glucose rise, dyslipidemia and particularly insulin resistance caused by type 2 diabetes, and can remarkably improve clinical symptoms of type 2 diabetes patients; the composition has no obvious damage to the liver function, and has a protective effect, so that the safety is relatively high, and the compound has a wide application prospect in the field of treatment of type II diabetes mellitus.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition and application for treating type II diabetes. Background technique [0002] Diabetes is a metabolic disease characterized by chronic hyperglycemia. According to the International Diabetes Federation, as of February 2021, more than 425 million people worldwide suffer from diabetes. The latest survey data shows that the prevalence of diabetes in my country is 11.2%. Its high incidence and related chronic complications such as heart, brain, kidney, and foot are the main causes of disability or death caused by diabetes, which brings huge benefits to patients. The economic burden has become a worldwide public health problem that seriously threatens human health. Type II diabetes mellitus (T2DM) is still a global health problem. It is characterized by insulin resistance and often accompanied by progressive insufficient secretion o...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/718A61P3/10
CPCA61K36/59A61K36/54A61K36/718A61K36/076A61K36/23A61K36/428A61P3/10A61K2236/331A61K2300/00
Inventor 刘伟敬谢淑华蔡雨孜胡天宝娄文娇赵启菡
Owner 北京精医和生医药科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com