A kind of preparation method and application of the composition containing nmn

A composition and water-soluble polymer technology, which can be applied in the directions of medical preparations containing active ingredients, drug combinations, and non-active ingredients medical preparations, etc., can solve problems such as NMN decomposition, and achieve improved utilization and efficacy. , to maintain the efficacy of the drug
CN113559112BActive Publication Date: 2022-04-22SHANDONG RUNDE BIOTECH CO LTD

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SHANDONG RUNDE BIOTECH CO LTD
Publication Date
2022-04-22

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Abstract

The present invention relates to the technical field of NMN preparation, in particular to a preparation method and application of a NMN-containing composition. The method comprises: (1) mixing the NMN aqueous solution obtained after being prepared by microbial fermentation with an extractant, and standing for separation After layering, take off the oily liquid containing NMN of the layer, and set aside. (2) Mix the oily liquid with monoglycerides and phospholipids evenly, and then granulate to obtain lipid granules containing NMN, which are set aside. (3) adding the NMN-containing lipid particles into the enteric coating solution containing bone powder for coating, and drying after completion to obtain the NMN-containing composition. The method of the invention integrates the preparation stage of NMN and the preparation stage of capsules, effectively simplifies the preparation process of NMN capsules, and alleviates the problem that NMN is easily decomposed by external factors.
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Description

technical field

[0001] The invention relates to the technical field of NMN preparation, in particular to a preparation method and application of a composition containing NMN. Background technique

[0002] NMN, β-nicotinamide mononucleotide, is a naturally occurring biologically active nucleotide. NMN has two different forms, α and β, and the β isomer is the active form of NMN. NMN is widely distributed in daily food, such as vegetables, fruits, meat, etc. are rich in NMN, and the human body will continue to synthesize NMN. Modern scientific research shows that: NMN plays an important role in the energy generation of human cells. It participates in the synthesis of NAD (nicotinamide adenine dinucleotide, an important coenzyme for cell energy conversion) in cells. Nicotinamide mononucleotide W+NMN It can increase NAD in organs, thereby inhibiting the aging of nerves and blood vessels, and can also improve the symptoms of diabetes. However, with age, the body's ability to syn...

Claims

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