Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Application of pleuromutilin compound in resisting plant pathogenic bacteria

A phytopathogenic bacteria, pleuromutilin technology, applied in plant growth regulators, botanical equipment and methods, applications, etc., to achieve the effects of high bactericidal activity, reduced R&D costs and cycles, and broad bactericidal spectrum

Active Publication Date: 2022-02-08
LANZHOU UNIVERSITY
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no report about its anti-phytopathogenic bacteria activity, so it can be used as a lead to further develop new anti-phytopathogenic bacteria agents

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of pleuromutilin compound in resisting plant pathogenic bacteria
  • Application of pleuromutilin compound in resisting plant pathogenic bacteria
  • Application of pleuromutilin compound in resisting plant pathogenic bacteria

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Example 1: The compounds pleuromutilin and warnemulin hydrochloride are purchased from the market, pleuromutilin CAS: 125-65-5, purity >98%; warnemulin hydrochloride CAS: 133868-46-9, Purity >98%. Its structural formula is as follows:

[0013]

Embodiment 2

[0014] Embodiment 2: Determination of antibacterial activity of pleuromutilin compounds

[0015] The strains used in this experiment were those frozen in the laboratory at -80°C with 30% glycerol. Take out the frozen strains and place them on NB solid medium (beef extract: 3g, peptone: 5g, yeast powder: 1g, sucrose: 10g, agar: 15g, distilled water: 1L, pH7.0; sterilized at 121°C for 20min) Streak and incubate at 28°C until a single colony grows. Pick a single colony on the solid medium and put it into NB liquid medium (beef extract: 3g, peptone: 5g, yeast powder: 1g, sucrose: 10g, distilled water: 1L; 28°C, 180rpm shaking culture to the logarithmic growth phase. Dilute the strains in the logarithmic growth phase to about 10 with NB liquid medium 6 CFU / mL for use. The compounds were respectively dissolved in DMSO, added into the liquid medium, mixed evenly, and prepared into a drug-containing liquid medium with a concentration of 200 μg / mL. Take 50 μL drug-containing mediu...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention belongs to the field of medicinal chemistry, and discloses an application of a pleuromutilin compound in prevention and treatment of plant diseases caused by a rice bacterial leaf blight pathogenic bacterium Xanthomonas oryzae ACCC 11602, a citrus canker pathogenic bacterium Xanthomonas axonopodis pv.Citri and a potato black shank pathogenic bacterium Pectobacterium atrosepticaACCC 19901. The commercially available compounds such as pleuromutilin have the characteristics of broad spectrum, high efficiency and the like as plant pathogenic bacterium resisting agents, and have further research and development values.

Description

technical field [0001] The invention belongs to the field of natural medicinal chemistry, and discloses that pleuromutilin compounds are effective in preventing and treating bacterial blight of rice caused by Xanthomonas oryzae ACCC 11602, Xanthomonas axonopodispv.Citri and Pectobacterium atroseptica ACCC 19901. Use in agricultural bacterial diseases. Background technique [0002] Bacterial diseases are the most difficult diseases of crops to control, and cause huge losses to agriculture all over the world every year. There are about 500 kinds of bacterial crop diseases in the world, and there are nearly 70 kinds of major bacterial crop diseases in my country. Among them, bacteria of the genus Xanthomonas (Xanthomonas sp.), such as rice bacterial blight pathogen and citrus canker pathogen, are two plant pathogenic bacteria with strong vitality, high pathogenicity, and great economic losses. It is estimated that worldwide potato production is reduced by 25% each year due to...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A01N45/02A01P1/00
CPCA01N45/02
Inventor 刘映前丁艳艳贺颖慧马越安俊霞张智军赵文斌杨程杰王艺荣朱丽菹
Owner LANZHOU UNIVERSITY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com