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Skin whitening and brightening repair composition containing active polypeptide and application of skin whitening and brightening repair composition

An active peptide, whitening and brightening technology, applied in the direction of drug combination, allergic diseases, cosmetic preparations, etc., can solve the problems of single skin effect, slow effect, limited amount of peptide added, etc., to enhance the whitening effect and anti-wrinkle ability. , better skin improvement effect

Active Publication Date: 2022-08-09
ZHEJIANG PEPTITES BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are various cosmetics or skin care products on the market, but most skin care products only add a certain type of functional peptide as the active substance of skin care products, so the effect obtained by the skin is relatively simple, and the effect is slow; moreover, Most of the skin care products currently on the market that use peptides as active ingredients add peptides or peptide stock solutions directly to the base of conventional skin care products. Based on the consideration of the production and stability of the entire formula, the amount of peptides added will be limited.

Method used

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  • Skin whitening and brightening repair composition containing active polypeptide and application of skin whitening and brightening repair composition
  • Skin whitening and brightening repair composition containing active polypeptide and application of skin whitening and brightening repair composition
  • Skin whitening and brightening repair composition containing active polypeptide and application of skin whitening and brightening repair composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] A whitening and skin-brightening repair composition containing active polypeptides, comprising: active polypeptide complexes, and functional active substances (isoferulic acid amide derivatives);

[0043] Active polypeptide complex components, by weight percentage, including palmitoyl tetrapeptide-7 0.03 part, tripeptide-1-copper 0.2 part, palmitoyl tripeptide-1 0.01 part, palmitoyl tripeptide-5 0.005 part, palmitoyl tripeptide-5 0.005 part, Acyl pentapeptide-4 0.02 parts, acetyl hexapeptide-8 0.01 parts, snake venom 0.005 parts, melittin 0.025 parts, nonapeptide-1 0.003 parts, carnosine 0.05 parts, tetrapeptide-300.015 parts, trifluoroacetyl Tripeptide-2 0.007 copies, hexapeptide-2 0.02 copies.

[0044] Preparation of a liquid cosmetic:

[0045] The stock solution was added to the basic formula of the essence, and then adjusted with citric acid to pH=6.0 to obtain a liquid cosmetic (wherein, the stock solution accounted for 10wt%).

[0046] Among them, the formula of...

Embodiment 2

[0059] The preparation method of isoferulic acid amide derivatives used in this example is the same as that in Example 1.

[0060] A whitening and skin-brightening repair composition containing active polypeptides, comprising: active polypeptide complexes, and functional active substances (isoferulic acid amide derivatives);

[0061] Active polypeptide complex components, by weight percentage, including palmitoyl tetrapeptide-7 0.01 part, tripeptide-1-copper 0.1 part, palmitoyl tripeptide-1 0.05 part, palmitoyl tripeptide-5 0.03 part, palmitoyl tripeptide-5 0.03 part, Acylpentapeptide-4 0.02 part, acetyl hexapeptide-8 0.008 part, snake venom 0.04 part, melittin 0.005 part, nonapeptide-1 0.002 part, carnosine 0.005 part, tetrapeptide-300.07 part, trifluoroacetyl Tripeptide-2 0.02 parts, hexapeptide-2 0.05 parts.

[0062] Preparation of a liquid cosmetic:

[0063] The stock solution was added to the basic formula of the essence, and then the pH was adjusted to 5.2 with trietha...

Embodiment 3

[0073] The preparation method of isoferulic acid amide derivatives used in this example is the same as that in Example 1.

[0074] A whitening and skin-lightening repairing composition containing an active polypeptide is different from that of Example 1:

[0075] Active polypeptide complex components, by weight percentage, including palmitoyl tetrapeptide-7 0.05 part, tripeptide-1-copper 0.15 part, palmitoyl tripeptide-1 0.05 part, palmitoyl tripeptide-5 0.001 part, palmitoyl tripeptide-5 0.001 part, Acylpentapeptide-4 0.04 parts, acetyl hexapeptide-8 0.009 parts, snake venom 0.035 parts, melittin 0.006 parts, nonapeptide-1 0.012 parts, carnosine 0.028 parts, tetrapeptide-300.005 parts, trifluoroacetyl Tripeptide-2 0.014 copies, hexapeptide-2 0.045 copies.

[0076] The preparation of a liquid cosmetic is different from Example 1: the active polypeptide complex in the stock solution formulation is prepared in this example, and the content is 4.45wt%; the content of isoferulic ...

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PUM

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Abstract

The invention discloses a skin whitening, brightening and repairing composition containing active polypeptide and application of the skin whitening, brightening and repairing composition, and relates to the field of cosmetics. The skin whitening, brightening and repairing composition containing the active polypeptide comprises an active polypeptide compound and a functional active substance, the active polypeptide compound comprises but is not limited to antioxidant polypeptide, inflammatory factor release inhibiting polypeptide, collagen supplementing polypeptide and skin brightening polypeptide; the functional active substance comprises but is not limited to one or more of isoferulic acid and isoferulic acid amide derivatives; the isoferulic acid amide derivative at least comprises adenosine and an epoxy alkyl group. The composition provided by the invention has multiple skin repairing effects, and the skin improving effect is better; wherein the whitening effect is obviously enhanced, and the anti-wrinkle capability is obviously improved; and meanwhile, the antioxidant and anti-allergic repair capabilities are better.

Description

technical field [0001] The invention belongs to the field of cosmetics, and in particular relates to a skin-whitening, brightening and repairing composition containing active polypeptides and uses thereof. Background technique [0002] The skin is an important and largest organ covering the entire body surface. It is the protector of the internal organs and tissues of the human body. At the same time, it is also the effector of internal organs, spirit and surrounding environment. play a particularly important role. Active biological peptides also play a unique and important physiological role in the defense and care of natural skin aging, such as skin tissue cell proliferation, cell chemotaxis and migration, repair and regeneration, vascular formation and reconstruction, pigment formation and removal As well as protein synthesis and secretion, metabolism and regulation. [0003] Peptides, especially some small molecular peptides, can essentially improve some skin problems ...

Claims

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Application Information

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IPC IPC(8): A61K8/65A61K8/64A61K8/49A61K8/37A61Q19/02A61Q19/08A61Q19/00A61P37/08
CPCA61K8/65A61K8/64A61K8/49A61K8/37A61K8/4946A61Q19/02A61Q19/08A61Q19/00A61P37/08A61K2800/592A61K2800/782Y02P20/55
Inventor 钱令页邢海英刘志国虞新友
Owner ZHEJIANG PEPTITES BIOTECH CO LTD
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