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Medicinal ointment containing zinc conjugated linoleate and sodium humate

A technology of conjugated linoleic acid and sodium humate, applied in medical preparations containing active ingredients, ointment delivery, antineoplastic drugs, etc.

Inactive Publication Date: 2004-07-07
XINJIANG TECHN INST OF PHYSICS & CHEM CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] In many existing technologies, there is no report of medicinal ointment containing conjugated linoleic acid zinc salt and sodium humate at home and abroad.

Method used

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  • Medicinal ointment containing zinc conjugated linoleate and sodium humate

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] First weigh the components according to the mass ratio: cis-9, trans-11-conjugated linoleic acid zinc salt: sodium brown humic acid and sodium black humic acid mixture: medical white oil: distilled water: Span: tert-butyl para Hydroquinone, the ratio of which is 30.15:31.6:28.14:10:0.1:0.01;

[0027] Heat 28.14 parts of medical white oil to 50°C, add 30.15 parts of cis-9, trans-11-conjugated linoleic acid zinc salt and 0.01 part of antioxidant tert-butylhydroquinone under stirring conditions to obtain liquid A;

[0028] Add 31.6 parts of the mixture of sodium brown humate and sodium black humate into 10 parts of distilled water, stir to dissolve, and heat to 70°C to obtain liquid B;

[0029] Then add liquid B and 0.1 part of surfactant Span to liquid A, emulsify with a powerful emulsifier for 0.5 hour, and cool to room temperature to obtain a medicinal ointment containing zinc conjugated linoleic acid and sodium humate .

Embodiment 2

[0031] First, each component is weighed according to the mass ratio: trans-9, cis-11-conjugated linoleic acid zinc salt and trans-10, a mixture of cis-12-conjugated linoleic acid zinc salt: sodium palmate: Medical white oil: distilled water: sucrose polyester: tert-butyl p-hydroxyanisole, the ratio is 30:40:24.77:5:0.2:0.03;

[0032] Heat 24.77 parts of medical white oil to 70°C, add trans-9, cis-11-conjugated linoleic acid zinc salt and trans-10, 15 parts of cis-12-conjugated linoleic acid zinc salt and Antioxidant tert-butyl p-hydroxyanisole 0.03 part obtains A liquid;

[0033] Add 40 parts of sodium brown humate to 5 parts of distilled water, stir to dissolve, and heat to 60°C to obtain liquid B;

[0034] Then add liquid B and 0.2 parts of surfactant sucrose polyester to liquid A, emulsify with a strong emulsifier for 3 hours, and cool to room temperature to obtain a drug containing zinc conjugated linoleic acid and sodium humate. Use ointment.

Embodiment 3

[0036] First weigh each component according to the mass ratio: trans-10, cis-12-conjugated linoleic acid zinc salt and cis-9, trans-11-conjugated linoleic acid zinc salt mixture: sodium fulvic acid: medical White oil: distilled water: glyceryl monostearate: butylated hydroxytoluene, the ratio is 35:25:20:19.18:0.8:0.02;

[0037]Heat 20 parts of medical white oil to 60°C, add trans-10, cis-12-conjugated linoleic acid zinc salt and cis-9, trans-11-conjugated linoleic acid zinc salt each 17.5 parts and anti- The oxidizing agent butylated 0.02 part of hydroxytoluene to obtain liquid A;

[0038] Add 25 parts of sodium fulvic acid into 19.18 parts of distilled water, stir to dissolve, and heat to 50°C to obtain liquid B;

[0039] Then add liquid B and 0.8 parts of surfactant glyceryl monostearate to liquid A, emulsify with a strong emulsifier for 2 hours, and cool to room temperature to obtain a compound containing zinc conjugated linoleic acid and humic acid Sodium medicinal oint...

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Abstract

A medical ointment for suppressing fungus and bacteria and treating skin cancer, eczema, psoriasis and dermatitis is prepared from zinc conjugated linoleate, sodium humate, medical vaseline, distilled water, surfactant and antioxidant through heating medical vaseline, adding zinc conjugated linoleate and antioxidant to obtain mixture, dissolving sodium humate in distilled water, adding the solution to said mixture, adding surfactant, emulsifying and cooling. It has unique curative effect.

Description

technical field [0001] The invention relates to a medical external ointment, in particular to a medicinal ointment containing zinc conjugated linoleic acid and sodium humate. Background technique [0002] Conjugated Linoleic Acid (CLA) is a mixture of a series of octadecadienoic acids containing conjugated double bonds. These octadecadienoic acids have isomers with different configurations and conformations, such as : 9-c, 11-c; 10-c, 12-c; 9-t, 11-t; 10-t, 12-t; 9-t, 11-c; 9-c, 11-t; 10 -c, 12-t; 10-t, 12-c; 8, 10 and 11, 13 isomers were later found in French cheese. [0003] So far, studies have found that 9-c, 11-t and 10-t, 12-c are the two most abundant isomers in conjugated linoleic acid, and their chemical formula is: [0004] [0005] Conjugated linoleic acid has attracted the attention of more and more domestic and foreign scientific research and medical institutions for its excellent health care and disease resistance functions, and they ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/06A61K31/201A61K45/00A61P17/02A61P17/06A61P35/00
Inventor 董昕吾满江・艾力文彬张亚刚樊莉马莉
Owner XINJIANG TECHN INST OF PHYSICS & CHEM CHINESE ACAD OF SCI