Medicinal composition for get rid of opium drug dependence

A technology of opioid drugs and compositions, applied in the field of pharmaceutical compositions, which can solve problems such as greater danger to life, difficulty in controlling the dosage of drugs, and inability to get rid of the use of opioid receptor agonists

Inactive Publication Date: 2007-03-21
HANDAN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Drug detoxification treatment is a key part of drug detoxification. At present, opioid receptor agonist reduction and replacement, non-opioid receptor agonist symptomatic treatment, or deprivation of consciousness with narcotic drugs are commonly used in the world. There are also certain problems: the substitution therapy itself is easy to form new drug dependence; the dosage of anesthetics to deprive consciousness is difficult to control, and improper use is more harmful to life; non-opioid receptor agonists are difficult to treat multi-system comprehensive dise...

Method used

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  • Medicinal composition for get rid of opium drug dependence
  • Medicinal composition for get rid of opium drug dependence
  • Medicinal composition for get rid of opium drug dependence

Examples

Experimental program
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experiment example

[0025] Experimental example, the clinical trial summary report of the pill of the present invention for the treatment of opioid drug dependence detoxification

[0026] 1. Research method:

[0027] 1. Purpose: To preliminarily evaluate the detoxification therapeutic effect and adverse reactions of the pills of the present invention on opioid-dependent patients.

[0028] 2. Experimental design: open experiment.

[0029] 3. Test drug: pill of the present invention.

[0030] 4. Medication regimen:

[0031] Dosage: One pill each time.

[0032] Medication method: Dissolve the pill in warm water and take it orally.

[0033] 5. The number of test cases is 10 cases.

[0034] 6. Cure standard: the sum of the three symptoms of craving, anxiety, and insomnia within 72 hours is less than 10 points; all levels of withdrawal symptoms are recorded as 0; there is no obvious withdrawal symptoms after stopping the treatment.

[0035] 7. Observation and scoring: before the test, study the c...

Embodiment 1

[0121] Embodiment 1: oral liquid of the present invention

[0122] Take Codonopsis 350g, Paojiang 200g, Eucommia 100g, Poppy shell 400g, Poria cocos 100g, Tangerine peel 110g, Amomum 40g, Hawthorn 200g.

[0123] The above eight flavors, ginger, tangerine peel, and amomum are steam distilled to extract the volatile oil, collect the volatile oil, set aside, and store the liquid medicine separately; add the remaining five flavors of medicinal materials to the dregs, add water to decoct three times, add 10 times the amount of water for the first time, and decoct for 2 hours , add 8 times the amount of water for the second and third times, decoct for 1 hour, combine the liquid medicines, let stand, concentrate into an extract of 1.10-1.20, add volatile oil, preservatives, and flavoring agents, mix well, and adjust to 1000ml, ready to serve.

Embodiment 2

[0124] Embodiment 2: pill of the present invention

[0125] Take 400g Codonopsis, 150g Paojiang, 150g Eucommia, 350g Poppy Shell, 140g Poria, 80g Tangerine Peel, 80g Amomum, and 150g Hawthorn; grind the above eight flavors into fine powder, add appropriate amount of refined honey or honey water, and make a pill, that is, .

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Abstract

The invention discloses a medicinal composition for getting rid of opium drug dependence, wherein the medicinal composition comprises the following raw materials (by weight portion), codonopsis pilosula 300-500 weight parts, ginger 50-250 weight parts, eucommia bark 50-250 weight parts, poppy capsule 200-500 weight parts, poria cocos wolf 30-250 weight parts, dried orange peel 10-150 weight parts, amomum fruit 10-150 weight parts, and haw 50-250 weight parts.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to a pharmaceutical composition for opioid drug dependence detoxification. Background technique [0002] Drug abuse has become a public hazard in the world. The annual global drug trade has exceeded 50 billion US dollars. After the mid-1980s in our country, the residue of drug abuse emerged and developed rapidly. At present, the number of drug addicts officially announced by the Chinese government has reached 800,000, and the actual number is several times that, and the prevalence trend is still on the rise. There are now 31 provinces, municipalities directly under the central government, and 190 cities and counties officially reporting drug abuse. The annual direct consumption of drug funds is nearly 200 billion yuan. What is more serious is that it leads to loss of labor force, family destruction, increased crime, and the spread of AIDS. It can be seen that the harm of drugs to t...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61K36/9064A61K36/752A61K36/734A61K36/66A61K36/46A61K36/344A61K36/076A61P25/36
Inventor 陈致慜张成会李春雷
Owner HANDAN PHARMA
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