B-mode ultrasound coupling agent and its prepn

A coupling agent and B-ultrasound technology, applied in echo/ultrasonic imaging agents, etc., can solve problems such as cross-infection, damage to patients' health, inability to kill bacteria and viruses, and achieve simple production methods, health protection, and acoustic performance. excellent effect

Inactive Publication Date: 2002-10-16
黎国梓
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AI Technical Summary

Problems solved by technology

[0002] In ultrasonic diagnosis, in order to maximize the transmission of ultrasonic energy into the investigated organs, it is necessary to coat the sound-conducting medium with excellent acoustic performance between the ultrasonic probe and the skin --- B-ultrasound couplant, to fill the tiny space between the probe and the skin surface. In order to obtain clear and high-resolution ultrasonic images; ultrasonic inspection not only requires a dedicated ultrasonic probe, but also requires a small sound attenuation coefficient, sound velocity and acoustic impedance similar to human tissue, excellent acoustic performance, non-toxic and non-irritating to the human body , no sensitization, B-ultrasound coupling agent with good biocompatibility, and at present, the commonly used B-ultrasound coupling agent is a colloid solution composed of glycerin, sodium carboxymethylcellulose, ethanol, and purified water. Coupling effect cannot kill bacteria and viruses, causing cross-infection of B-ultrasound probes during use and damaging the health of patients

Method used

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Examples

Experimental program
Comparison scheme
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Embodiment Construction

[0007] safety experiment

[0008] 1. Local irritation test: Apply this product and normal saline to 5*10 square centimeters on both sides of the back of depilatory rabbits, observe for 48 hours, there is no redness, swelling, blisters or purple spots, and there is no difference from the part where normal saline is applied.

[0009] 2. Comparison of coupling effects: 30 cases of B-ultrasound liver and gallbladder examinations were performed with the coupling agent made by the present invention, and the inspection results were consistent with the effects of common coupling agents.

[0010] 3. Comparison of sterilizing effect: When performing B-ultrasound examination on the patient, wipe the probe clean with sterile toilet paper, wipe the probe twice with sterile cotton ball dipped in sterile saline, put the lotion in a sterile petri dish, add sterile Bacteria culture medium, shake well, after coagulation, carry out conventional culture, sample 20 cases, the result is as follows:...

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Abstract

The coupling agent for B-mode ultrasound diagnostic instrument consists of povidone-iodine 0.5-5 %, glycerin 1-7 %, sodium carboxy methyl cellulose 3-6 %, ethanol 10-15 % and pure water 67-85.5 %. During its preparation, povidone-iodine is first dissolved in water, sodium carboxyl methyl cellulose and ethanol are mixed homogeneously through stirring, the povidone-iodine solution is then mixed with mixed sodium carboxy methyl cellulose and ethanol solution through stirring, and the mixed solution is 80-120 mesh filtered to obtain the coupling agent. The coupling agent is used in supersonic test in hospital and can kill bacteria and virus and prevent crossed infection.

Description

technical field [0001] The invention relates to the technical field of B-ultrasonic coupling agent and preparation method thereof; Background technique [0002] In ultrasonic diagnosis, in order to maximize the transmission of ultrasonic energy into the investigated organs, it is necessary to coat the sound-conducting medium with excellent acoustic performance between the ultrasonic probe and the skin --- B-ultrasound couplant, to fill the tiny space between the probe and the skin surface. In order to obtain clear and high-resolution ultrasonic images; ultrasonic inspection not only requires a dedicated ultrasonic probe, but also requires a small sound attenuation coefficient, sound velocity and acoustic impedance similar to human tissue, excellent acoustic performance, non-toxic and non-irritating to the human body , no sensitization, B-ultrasound coupling agent with good biocompatibility, and at present, the commonly used B-ultrasound coupling agent is...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K49/22
Inventor 孟德宝黎国梓
Owner 黎国梓
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