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Liquid composition and its preparing method and use

A technology of liquid composition and weight percentage, applied in the direction of pharmaceutical formulations, etc., can solve the problems of poor compactness, long film-forming time, poor transparency, etc., and achieve the effects of good compactness, short film-forming time and comfortable feeling.

Inactive Publication Date: 2003-11-26
汪瑜
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the film formed by casein alone is hard, brittle, poor in transparency, and takes a long time to form a film. Its aqueous solution is applied on the skin, and its lubricity and spreadability are not good enough. For example, the patent application number 91109415 discloses a method for invisible A method for preparing a multifunctional skin care solution for gloves; although the compounding of cellulose and casein can overcome some shortcomings of casein film formation alone, such as hardness, brittleness, stickiness, etc., the formed film stays or smears on After being applied to the skin, the film-forming time is about 2-4 minutes longer, and the hygroscopicity is also very strong. In addition, casein is a natural polymer compound mainly composed of amino acids, which is mainly extracted from natural dairy products. Products formulated with polymer materials such as casein and cellulose must have a strong anti-corrosion system; if only cellulose is used to form a film, the compactness is relatively poor

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] Mix 3% PVP and 2.5% hydroxypropyl methylcellulose until uniform, then dissolve the mixture in water at 80-90°C; when the system is completely dissolved, add 0.3% trichlorohydroxy diphenyl ether , fully dissolve and mix until transparent, add the remaining water; then adjust the pH value to 6.0-7.0 with citric acid.

Embodiment 2

[0071] Mix 1% PVP and 0.5% hydroxypropyl methylcellulose until uniform, then dissolve the mixture in water at 80-90°C; when the system is completely dissolved, add 0.3% trichlorohydroxy diphenyl ether , fully dissolve and mix until transparent, add the remaining water; then adjust the pH value to 6.0-7.0 with citric acid.

Embodiment 3

[0073] Mix 1.5% PVP and 1% hydroxypropyl methylcellulose until uniform, then dissolve the mixture in water at 80-90°C; when the system is completely dissolved, add 0.3% trichlorohydroxy diphenyl ether , fully dissolve and mix until transparent, add the remaining water; then adjust the pH value to 6.0-7.0 with citric acid. The above product is a colorless transparent liquid with a certain viscosity. Apply on the hands, and it will form a film in about 1 minute, and it is lubricated and comfortable. According to needs, appropriate amount of pigment and essence can be added to present different colors and fragrances.

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PUM

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Abstract

The liquid composition is used to paint onto skin to form water soluble transparent film to sterilize and protect skin. The liquid composition consists of polyvinyl pyrrolidone 1-3 wt%, hydroxypropyl methyl cellulose 0.5-5 wt% or sodium alginate 1-3 wt%, trichlorohydroxy diphenyl ether or chlorhexidinium acetate 0.1-0.5 wt%, surfactants sodium dodecyl sulfate, nonyl phenol polyethenoxy ether and / or C20 alkyl glucoside 4.0-15.0 wt%, glycerine 3-10 wt%, EDTA-2Na 0.1-0.2 wt% and urea 0.1-1.0 wt%; and has pH value of 6.0-7.0. The liquid composition can form water soluble transparent compact and comfortable film in short time.

Description

technical field [0001] The invention relates to a liquid composition and its preparation method and application, especially the liquid composition capable of forming a water-soluble transparent film with sterilization function when applied to the skin of hands, its preparation method and application. Background technique [0002] As a skin protective film, invisible gloves can protect human skin, especially hands, from oil, weak acid, weak alkaline solution and some substances that damage human skin. Its main film-forming material is casein or cellulose, or a compound of casein and cellulose. However, the film formed by casein alone is hard, brittle, poor in transparency, and takes a long time to form a film. Its aqueous solution is applied on the skin, and its lubricity and spreadability are not good enough. For example, the patent application number 91109415 discloses a method for invisible A method for preparing a multifunctional skin care solution for gloves; although t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
Inventor 汪瑜
Owner 汪瑜
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