Ginseng stem leaf total saponin drip pill and its preparation method

A technology of ginseng stem, leaf and glycoside dropping pills is applied in the directions of pill delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc. Convenience and other issues, to achieve the effects of convenient carrying and taking, improved dissolution rate and dissolution rate, and simple production conditions

Inactive Publication Date: 2004-05-05
HONGYI SCI & TECH CO LTD NANCHANG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The total saponins of ginseng stems and leaves are bitter and hygroscopic, which affects the stability of capsules or sugar-coated tablets, and disintegrates slowly, with low dissolution rate and dissolution rate. It is inconvenient to take for children, the elderly, bedridden patients or patients with dysphagia. poor compliance

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0049] prescription:

[0050] Ginseng stem and leaf total saponins 5g

[0051] Macrogol 6000 15g

[0052] Makes 1000 capsules

[0053] Preparation method: Take the fine powder of ginseng stem and leaf total saponins that has been ultrafinely pulverized and passed through a 200-mesh sieve, add it to the molten polyethylene glycol 6000 matrix, stir well, use simethicone as a coolant, make pellets by dropping, dry, Instantly.

example 2

[0055] prescription:

[0056] Ginseng stem and leaf total saponins 5g

[0057] Macrogol 4000 15g

[0058] Makes 1000 capsules

[0059] Preparation method: Take the fine powder of ginseng stem and leaf total saponins that has been ultrafinely pulverized and passed through a 200-mesh sieve, add it to the molten polyethylene glycol 4000 matrix, stir well, use simethicone as a coolant, make pellets by dropping, dry, Instantly.

example 3

[0061] prescription:

[0062] Ginseng stem and leaf total saponins 5g

[0063] Macrogol 6000 5g

[0064] Macrogol 4000 10g

[0065] Makes 1000 capsules

[0066] Preparation method: Take the fine powder of ginseng stem and leaf total saponins that has been ultrafinely pulverized and passed through a 200-mesh sieve, add it to the molten polyethylene glycol 4000 and polyethylene glycol 6000 mixed matrix, stir well, use simethicone oil as a coolant, Drop system into legal pills, dry, and get it.

[0067] 4. Example 4

[0068] prescription:

[0069] Ginseng stem and leaf total saponins 5g

[0070] Glyceryl monostearate 15g

[0071] Makes 1000 capsules

[0072] Preparation method: Take the fine powder of ginseng stem and leaf total saponins that has been ultrafinely pulverized and passed through a 200-mesh sieve, add it to the molten glyceryl monostearate matrix, mix well, use ice water as a coolant, make pellets by dropping, dry, and have to.

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PUM

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Abstract

A dripping pill of ginseng stem and leaf's common saponin and its superfine pulverizing process for preparing it are disclosed. Its advantages are high dissolving and disintegrating speed, high stripping percentage, quickly taking its effect, high stability and low cost.

Description

technical field [0001] The invention relates to a medicine preparation and a preparation method thereof, in particular to ginseng stem and leaf total saponins dripping pills and a preparation method thereof. Background technique [0002] The total saponins of ginseng stems and leaves are the extracts of ginseng stems and leaves, which can enhance the body's stress ability, adjust endocrine and autonomic dysfunction, resist fatigue, enhance myocardial contractility, and improve cardiac output. Heart disease, climacteric syndrome, hidden diabetes and adjuvant medicine for tumors. Currently on the market, there are capsules and sugar-coated tablets of total saponins from stems and leaves of ginseng. [0003] The total saponins of ginseng stems and leaves are bitter and hygroscopic, which affects the stability of capsules or sugar-coated tablets, and disintegrates slowly, with low dissolution rate and dissolution rate. It is inconvenient to take for children, the elderly, bedri...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61K31/704A61P3/10A61P9/10A61P15/12A61P35/00
Inventor 钱进许军彭红李平刘孝乐
Owner HONGYI SCI & TECH CO LTD NANCHANG
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