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Medicine for treating angina pectoris and its preparation and application

An angina pectoris and drug technology, which is applied to the drug for the treatment of angina pectoris, the application field of the preparation of drugs for the treatment of angina pectoris, dyslipidemia and anti-atherosclerosis, can solve the problems of difficulty in treating both the symptoms and root causes, unsatisfactory curative effect, etc., and achieves prevention and treatment of lipids. Abnormal, platelet aggregation inhibition, antithrombotic improvement effect

Inactive Publication Date: 2004-11-03
无锡山禾药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It can be seen that the treatment of coronary arteriosclerosis, coronary heart disease and angina pectoris with lipid-lowering drugs or heart-protecting drugs alone has biased disadvantages, and it is difficult to treat both symptoms and root causes.
[0007] However, currently on the market, there are very few drugs for the treatment of coronary heart disease and angina pectoris that also have the effects of regulating lipids and protecting the heart.
Therefore, although there are many cardiovascular drugs, the curative effect is not satisfactory

Method used

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  • Medicine for treating angina pectoris and its preparation and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0061] Example 1: Preparation of capsules of the drug of the present invention

[0062] a) Weigh 3g of Puhuang, 2g of Pinellia ternata, 5g of Salvia miltiorrhiza and 2g of dried tangerine peel, and set aside;

[0063] b) The above weight ratio of Danshen and Pollen Typhae plus 55%-65% ethanol are refluxed and extracted twice, the alcohol extracts are combined, and the ethanol is recovered under reduced pressure to obtain a concentrated solution for use;

[0064] c) The dregs of b) and 2g of Pinellia ternata 2g and 2g of tangerine peel are decocted in water three times, each time adding water to immerse the medicinal noodles, filter, combine the filtrate, concentrate to a relative density of 1.15, and alcohol Extract the concentrated solution and mix well to obtain a clear ointment;

[0065] e) Add auxiliary materials, make granules, sizing, and dry, and pack them into capsules to obtain.

Embodiment 2

[0066] Example 2: Preparation of granules of the drug of the present invention

[0067] a) Weigh 12g each of the raw materials of Typhae Typhae, Pinellia ternata, and dried tangerine peel, and 18g of Salvia Miltiorrhiza for use;

[0068] b) 18g of Salvia miltiorrhiza and 12g of Pollen Typhae plus 70%-90% ethanol are refluxed and extracted twice, the alcohol extracts are combined, and the ethanol is recovered under reduced pressure to obtain a concentrated solution for use;

[0069] c) Distill the volatile oil by adding 150g of water to the dried tangerine peel of the above weight, collect the volatile oil for later use, add 7 times the amount of water to decocting the medicinal residue once, and combine the decoction and the distilled medicinal solution into solution 1 for later use;

[0070] d) Decoct the medicinal residue from step b) and 12g of Pinellia ternata with water for three times. Add water each time so that the medicinal noodles should be drenched. Combine the decoctio...

Embodiment 3

[0072] Example 3: Preparation of tablets of the drug of the present invention

[0073] a) Weigh 6g of Puhuang, 5g of Pinellia ternata, 9g of Salvia miltiorrhiza, and 5.5g of dried tangerine peel, and set aside;

[0074] b) Add 6g Puhuang and 9g Dan to 70%-90% ethanol reflux extraction for 2 times, combine the alcohol extracts, and recover the ethanol under reduced pressure to obtain a concentrated solution for use;

[0075] c) The dregs of step b), 5g of Pinellia ternata and 5.5g of dried tangerine peel are decocted in water three times. Each time the water is added to the medicinal noodles, the decocted liquid is concentrated to a relative density of 1.2, and extracted with alcohol. Mix the concentrated solution to obtain a clear ointment;

[0076] d) Add excipients, make granules, dry them, and compress them into tablets.

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Abstract

The present invention is medicine for treating angina pectoris and other diseases is prepared with pinellia tuber, red sage, dried orange peel and other Chinese medicinal materials in certain proportion. The medicine has functions of activating vital energy, promoting blood circulation, dispersing blood clots and stopping pain, and may be used in treating angina pectoris, atherosclerosis and hyperlipemia. It may be prepared into various orally taken preparation forms.

Description

Technical field [0001] The invention belongs to the field of traditional Chinese medicine. In particular, it is a medicine for treating angina pectoris, specifically a Chinese patent medicine prepared from Chinese herbal medicines. The present invention also relates to a preparation method of the medicine and its use in the preparation of medicines for the treatment of angina pectoris, dyslipidemia, and anti-atherosclerosis. Applications. Background technique [0002] Hyperlipidemia, atherosclerosis, coronary heart disease and angina pectoris are common and frequently-occurring clinical diseases. Epidemiological data confirm that the incidence and mortality of coronary heart disease (CHD) in my country are increasing year by year, the age of onset is earlier, and the incidence rate increases with the increase of blood total cholesterol (TC) level and blood pressure. Studies have confirmed that: Atherosclerosis (ASD) is a disabling and fatal systemic dise...

Claims

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Application Information

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IPC IPC(8): A61P9/10
Inventor 王震华徐瑞珍余灵芝施仕红张文威
Owner 无锡山禾药业股份有限公司
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