Lung cavity aeration liquid and its preparation method

A lung ventilator and perfluorodecalin technology, applied in the field of electrolysis of organic compounds, can solve the problems of not being able to directly improve the pulmonary physiological state of acute respiratory distress syndrome, increasing the danger of medical staff, and being difficult to reduce mortality, etc. Achieve the effects of improving the oxygenation state of the body, improving lung compliance and reducing mortality

Inactive Publication Date: 2005-01-19
SHANGHAI HUAJIE EYE MEDICAL EQUIP
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Problems solved by technology

[0002] According to the current domestic clinical methods for the treatment and rescue of acute respiratory distress syndrome, mechanical ventilation methods such as non-expiratory positive pressure ventilation, split-lung ventilation, and inverse ratio ventilation are basically used. In the fight against "SARS", it is necessary to cut the trachea for oxygen supplementation for patients with serious conditions, which will not only easily cause lung tissue damage, make it difficult to reduce the mortality rate, but also increase the risk of infection for medical staff

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  • Lung cavity aeration liquid and its preparation method

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preparation example Construction

[0012] The preparation method of lung cavity ventilation liquid is characterized in that: the preparation method comprises the following steps, a. adding potassium hydrogen fluoride into the first-stage reactor, and heating at 60-120°C for reaction, and the new ecological fluorine produced is directly put into React with metal cobalt in the second-stage catalytic reactor to directly produce cobalt trifluoride and heat the reactor to 150-350°C; b. Take naphthalene and dissolve it in an evaporator containing + hydrogenated naphthalene, and the mixture of naphthalene and + hydrogenated naphthalene The weight ratio is 1:1-1:10. Heat the evaporator to evaporate the solution and add it to the reactor in a gaseous state. The reaction product is collected in the crude product container; c. After the feeding is completed, the collected product in the crude product container is washed with distilled water , and dried over anhydrous sodium sulfate to obtain the crude product perfluorodeca...

Embodiment 1

[0028] The preparation method of the lung cavity ventilation liquid includes the following steps: a. Add potassium hydrogen fluoride to the first-stage reactor, heat at 70°C for reaction, and the new ecological fluorine produced is directly put into the second-stage catalytic reactor to react with metal cobalt directly Prepare cobalt trifluoride and heat to make the reactor temperature reach 300°C; b, get naphthalene and dissolve it in an evaporator filled with +hydronaphthalene, the weight ratio of naphthalene to +hydronaphthalene is 1:2, and the evaporator is heated to make the solution After evaporation, add in the reactor in gaseous form, and the reaction product is collected in the crude product container; c, after the feeding is completed, the collection in the crude product container is washed with distilled water, dried over anhydrous sodium sulfate, and the crude product perfluorodecalin is obtained. Heat and reflux in 20% KOH ethanol solution until the pH value of the...

Embodiment 2

[0030] The preparation method of the lung cavity ventilation liquid includes the following steps: a. Add potassium hydrogen fluoride to the first-stage reactor, and heat it at 110°C to react, and the new ecological fluorine produced is directly put into the second-stage catalytic reactor to react directly with metal cobalt Prepare cobalt trifluoride and heat to make the reactor temperature reach 180°C; b, get naphthalene and dissolve it in an evaporator filled with +hydronaphthalene, the weight ratio of naphthalene to +hydronaphthalene is 1:9, and the evaporator is heated to make the solution After evaporation, add in the reactor in gaseous form, and the reaction product is collected in the crude product container; c, after the feeding is completed, the collection in the crude product container is washed with distilled water, dried over anhydrous sodium sulfate, and the crude product perfluorodecalin is obtained. Heating and reflux in 20% KOH ethanol solution until the pH value...

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Abstract

The invention relates to a lung cavity venting liquid whose main composition is fluorine decahydronaphthalene, its boiling point is 140-142 deg. C, its specific density is above 1.9. The invention realizes a major tool for liquid venting, which can increase lung compliance substantially.

Description

Technical field: [0001] The invention relates to the technical field of electrolysis of organic compounds, in particular to a lung cavity ventilation liquid and a preparation method thereof. Background technique: [0002] According to the current domestic clinical methods for the treatment and rescue of acute respiratory distress syndrome, mechanical ventilation methods such as non-expiratory positive pressure ventilation, split-lung ventilation, and inverse ratio ventilation are basically used. In the fight against "SARS", it is necessary to cut the trachea for oxygen supplementation for patients with serious conditions, which not only easily causes lung tissue damage, makes it difficult to reduce mortality, but also increases the risk of infection for medical staff. Invention content: [0003] The object of the present invention is to provide a lung cavity ventilation liquid and a preparation method thereof, the lung cavity ventilation liquid can improve lung compliance,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/72A61K31/03C25B3/28
Inventor 张香平鲁俞方治文
Owner SHANGHAI HUAJIE EYE MEDICAL EQUIP
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