The invention discloses a method for adjusting tidal volume under an IPPV mode. The method comprises the following steps: 1) setting tidal volume, inspiration and expiration ratio, and respiratory frequency, according to the following formula, calculating inspiratory flow of an inhalation valve, inspiratory flow = set tidal volume / inspiratory time, inspiratory time=60 / respiratory frequency x (inspiratory time / (inspiratory time + expiratory time)); 2) through the inspiratory flow, according to a corresponding table of inhalation valve voltage and flow velocity, obtaining threshold voltage of the inhalation valve, after an expiration period, according to the following formula, calculating overall tidal volume, overall tidal volume = system compliance / (system compliance - pipeline compliance) x set tidal volume; 3) according to the following formula, calculating actual tidal volume, actual tidal volume = overall tidal volume - tidal volume consumed by a pipeline; 4) according to the difference value of the set tidal volume and the actual tidal volume, through adjusting inspiratory flow, adjusting the threshold voltage of the inhalation valve, so as to adjust the overall tidal volume. The method is simple and feasible.