47 results about "Lung ventilation" patented technology

The invention relates to the technical field of respiratory function monitoring, and discloses a pulmonary ventilation blood flow distribution real-time monitoring method and evaluation system based on a sensor. The method comprises the following steps: acquiring multi-modal data such as a blood oxygen saturation waveform, an airflow rate waveform and a thoracic pressure waveform of a lung area; performing time synchronization processing on the data to generate a time alignment sequence; dividing the data into an inspiration phase, an expiration phase and a transition phase according to a preset rule; extracting time-frequency domain features from each phase segment, and constructing a multi-dimensional respiration feature matrix; identifying an abnormal breathing mode and marking an abnormal section through breathing phase switching frequency analysis; decomposing the normal segment feature matrix by using a lung pathological feature library to generate a pathological feature vector; a pathological feature vector is optimized through a ventilation and blood flow coupling model; and carrying out abnormal region positioning based on the lung pathology propagation network, and generating a lung partition function evaluation result. The method realizes non-invasive and real-time monitoring, and is suitable for scenes such as clinical monitoring and rehabilitation evaluation.

The invention relates to the technical field of medical care, in particular to an intelligent early warning system for dynamic deterioration of chronic obstructive pulmonary disease, which is used for solving the technical problem of inaccurate evaluation of lung ventilation capability of a user in the prior art. The system comprises a data acquisition unit used for acquiring lung function time sequence data and multi-dimensional physiological time sequence data of a target user in an observation stage; the observation phase comprises a plurality of consecutive dates; the processing unit is used for determining suspected abnormal days according to the lung function time sequence data, determining the deviation degree of the multi-dimensional physiological time sequence data of the suspected abnormal days and the multi-dimensional physiological time sequence data of the reference day and the similarity of the deviation degree of the physiological time sequence data of different dimensions, determining the abnormal days from the suspected abnormal days based on the deviation degree and the similarity, and sending the abnormal days to the user. The chronic obstructive pulmonary disease dynamic deterioration risk level of the target user is determined based on the abnormal days; and performing risk early warning based on the chronic obstructive pulmonary disease dynamic deterioration risk level of the target user.

The present application relates to the technical field of health care, in particular to an intelligent early warning system for dynamic exacerbation of chronic obstructive pulmonary disease, which is used to solve the technical problem of inaccurate assessment of lung ventilation capacity of users in the prior art. The system comprises: a data acquisition unit for acquiring lung function time series data and multi-dimensional physiological time series data of a target user in an observation period; the observation period comprises a plurality of consecutive days; a processing unit for determining suspected abnormal days according to the lung function time series data, determining the deviation degree of the multi-dimensional physiological time series data of the suspected abnormal days and the multi-dimensional physiological time series data of the reference days and the similarity of the different dimensional physiological time series data deviation degrees, determining the abnormal days from the suspected abnormal days based on the deviation degree and the similarity, and determining the dynamic exacerbation risk level of the target user's chronic obstructive pulmonary disease based on the abnormal days; and performing risk warning based on the dynamic exacerbation risk level of the target user's chronic obstructive pulmonary disease.

The invention discloses a method for preparing a VA-ECMO lung injury treatment medicine by using ginkgolide A to regulate YARS1, and relates to the technical field of biological medicine, the method comprises the following steps: by using ginkgolide A as a YARS1 protein regulator, preparing the medicine for treating the VA-ECMO lung injury through virtual screening, binding affinity confirmation and cell efficacy confirmation; wherein the virtual screening is based on a protein structure model of YARS1, and bilobalide A with high affinity binding energy with YARS1 is screened out through molecular docking. It is proved that ginkgolide A can effectively improve the lung ventilation function by regulating YARS1, repair the alveolar epithelial barrier structure and inhibit the inflammatory oxidative stress reaction, and the lung injury treatment effect and clinical transformation safety under the support of VA-ECMO are improved.

The present disclosure provides a unique solution for assisting in the ventilation of lungs of subject that is performed by artificial mechanical ventilator. The solution of the present invention improves the efficiency of the ventilation effect by applying desired pressure profile on portions of the upper body part of the subject in synchronization with the mechanical ventilator operation, thereby creating a desired pressure profile or gradient in the lungs airways to ensure that air pumped into the lungs by the mechanical ventilator spreads more homogeneously in the lungs than without the intervention of the system of the present invention. The application of pressure is determined after analyzing data from sensors of the system that are placed on a plurality of portions on the upper body part of the subject and data received from the mechanical ventilator. These sensors sense data indicative of the ventilation profile within the lungs, i.e. pressure profile along different portions of the lung. The system provides extra-thoracic pressure on the rib cage according to pre-defined and adaptive algorithms based on the physiological status, the respiratory mechanics, and the inhomogeneous nature of lung injury. By applying pressure to the hyperventilated areas and reducing the transpulmonary pressure gradient, the system prevents hyperinflation trauma to the open areas and atelecto-trauma to the closed areas. The system is synchronized with the mechanical ventilator and adapt to changes in the patient's respiratory mechanics.

The invention discloses a thoracic operation single-lung ventilation monitoring device and monitoring method based on an EIT technology, the thoracic operation single-lung ventilation monitoring device comprises a plurality of monitoring modules, each monitoring module comprises an electrode membrane and an electrode array, the electrode array is integrated on the electrode membrane, and the electrode membrane is provided with a first adhesive layer so as to be adhered to the body surface of a human body; the system further comprises a receiving host detachably arranged on the single side of the human body surface, a receiving module and a wireless module are arranged in the receiving host, the receiving module is electrically connected with the multiple electrode arrays so as to receive impedance change data of each electrode array, the receiving module is electrically connected with the wireless module, and the wireless module is electrically connected with the receiving module. The wireless module is electrically connected with an external EIT device, and the external EIT device receives impedance change data of each electrode array and converts voltage data into a two-dimensional cross-sectional image. The one-lung ventilation monitoring of the EIT technology during the thoracic operation can be realized, the protective ventilation of the lung is realized, the oxygenation index is improved, the occurrence rate of hypoxemia is reduced, and the pulmonary complications are reduced.

A system and method for quantifying pulmonary ventilation and perfusion gradients in a subject's lungs, wherein local Hounsfield density histograms are generated from computed tomography data and each local histogram is cross-correlated with a global Hounsfield density histogram at a number of different shift values, and a final shift value is determined for each local histogram based on the correlation values ​​obtained by the cross-correlation.

The application relates to the technical field of medical image processing, and particularly discloses a lung ventilation function evaluation system based on CT images, which adopts deep learning-based image processing technology to analyze lung CT images at the end of inspiration and expiration of a patient, so as to extract semantic feature representations of the lung CT images, and then, through fine-grained semantic interaction and semantic compensation of the lung CT image features at the end of inspiration and expiration, accurate characterization of a lung deformation field is obtained, and the lung capacity of the patient is intelligently estimated. In this way, non-invasive and accurate evaluation of lung function can be realized, and the method is particularly suitable for a patient group with poor physical conditions or unable to complete standard breathing tests as required.

The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine composition for treating chronic obstructive pneumonia and a pharmaceutical preparation. The traditional Chinese medicine composition comprises blackberry lily, honey-fried ephedra, dried ginger, asarum, honey-fried aster, honey-fried tussilago farfara, exocarpium citri rubrum, schisandra chinensis, fried semen raphani, perillaseed, semen brassicae and liquorice. The traditional Chinese medicine composition and the pharmaceutical preparation provided by the invention are used for patients with chronic obstructive pneumonia, can recover the pulmonary ventilation function, effectively inhibit inflammatory response in the body and promote lung tissue injury repair, and have a relatively good treatment effect on chronic obstructive pneumonia.

An assistance apparatus for carrying out a first emergency care procedure, such as chest compressions or pulmonary ventilation, is configured to cooperate with a second assistance apparatus for carrying out a second emergency care procedure. The assistance apparatus comprises a communication device designed to receive, from the second assistance apparatus, data relating to the second emergency care procedure. The data comprises at least one item of information, a parameter or an instruction. A signal-processing device is configured to process the at least one signal measured according to the received data relating to the second emergency care procedure. An assistance system, comprising a compression assistance apparatus and a ventilation assistance apparatus, and an assistance method associated with the assistance system are also disclosed.

The application discloses a thoracico-abdominal motion respiration flow monitoring method and device, and relates to the field of respiration monitoring. The method comprises the following steps: acquiring a pressure value of a patient pressure monitoring point; the pressure monitoring point comprises a thoracic pressure monitoring point and an abdominal pressure monitoring point; performing data analysis according to the pressure value to determine a displacement change amount of the pressure monitoring point relative to an initial spatial coordinate; performing nonlinear fitting according to the displacement change amount to determine a thoracic volume change amount and an abdominal volume change amount; determining a respiration parameter according to the thoracic volume change amount and the abdominal volume change amount; the respiration parameter comprises a total lung ventilation, a thoracic respiration contribution ratio, an abdominal respiration contribution ratio and a thoraco-abdominal phase difference. The application realizes low-cost and high-precision respiration flow monitoring.

A system and method for quantifying a pulmonary ventilation and perfusion gradient of a lung of a subject. Local Hounsfield density histograms are generated from computed tomography imaging data and each local histogram is cross-correlated with a global Hounsfield density histogram at a plurality of different shift values. A final shift value is determined for each local histogram based on the correlation values obtained by the cross-correlation.

The application relates to a lung tissue isolator, belonging to the technical field of medical devices, which comprises a first chest wall outer ring body, a first chest wall inner ring body and a mediastinal ring body, a first isolation film is arranged between the first chest wall outer ring body and the first chest wall inner ring body, the first isolation film is surrounded to form a first isolation cavity, a second isolation film is arranged between the first chest wall inner ring body and the mediastinal ring body, the second isolation film is surrounded to form a second isolation cavity, a support is arranged in the second isolation film, the support is used for supporting the second isolation film, and the first isolation cavity and the second isolation cavity are communicated to form a viewing channel. The second isolation film is used together with the support to isolate lung tissue, prevent lung tissue from expanding over the isolator into an upper cardiac surgery area along with respiration, and provide a good surgery view for thoracoscopy or chest wall lateral intercostal incision cardiac surgery while maintaining double lung ventilation.

This invention belongs to the field of pulmonary rehabilitation training assessment technology, specifically involving a method for postoperative pulmonary rehabilitation training assessment and guidance guided by ultrasound in the lung and diaphragm system. By comparing postoperative parameters with baseline datasets, this invention can identify areas of diaphragmatic movement disorder and abnormal lung ventilation, overcoming the limitations of traditional assessment methods that rely solely on single indicators or subjective symptoms. Based on a sliding window mechanism, it calculates deviations in movement and ventilation parameters and matches them with standardized training parameters, initially establishing a correlation between the training program and the patient's degree of functional impairment. Furthermore, by collecting the patient's adaptation parameters under free training to generate sensitivity coefficients, the standardized training parameters are dynamically corrected until the patient reaches a stable adaptation state. This fully considers individual patient differences and real-time physiological feedback, transforming the training program from standardized to personalized, and achieving real-time quantitative monitoring and guidance of both the diaphragm and lung tissue.

The invention discloses a diaphragm stimulation control method and device, equipment, a storage medium and a program product. The method comprises the following steps: acquiring human chest impedance data through an electrical impedance tomography technology, and constructing a first lung ventilation image sequence according to the human chest impedance data; a global ventilation volume curve is extracted from the first lung ventilation image sequence, breathing cycle key points are determined according to the global ventilation volume curve, and the breathing cycle key points comprise at least one of an inspiration starting point, an inspiration peak point, an expiration starting point and an expiration end point; determining the inspiration triggering opportunity of the next cycle according to the breathing cycle key points, triggering diaphragm electrical stimulation according to the inspiration triggering opportunity, and collecting a stimulated second lung ventilation image sequence; and extracting a ventilation effect feedback index from the second lung ventilation image sequence, and adaptively adjusting diaphragm electrical stimulation parameters according to the ventilation effect feedback index.

The application discloses an implantable breathing assisting device, which comprises fixed magnetic sheets and moving magnetic sheets matched with each other, and an auxiliary air bag, when in an expiration phase, the fixed magnetic sheets and the moving magnetic sheets repel each other, the lung body contracts to exhale gas, and sterile gas in the auxiliary air bag is retracted to form an air bag between the lung body and a thoracic cavity; when in an inspiration phase, the fixed magnetic sheets and the moving magnetic sheets attract each other, the lung body expands to inhale gas, and the sterile gas in the auxiliary air bag gathers to form an air bubble at a lung tip of the lung body, the application can obviously improve lung ventilation and lung gas exchange functions, improve lung breathing, and can be used for treatment of most current lung diseases causing respiratory insufficiency, especially chronic obstructive pulmonary diseases and respiratory related infectious diseases, and even patients needing long-term use of a breathing machine to assist breathing, and is also suitable for patients with respiratory insufficiency caused by other diseases.

According to the three-dimensional lung ventilation imaging method and device, the lung ventilation condition of each lung area in the three-dimensional space can be presented, the operation efficiency is improved, the depth estimation of the three-dimensional lung is more accurate, the three-dimensional lung is not limited to orthogonality body position projection data of the normal position and the lateral position, and the three-dimensional lung ventilation imaging method and device are particularly suitable for bedridden patients. The method comprises the following steps: (1) inputting X-ray data of a normal position and an oblique position of a chest; (2) integrating the X-ray data of the normal position and the oblique position of the chest, matching the data of the normal position and the oblique position of the same breathing time phase, and mapping the two-dimensional data of the normal position and the oblique position into a three-dimensional space; (3) estimating a free deformation FFD parameter and a double-lung translation parameter by using the input data; (4) obtaining an optimal three-dimensional lung surface model estimation and a lung template number by using the parameters in the step (3); (5) voting according to the three-dimensional lung surface model estimation of each frame and the optimal lung template to obtain a global optimal lung template number; and (6) estimating three-dimensional lung ventilation parameters according to the sequential three-dimensional lung surface model.

The present application relates to the field of medical imaging technology, specifically to a COPD early warning method and system based on chest CT parameters, comprising the following steps: based on chest CT image data, extracting pixel data of lung lobe anatomical region, segmenting airway tree structure, identifying bronchial wall boundary, screening gradient change points, and generating airway wall boundary point set. In the present application, by refining the lung lobe anatomical region, segmenting the airway tree structure, accurately positioning the bronchial wall boundary, calculating the airway wall thickness, correcting abnormal fluctuations, improving the stability of the thickness parameter, using the thickness parameter to calculate the airflow passage cross-sectional area, analyzing the lung lobe ventilation volume and ventilation change, quantifying the lung ventilation imbalance degree, screening the ventilation restricted area, analyzing the relationship between the wall thickness and the ventilation change rate, extracting the abnormal growth area, marking the ventilation restriction severity, setting the early warning threshold, calculating the abnormal index mean value, marking the risk area, enhancing the ventilation abnormality recognition hierarchy, and improving the early warning ability of COPD.

The invention relates to a dynamic X-ray image matching method and system and a dynamic X-ray camera, and relates to the technical field of dynamic X-ray image matching. The dynamic X-ray image matching method comprises the following steps: determining whether a plurality of dynamic X-ray two-dimensional chest images in the breathing process comprise a set target or not; if yes, a set target X-ray two-dimensional chest image corresponding to the set target is extracted from the multiple dynamic X-ray two-dimensional chest images in the breathing process; matching is carried out on the basis of a lung airflow and blood flow mixed image sequence corresponding to the set target X-ray two-dimensional chest image or a lung airflow and blood flow mixed image and a lung blood flow image sequence corresponding to multiple X-ray two-dimensional chest images at multiple moments in a breath-holding state; and obtaining lung ventilation corresponding to the set target X-ray two-dimensional chest image. According to the embodiment of the invention, dynamic X-ray image matching can be realized, and then lung ventilation is determined.

This invention provides the use of a trisaccharide compound with a core structure of GlcN(1→4)IdoA(1→4)GlcNS in the preparation of a medicament for treating or preventing pulmonary fibrosis. This medicament can improve pulmonary inflammatory responses, reduce the degree of damage to lung tissue structure, improve or inhibit or delay the progression of pulmonary fibrosis, and ultimately improve and enhance pulmonary ventilation function in patients with pulmonary fibrosis.

The application provides a fermented composition for moistening and nourishing the lung and a preparation method. The fermented composition comprises the following components in parts by mass: 20-60 parts of yam, 15-40 parts of dark plum, 10-30 parts of polygonatum, 10-30 parts of ginkgo, 5-25 parts of raphanus, 0.3-3 parts of fermented bacteria powder and 3.1-13 parts of enzyme preparation. The fermented composition with the function of moistening and nourishing the lung is prepared by the joint action of the fermented bacteria powder and the enzyme preparation on the five main components of the food and medicine.

The invention provides a traditional Chinese medicine composition for treating pulmonary arterial hypertension and application thereof, and belongs to the technical field of traditional Chinese medicine preparation. The traditional Chinese medicine composition for treating pulmonary arterial hypertension is prepared from the following components in parts by weight: 5-7 parts of herba ephedrae, 7-9 parts of semen armeniacae amarae, 20-24 parts of gypsum, 5-7 parts of liquorice root, 9-11 parts of radix salviae miltiorrhizae, 0.8-1.2 parts of leech and 2.5-3.5 parts of radix notoginseng. According to the treatment principle of freeing lung, relieving asthma and promoting blood circulation to remove blood stasis, ephedra, apricot kernel, gypsum and licorice granules with the effects of freeing lung, clearing heat and relieving asthma are used as monarch drugs, and salvia miltiorrhiza, leech and pseudo-ginseng with the effects of promoting blood circulation to remove blood stasis are used as ministerial drugs for compatibility; the prepared traditional Chinese medicine composition can reduce the length ratio of the right ventricle to the left ventricle plus ventricular septum and the length ratio of the right ventricle to the tibia, inhibit right ventricular hypertrophy, repair pulmonary vascular injury and improve the pulmonary ventilation function, the cardio-pulmonary function and pulmonary arterial hypertension.

1. Name of the product in this design: Ventilator (Changhuxi-D1). 2. Purpose of this design: To provide or increase lung ventilation for patients dependent on ventilators. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The present invention relates to systems and methods for monitoring impedance from a sensor in the chest of a subject to determine the status of lung inflation or presence of pneumothorax in the subject, the presence of pulmonary edema, the status of regional lung ventilation, and the status of cardiac contractility.

This utility model provides a respiratory training device for geriatric patients, relating to the field of respiratory technology. It includes a three-way tube with annular screw grooves at each of its three ends. A fixed nozzle, a vertical cylinder, and a horizontal cylinder are respectively threaded onto and connected to the three ends of the three-way tube within the annular screw grooves. The bottom of the vertical cylinder has symmetrical fan holes, and the inner wall of each fan hole has a circular cavity. A first fan plate is embedded inside the circular cavity. A sphere is embedded inside the vertical cylinder. The inner wall of the horizontal cylinder has an L-shaped annular groove, and an L-shaped conical toothed ring is embedded and rotatably connected inside the L-shaped annular groove. A second fan plate is fixedly connected inside the L-shaped conical toothed ring. This utility model can flexibly achieve bidirectional training of inhalation and exhalation, adapting to the different respiratory rehabilitation needs of elderly patients, comprehensively exercising respiratory muscles, optimizing breathing patterns, improving lung ventilation and gas exchange functions, and assisting in the rehabilitation of lung diseases and the recovery of postoperative respiratory function.

The adjustable single-cavity tracheal catheter comprises a hollow catheter body, an air inlet and a first air outlet are formed in the top end and the bottom end of the catheter body respectively, a second air outlet is formed in the position, 2-3 cm away from the bottom end, of the side wall of the catheter body, and the catheter body is sleeved with a first outer air bag and a second outer air bag. The first outer air bag and the second outer air bag are arranged above and below the second air outlet respectively, an inner air bag is arranged in the catheter body and below the second air outlet, a moving groove is formed in the side wall of the second air outlet, a channel communicated with the top end of the side wall of the catheter body is formed in the top end of the moving groove, and the moving groove is slidably connected with a blocking piece. An annular air bag is arranged in the middle of the blocking piece, the first outer air bag, the second outer air bag, the inner air bag and the annular air bag are connected with different air inlet valves through air inlet pipes respectively, the air inlet pipes connected with the annular air bag are connected with the channel in a sliding mode, and therefore the problem of acute desaturation caused by the fact that an existing double-cavity tracheal catheter is small in inner diameter or too large in pipe diameter and cannot be inserted is solved.

The invention discloses a pulmonary ventilation function simulation analysis method combined with respiratory physiological parameters. The method comprises the following module components: a respiratory physiological parameter acquisition module, a pulmonary ventilation digital twinning module, a pathological state simulation analysis module, a clinical decision support module and a safety redundancy module. Comprising the following steps: step 1, preoperative preparation; 2, respiratory physiological parameters are collected; 3, performing digital twinning modeling on pulmonary ventilation; 4, pathological state simulation and analysis; 5, outputting and intervening clinical decisions; step 6, performing post-operation follow-up and model iteration; the invention aims to provide a pulmonary ventilation function simulation analysis method in combination with respiratory physiological parameters to solve the problems that only static parameters at a fixed time point can be collected, dynamic pathological scenes such as airway spasm and mucus blockage cannot be simulated, actual illness state changes of a patient are difficult to restore, doctors mostly depend on one-by-one comparison of parameters such as FVC and SpO2, and the accuracy is high. And deviation is easily caused by subjective judgment.

The invention discloses an EIT region segmentation and quantitative analysis method and system based on ultrasonic anatomy calibration, and belongs to the field of medical image and respiratory physiology monitoring. Processing the ultrasound image to identify anatomical markers such as a rib line, a pleural line and a diaphragm line; performing multi-modal image registration based on the physical coordinates and the common anatomical anchor points; mapping the anatomical landmark to an EIT grid; performing hierarchical constraint region segmentation on the EIT grid; and calculating an impedance average value and a tidal impedance variation based on a segmentation result. According to the method, individualized accurate region segmentation of the EIT image is achieved through ultrasonic anatomical structure calibration, data pollution is avoided, the EIT can provide a quantitative report with a clear anatomical identifier, and the application value and reliability of the EIT in clinical scenes such as pulmonary ventilation efficiency evaluation, pulmonary edema monitoring and pleural effusion quantification are greatly improved.

The invention relates to the technical field of traditional Chinese medicines, and provides an external traditional Chinese medicine composition for promoting intestinal function recovery after thoracic surgery, which comprises the following components in parts by weight: 3-40 parts of rheum officinale, 2-36 parts of mangnolia officinalis, 1-25 parts of immature bitter orange, 1-25 parts of mirabilite, 1-25 parts of semen raphani, 1-25 parts of fructus cannabis and 1-10 parts of fructus evodiae. The composition is designed according to a formula from the comprehensive conditioning angles of relaxing bowels, removing heat, promoting the circulation of qi, removing food stagnation, relaxing bowel and the like, and is reasonable in compatibility, so that the composition can promote postoperative exhaust and defecation, contributes to promoting intestinal function recovery, and avoids poor nutritional status of gastrointestinal tracts, diaphragm uplift caused by intestinal cavity flatulence, limitation of respiratory activity and aggravation of pulmonary ventilation disorder; the traditional Chinese medicine composition has the remarkable effects of promoting postoperative exhaust and defecation, improving abdominal distension and promoting digestion, is simple, is derived from improvement of a classic famous formula and is more suitable for postoperative weak patients.