The invention relates to a synthetic method of 1, 1, 3, 5-tetramethyl-3-
isopropyl hydrindene. The synthetic method specifically comprises the following steps: S1, uniformly mixing p-cymene, chlorotert-
butane and 2, 3-dimethyl-1-
butene, dropwise adding an obtained
mixed solution into a reaction kettle filled with
cyclohexane and
aluminum trichloride, stirring for reaction, washing with water and alkali for
elution, and rectifying to remove p-cymene, so as to obtain a 1, 1, 3, 4, 4, 6-hexamethyltetrahydronaphthalene crude product; S2, transferring the 1, 1, 3, 4, 4, 6-hexamethyl tetrahydronaphthalene crude product obtained in the step S1 into an
isomerization kettle, then adding
dichloroethane and
aluminum trichloride, and carrying out stirring, heating and
reflux reaction; S3, washing a product obtained after the
isomerization reaction with water and alkali until the product is neutral, desolventizing to remove
dichloroethane, transferring an obtained desolventized 1, 1, 3, 5-tetramethyl-3-
isopropyl hydrindene crude product into a
crystallization kettle, adding a
crystallization solvent, and recrystallizing for multiple times to obtain the 1, 1, 3, 5-tetramethyl-3-
isopropyl hydrindene. According to the synthetic method of the 1, 1, 3, 5-tetramethyl-3-isopropyl hydrindene, provided by the invention, the yield of a target product is improved, and the purification difficulty is reduced.